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Last Updated: June 18, 2024

Investigational Drug Information for Islatravir


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What is the development status for investigational drug Islatravir?

Islatravir is an investigational drug.

There have been 23 clinical trials for Islatravir. The most recent clinical trial was a Phase 1 trial, which was initiated on February 28th 2020.

The most common disease conditions in clinical trials are HIV Infections, Infections, and Infection. The leading clinical trial sponsors are Merck Sharp & Dohme Corp., Merck Sharp & Dohme LLC, and Gilead Sciences.

There are seven US patents protecting this investigational drug and two hundred and seventy-six international patents.

Recent Clinical Trials for Islatravir
TitleSponsorPhase
A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)Merck Sharp & Dohme LLCPhase 3
DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)Merck Sharp & Dohme LLCPhase 3
A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-052)Merck Sharp & Dohme LLCPhase 3

See all Islatravir clinical trials

Clinical Trial Summary for Islatravir

Top disease conditions for Islatravir
Top clinical trial sponsors for Islatravir

See all Islatravir clinical trials

US Patents for Islatravir

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Islatravir ⤷  Sign Up Therapeutic compounds Gilead Sciences, Inc. (Foster City, CA) ⤷  Sign Up
Islatravir ⤷  Sign Up Substituted spiropyrido[1,2-a]pyrazine derivative and medicinal use thereof as HIV integrase inhibitor JAPAN TOBACCO INC. (Tokyo, JP) ⤷  Sign Up
Islatravir ⤷  Sign Up Macroheterocyclic nucleoside derivatives and their analogues, production and use thereof ⤷  Sign Up
Islatravir ⤷  Sign Up Antiviral prodrugs of tenofovir Merck Sharp & Dohme Corp. (Rahway, NJ) Idenix Pharmaceuticals LLC. (Cambridge, MA) ⤷  Sign Up
Islatravir ⤷  Sign Up Therapeutic compounds Gilead Sciences, Inc. (Foster City, CA) ⤷  Sign Up
Islatravir ⤷  Sign Up Solid forms of an HIV capsid inhibitor Gilead Sciences, Inc. ⤷  Sign Up
Islatravir ⤷  Sign Up Potent chimeric NRTI-NNRTI bifunctional inhibitors of HIV-1 reverse transcriptase Yale University (New Haven, CT) University of Cape Town (Cape Town, ZA) ⤷  Sign Up
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Islatravir

Drugname Country Document Number Estimated Expiration Related US Patent
Islatravir Argentina AR109364 2036-08-19 ⤷  Sign Up
Islatravir Argentina AR115865 2036-08-19 ⤷  Sign Up
Islatravir Argentina AR117709 2036-08-19 ⤷  Sign Up
Islatravir Australia AU2017312102 2036-08-19 ⤷  Sign Up
Islatravir Australia AU2020202331 2036-08-19 ⤷  Sign Up
Islatravir Australia AU2021221855 2036-08-19 ⤷  Sign Up
Islatravir Brazil BR112018071678 2036-08-19 ⤷  Sign Up
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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