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Last Updated: February 26, 2021

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Drugs in Development Information for Indoximod

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What is the drug development status for Indoximod?

Indoximod is an investigational drug.

There have been 14 clinical trials for Indoximod. The most recent clinical trial was a Phase 1 trial, which was initiated on October 1st 2017.

The most common disease conditions in clinical trials are Brain Neoplasms, Glioma, and Glioblastoma. The leading clinical trial sponsors are NewLink Genetics Corporation, National Cancer Institute (NCI), and Emory University.

There are sixty-nine US patents protecting this investigational drug and six hundred and eighty-six international patents.

Recent Clinical Trials for Indoximod
TitleSponsorPhase
Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGEmory UniversityPhase 2
Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGTheodore S. JohnsonPhase 2
A 2-part, Phase 1, Randomized Study in Health Men to: 1) Evaluate the Pharmacokinetics and Safety of Different Doses Indoximod HCL (Salt) Tablets and; 2) Compare the Proportion of 2 Different Formulations of Indoximod That Enters the Circulation andNewLink Genetics CorporationEarly Phase 1

See all Indoximod clinical trials

Clinical Trial Summary for Indoximod

Top disease conditions for Indoximod
Top clinical trial sponsors for Indoximod

See all Indoximod clinical trials

US Patents for Indoximod

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Indoximod   Start Trial Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus Seattle Genetics, Inc. (Bothell, WA)   Start Trial
Indoximod   Start Trial Antibodies to ICOS Jounce Therapeutics, Inc. (Cambridge, MA)   Start Trial
Indoximod   Start Trial Tank-binding kinase inhibitor compounds Gilead Sciences, Inc. (Foster City, CA)   Start Trial
Indoximod   Start Trial COX-2-targeting, platinum-containing conjugates and their use in the treatment of tumors and cancers REILEY PHARMACEUTICALS, INC. (San Jose, CA)   Start Trial
Indoximod   Start Trial Carbidopa for the treatment of cancer Texas Tech University System (Lubbock, TX)   Start Trial
Indoximod   Start Trial Tumor associated vaccines and compositions for disrupting tumor-derived immunosuppression for use in combination cancer immunotherapy CITY OF HOPE (Duarte, CA)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Indoximod

Drugname Country Document Number Estimated Expiration Related US Patent
Indoximod Australia AU2006269422 2025-07-07   Start Trial
Indoximod Canada CA2614436 2025-07-07   Start Trial
Indoximod European Patent Office EP1917020 2025-07-07   Start Trial
Indoximod European Patent Office EP2722051 2025-07-07   Start Trial
Indoximod European Patent Office EP3498289 2025-07-07   Start Trial
Indoximod Spain ES2585357 2025-07-07   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

McKinsey
Baxter
Dow
Colorcon
Express Scripts
Merck

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