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Last Updated: January 26, 2020

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Drugs in Development Information for PF-06463922

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What is the drug development status for PF-06463922?

PF-06463922 is an investigational drug.

There have been 12 clinical trials for PF-06463922. The most recent clinical trial was a Phase 1 trial, which was initiated on April 7th 2017.

The most common disease conditions in clinical trials are Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, and Lymphoma, Large-Cell, Anaplastic. The leading clinical trial sponsors are Pfizer, National Cancer Institute (NCI), and University of Milano Bicocca.

There are eleven US patents protecting this investigational drug and one hundred and sixty international patents.

Recent Clinical Trials for PF-06463922
TitleSponsorPhase
A Study of Lorlatinib in ALK Inhibitor‑Treated ALK‑Positive NSCLC in ChinaPfizerPhase 2
Biomarker/ALK Inhibitor Combinations in Treating Patients With Stage IV ALK Positive Non-Small Cell Lung Cancer (The NCI-NRG ALK Master Protocol)National Cancer Institute (NCI)Phase 2
A Study of Oral Lorlatinib in Patients With Relapsed ALK Positive LymphomaPfizerPhase 2

See all PF-06463922 clinical trials

Clinical Trial Summary for PF-06463922

Top disease conditions for PF-06463922
Top clinical trial sponsors for PF-06463922

See all PF-06463922 clinical trials

US Patents for PF-06463922

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
PF-06463922   Start Trial Substituted macrocycles useful as kinases inhibitors and methods of use thereof Teligene Ltd. (Suzhou, CN)   Start Trial
PF-06463922   Start Trial Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor Novartis AG (Basel, CH) The Trustees of the University of Pennsylvania (Philadelphia, PA)   Start Trial
PF-06463922   Start Trial CD20 therapies, CD22 therapies, and combination therapies with a CD19 chimeric antigen receptor (CAR)-expressing cell Novartis AG (Basel, CH) The Trustees of the University of Pennsylvania (Philadelphia, PA)   Start Trial
PF-06463922   Start Trial Treatment of cancer using anti-CD19 Chimeric Antigen Receptor The Trustees of the University of Pennsylvania (Philadelphia, PA) Novartis AG (Basel, CH)   Start Trial
PF-06463922   Start Trial Crystalline form of lorlatinib free base Pfizer Inc. (New York, NY)   Start Trial
PF-06463922   Start Trial Macrocyclic derivatives for the treatment of diseases Pfizer Inc. (New York, NY)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for PF-06463922

Drugname Country Document Number Estimated Expiration Related US Patent
PF-06463922 China 107207528 2034-08-20   Start Trial
PF-06463922 European Patent Office 3183256 2034-08-20   Start Trial
PF-06463922 Japan 2017525716 2034-08-20   Start Trial
PF-06463922 Argentina 102035 2034-07-21   Start Trial
PF-06463922 Australia 2015292744 2034-07-21   Start Trial
PF-06463922 Brazil 112017001183 2034-07-21   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

Medtronic
Merck
Colorcon
Boehringer Ingelheim
Dow
Mallinckrodt

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