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Last Updated: July 4, 2020

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Drugs in Development Information for Indoximod


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What is the drug development status for Indoximod?

Indoximod is an investigational drug.

There have been 14 clinical trials for Indoximod. The most recent clinical trial was a Phase 1 trial, which was initiated on October 1st 2017.

The most common disease conditions in clinical trials are Glioma, Glioblastoma, and Brain Neoplasms. The leading clinical trial sponsors are NewLink Genetics Corporation, National Cancer Institute (NCI), and Theodore S. Johnson.

There are fifty-seven US patents protecting this investigational drug and four hundred and eighty-one international patents.

Recent Clinical Trials for Indoximod
TitleSponsorPhase
Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGEmory UniversityPhase 2
Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGTheodore S. JohnsonPhase 2
A 2-part, Phase 1, Randomized Study in Health Men to: 1) Evaluate the Pharmacokinetics and Safety of Different Doses Indoximod HCL (Salt) Tablets and; 2) Compare the Proportion of 2 Different Formulations of Indoximod That Enters the Circulation andNewLink Genetics CorporationEarly Phase 1

See all Indoximod clinical trials

Clinical Trial Summary for Indoximod

Top disease conditions for Indoximod
Top clinical trial sponsors for Indoximod

See all Indoximod clinical trials

US Patents for Indoximod

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Indoximod   Start Trial Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus Seattle Genetics, Inc. (Bothell, WA)   Start Trial
Indoximod   Start Trial Antibodies to ICOS Jounce Therapeutics, Inc. (Cambridge, MA)   Start Trial
Indoximod   Start Trial Tank-binding kinase inhibitor compounds Gilead Sciences, Inc. (Foster City, CA)   Start Trial
Indoximod   Start Trial COX-2-targeting, platinum-containing conjugates and their use in the treatment of tumors and cancers REILEY PHARMACEUTICALS, INC. (San Jose, CA)   Start Trial
Indoximod   Start Trial Carbidopa for the treatment of cancer Texas Tech University System (Lubbock, TX)   Start Trial
Indoximod   Start Trial Tumor associated vaccines and compositions for disrupting tumor-derived immunosuppression for use in combination cancer immunotherapy CITY OF HOPE (Duarte, CA)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Indoximod

Drugname Country Document Number Estimated Expiration Related US Patent
Indoximod Australia 2006269422 2025-07-07   Start Trial
Indoximod Canada 2614436 2025-07-07   Start Trial
Indoximod European Patent Office 1917020 2025-07-07   Start Trial
Indoximod European Patent Office 2722051 2025-07-07   Start Trial
Indoximod European Patent Office 3498289 2025-07-07   Start Trial
Indoximod Spain 2585357 2025-07-07   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

McKinsey
Baxter
Dow
Colorcon
Express Scripts
Merck

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