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Last Updated: September 29, 2023

Investigational Drug Information for Palovarotene


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What is the drug development status for Palovarotene?

Palovarotene is an investigational drug.

There have been 10 clinical trials for Palovarotene. The most recent clinical trial was a Phase 2 trial, which was initiated on November 28th 2017.

The most common disease conditions in clinical trials are Myositis Ossificans, Osteophyte, and Osteochondromatosis. The leading clinical trial sponsors are Clementia Pharmaceuticals Inc., Ipsen, and [disabled in preview].

There are fifteen US patents protecting this investigational drug and one hundred and eighty-five international patents.

Recent Clinical Trials for Palovarotene
TitleSponsorPhase
A Rollover Study to Further Evaluate the Safety and Efficacy of Palovarotene Capsules in Male and Female Participants Aged ≥14 Years With Fibrodysplasia Ossificans Progressiva (FOP) Who Have Completed the Relevant Parent Studies.IpsenPhase 3
Study Evaluating the Effect of Food on the Pharmacokinetics of Palovarotene and the Effect of Palovarotene on the Pharmacokinetics of the CYP3A4 Substrate Midazolam in Two Cohorts of Healthy Adult SubjectsClementia Pharmaceuticals Inc.Phase 1
Study to Assess Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of Palovarotene Ophthalmic Solution in Healthy Adult SubjectsIpsenPhase 1

See all Palovarotene clinical trials

Clinical Trial Summary for Palovarotene

Top disease conditions for Palovarotene
Top clinical trial sponsors for Palovarotene

See all Palovarotene clinical trials

US Patents for Palovarotene

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Palovarotene ⤷  Try a Trial Therapeutic agent for keratoconjunctive disorders YAMAGUCHI UNIVERSITY (Yamaguchi, JP) ⤷  Try a Trial
Palovarotene ⤷  Try a Trial Controlled release dosage form TRIASTEK, INC. (Nanjing, CN) ⤷  Try a Trial
Palovarotene ⤷  Try a Trial Inhibitors of activin receptor-like kinase BLUEPRINT MEDICINES CORPORATION (Cambridge, MA) ⤷  Try a Trial
Palovarotene ⤷  Try a Trial Composition and method for muscle repair and regeneration Thomas Jefferson University (Philadelphia, PA) ⤷  Try a Trial
Palovarotene ⤷  Try a Trial Small molecule agonists and antagonists of NR2F6 activity in animals Zander Therapeutics, Inc. (La Mesa, CA) ⤷  Try a Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Palovarotene

Drugname Country Document Number Estimated Expiration Related US Patent
Palovarotene Australia AU2013342882 2032-11-08 ⤷  Try a Trial
Palovarotene Australia AU2018217197 2032-11-08 ⤷  Try a Trial
Palovarotene Brazil BR112015010428 2032-11-08 ⤷  Try a Trial
Palovarotene Canada CA2890424 2032-11-08 ⤷  Try a Trial
Palovarotene Chile CL2015001225 2032-11-08 ⤷  Try a Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

Colorcon
McKesson
Boehringer Ingelheim
Merck
Harvard Business School
McKinsey

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