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Drugs in Development Information for LDK378
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What is the drug development status for LDK378?
LDK378 is an investigational drug.
There have been 29 clinical trials for LDK378.
The most recent clinical trial was a Phase 2 trial, which was initiated on December 1st 2015.
The most common disease conditions in clinical trials are Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, and Lymphoma. The leading clinical trial sponsors are Novartis Pharmaceuticals, National Cancer Institute (NCI), and Novartis.
There are thirty-nine US patents protecting this investigational drug and seven hundred and seventy-nine international patents.
Summary for LDK378
US Patents | 39 |
International Patents | 779 |
US Patent Applications | 95 |
WIPO Patent Applications | 844 |
Japanese Patent Applications | 0 |
Clinical Trial Progress | Phase 2 (2015-12-01) |
Vendors | 75 |
Recent Clinical Trials for LDK378
Title | Sponsor | Phase |
---|---|---|
Biomarker/ALK Inhibitor Combinations in Treating Patients With Stage IV ALK Positive Non-Small Cell Lung Cancer (The NCI-NRG ALK Master Protocol) | National Cancer Institute (NCI) | Phase 2 |
A Study of LDK378 in Patients With Non-small Cell Lung Cancer Harboring ROS1 Rearrangement | Yonsei University | Phase 2 |
Ceritinib With Brentuximab Vedotin in Treating Patients With ALK-Positive Anaplastic Large Cell Lymphoma | National Cancer Institute (NCI) | Phase 1/Phase 2 |
Clinical Trial Summary for LDK378
Top disease conditions for LDK378
Top clinical trial sponsors for LDK378
US Patents for LDK378
Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
---|---|---|---|---|
LDK378 | Start Trial | Polycyclic inhibitor of anaplastic lymphoma kinase | XUANZHU PHARMA CO., LTD. (Jinan, Shandong Province, CN) | Start Trial |
LDK378 | Start Trial | Hydrate of 2-isopropoxy-5-methyl-4-(piperidin-4-yl) aniline dihydrochloride, preparation method and use of the same | 2Y-CHEM, LTD. (Shanghai, CN) | Start Trial |
LDK378 | Start Trial | Inhibitors of ACK1/TNK2 tyrosine kinase | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, FL) | Start Trial |
LDK378 | Start Trial | Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor | Novartis AG (Basel, CH) The Trustees of the University of Pennsylvania (Philadelphia, PA) | Start Trial |
LDK378 | Start Trial | CD20 therapies, CD22 therapies, and combination therapies with a CD19 chimeric antigen receptor (CAR)-expressing cell | Novartis AG (Basel, CH) The Trustees of the University of Pennsylvania (Philadelphia, PA) | Start Trial |
LDK378 | Start Trial | Treatment of cancer using anti-CD19 Chimeric Antigen Receptor | The Trustees of the University of Pennsylvania (Philadelphia, PA) Novartis AG (Basel, CH) | Start Trial |
LDK378 | Start Trial | Compositions and methods for activating "stimulator of interferon gene"--dependent signalling | ADURO BIOTECH, INC. (Berkeley, CA) | Start Trial |
>Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for LDK378
Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
---|---|---|---|---|
LDK378 | China | CN107108586 | 2034-09-29 | Start Trial |
LDK378 | European Patent Office | EP3202765 | 2034-09-29 | Start Trial |
LDK378 | Japan | JP2017530139 | 2034-09-29 | Start Trial |
LDK378 | Japan | JP6554538 | 2034-09-29 | Start Trial |
LDK378 | South Korea | KR101909404 | 2034-09-29 | Start Trial |
LDK378 | South Korea | KR20170055555 | 2034-09-29 | Start Trial |
LDK378 | World Intellectual Property Organization (WIPO) | WO2016050171 | 2034-09-29 | Start Trial |
>Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |