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Drugs in Development Information for Lumacaftor
What is the drug development status for Lumacaftor?
Lumacaftor is an investigational drug.
There have been 33 clinical trials for Lumacaftor.
The most recent clinical trial was a Phase 3 trial, which was initiated on June 1st 2016.
The most common disease conditions in clinical trials are Cystic Fibrosis, Fibrosis, and Lung Diseases. The leading clinical trial sponsors are Vertex Pharmaceuticals Incorporated, National Heart, Lung, and Blood Institute (NHLBI), and Nivalis Therapeutics, Inc.
There are ninety-eight US patents protecting this investigational drug and nine hundred and seventeen international patents.
Summary for Lumacaftor
| US Patents | 98 |
| International Patents | 917 |
| US Patent Applications | 207 |
| WIPO Patent Applications | 91 |
| Japanese Patent Applications | 1 |
| Clinical Trial Progress | Phase 3 (2016-06-01) |
| Vendors | 81 |
Recent Clinical Trials for Lumacaftor
| Title | Sponsor | Phase |
|---|---|---|
| Validation of Respiratory Epithelial Functional Assessment to Predict Clinical Efficacy of Orkambi®. | Assistance Publique - Hôpitaux de Paris | N/A |
| Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240 | University of North Carolina | Early Phase 1 |
| Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240 | University of Miami | Early Phase 1 |
Clinical Trial Summary for Lumacaftor
Top disease conditions for Lumacaftor
Top clinical trial sponsors for Lumacaftor
US Patents for Lumacaftor
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| Lumacaftor | Start Trial | Compounds, compositions, and methods for increasing CFTR activity | Proteostasis Therapeutics, Inc. (Boston, MA) | Start Trial |
| Lumacaftor | Start Trial | Modulators of ATP-binding cassette transporters | Vertex Pharmaceuticals Incorporated (Boston, MA) | Start Trial |
| Lumacaftor | Start Trial | Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid and administration thereof | Vertex Pharmaceuticals Incorporated (Boston, MA) | Start Trial |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for Lumacaftor
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| Lumacaftor | Australia | 2015229117 | 2034-03-13 | Start Trial |
| Lumacaftor | Canada | 2942387 | 2034-03-13 | Start Trial |
| Lumacaftor | European Patent Office | 3116870 | 2034-03-13 | Start Trial |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
