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Last Updated: October 18, 2019

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Drugs in Development Information for PLX3397

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Development status for investigational drug PLX3397: Sponsors, patents, clinical trial progress

PLX3397 is an investigational drug.

There have been 21 clinical trials for PLX3397. The most recent clinical trial was a Phase 2 trial, which was initiated on March 1st 2015.

The most common disease conditions in clinical trials are Melanoma, Breast Neoplasms, and Leukemia. The leading clinical trial sponsors are Plexxikon, National Cancer Institute (NCI), and QuantumLeap Healthcare Collaborative.

There are fourteen US patents protecting this investigational drug and one hundred and thirty-two international patents.

Recent Clinical Trials for PLX3397
TitleSponsorPhase
Biomarker Study of PDR001 in Combination With MCS110 in Gastric CancerSeoul National University HospitalPhase 2
A Study of PLX3397 in Patients With Unresectable or Metastatic KIT-mutated MelanomaPlexxikonPhase 1/Phase 2
Evaluation of Safety and Activity of an Anti-PDL1 Antibody (DURVALUMAB) Combined With CSF-1R TKI (PEXIDARTINIB) in Patients With Metastatic/Advanced Pancreatic or Colorectal CancersAstraZenecaPhase 1

See all PLX3397 clinical trials

Clinical Trial Summary for PLX3397

Top disease conditions for PLX3397
Top clinical trial sponsors for PLX3397

See all PLX3397 clinical trials

US Patents for PLX3397

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
PLX3397   Start Trial Synthesis of a compound that modulates kinases Plexxikon Inc. (Berkeley, CA) Daiichi Sankyo Company, Limited (Tokyo, JP)   Start Trial
PLX3397   Start Trial Solid forms of a compound modulating kinases Plexxikon Inc. (Berkeley, CA)   Start Trial
PLX3397   Start Trial Compounds modulating c-fms and/or c-kit activity and uses therefor Plexxikon, Inc. (Berkeley, CA)   Start Trial
PLX3397   Start Trial Compounds modulating c-fms and/or c-kit activity and uses therefor Plexxikon Inc. (Berkeley, CA)   Start Trial
PLX3397   Start Trial Compounds modulating c-fms and/or c-kit activity Plexxikon Inc. (Berkeley, CA)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for PLX3397

Drugname Country Document Number Estimated Expiration Related US Patent
PLX3397 Australia 2016258027 2035-05-06   Start Trial
PLX3397 Brazil 112017023490 2035-05-06   Start Trial
PLX3397 Brazil 112017023540 2035-05-06   Start Trial
PLX3397 Canada 2984899 2035-05-06   Start Trial
PLX3397 Canada 2984910 2035-05-06   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Medtronic
Baxter
Mallinckrodt
AstraZeneca
Express Scripts

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