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Last Updated: September 22, 2021

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Investigational Drug Information for PTI-428


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What is the drug development status for PTI-428?

PTI-428 is an investigational drug.

There have been 26 clinical trials for PTI-428. The most recent clinical trial was a Phase 3 trial, which was initiated on March 1st 2016.

The most common disease conditions in clinical trials are Alzheimer Disease, Cystic Fibrosis, and Fibrosis. The leading clinical trial sponsors are Proteostasis Therapeutics, Inc., Pain Therapeutics, and Cassava Sciences, Inc.

There are two US patents protecting this investigational drug and twenty international patents.

Recent Clinical Trials for PTI-428
TitleSponsorPhase
Simufilam 50 mg or 100 mg for Mild-to-Moderate Alzheimer's DiseasePremier Research International LLCPhase 3
Simufilam 50 mg or 100 mg for Mild-to-Moderate Alzheimer's DiseaseCassava Sciences, Inc.Phase 3
A Phase 3 Study of Simufilam 100 mg in Subjects With Mild-to-Moderate Alzheimer's DiseasePremier Research International LLCPhase 3

See all PTI-428 clinical trials

Clinical Trial Summary for PTI-428

Top disease conditions for PTI-428
Top clinical trial sponsors for PTI-428

See all PTI-428 clinical trials

US Patents for PTI-428

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
PTI-428 ⤷  Free Forever Trial Compounds, compositions, and methods for increasing CFTR activity Proteostasis Therapeutics, Inc. (Boston, MA) ⤷  Free Forever Trial
PTI-428 ⤷  Free Forever Trial Compounds, compositions, and methods of increasing CFTR activity Proteostasis Therapeutics, Inc. (Boston, MA) ⤷  Free Forever Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

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Serving leading biopharmaceutical companies globally:

Medtronic
McKinsey
Mallinckrodt
Merck
Express Scripts
Boehringer Ingelheim

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