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Investigational Drug Information for Evobrutinib
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What is the development status for investigational drug Evobrutinib?
Evobrutinib is an investigational drug.
There have been 17 clinical trials for Evobrutinib.
The most recent clinical trial was a Phase 2 trial, which was initiated on August 26th 2019.
The most common disease conditions in clinical trials are Sclerosis, Multiple Sclerosis, and Multiple Sclerosis, Relapsing-Remitting. The leading clinical trial sponsors are Merck KGaA, Darmstadt, Germany, EMD Serono Research & Development Institute, Inc., and Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany.
There are nine US patents protecting this investigational drug and one hundred and twenty-three international patents.
Summary for Evobrutinib
| US Patents | 9 |
| International Patents | 123 |
| US Patent Applications | 72 |
| WIPO Patent Applications | 87 |
| Japanese Patent Applications | 17 |
| Clinical Trial Progress | Phase 2 (2019-08-26) |
| Vendors | 27 |
Recent Clinical Trials for Evobrutinib
| Title | Sponsor | Phase |
|---|---|---|
| Drug-Drug Interaction Study of Evobrutinib and Transporter Substrates | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | Phase 1 |
| Drug-drug Interaction Study of Evobrutinib With Midazolam in Healthy Participants | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | Phase 1 |
| Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | Phase 1 |
Clinical Trial Summary for Evobrutinib
Top disease conditions for Evobrutinib
Top clinical trial sponsors for Evobrutinib
US Patents for Evobrutinib
| Drugname | Patent Number | Patent Title | Patent Assignee | Estimated Expiration |
|---|---|---|---|---|
| Evobrutinib | ⤷ Try it Free | Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity | Merck Patent GmbH (Darmstadt, DE) | ⤷ Try it Free |
| Evobrutinib | ⤷ Try it Free | Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity | Merck Patent GmbH (Darmstadt, DE) | ⤷ Try it Free |
| Evobrutinib | ⤷ Try it Free | Crystalline forms of 1-(4-{[6-amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino]-methyl}-piperidi- n-1-yl)-propenone | Merck Patent GmbH (Darmstadt, DE) | ⤷ Try it Free |
| Evobrutinib | ⤷ Try it Free | Crystalline forms of 1-(4-{[6-amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino]-methyl}-piperidi- n-1-yl)-propenone | Merck Patent GmbH (Darmstadt, DE) | ⤷ Try it Free |
| Evobrutinib | ⤷ Try it Free | PD-1/PD-L1 inhibitors | Gilead Sciences, Inc. (Foster City, CA) | ⤷ Try it Free |
| >Drugname | >Patent Number | >Patent Title | >Patent Assignee | >Estimated Expiration |
International Patents for Evobrutinib
| Drugname | Country | Document Number | Estimated Expiration | Related US Patent |
|---|---|---|---|---|
| Evobrutinib | Australia | AU2012267491 | 2031-06-10 | ⤷ Try it Free |
| Evobrutinib | Australia | AU2017235978 | 2031-06-10 | ⤷ Try it Free |
| Evobrutinib | Brazil | BR112013030442 | 2031-06-10 | ⤷ Try it Free |
| Evobrutinib | Canada | CA2833771 | 2031-06-10 | ⤷ Try it Free |
| Evobrutinib | China | CN103814016 | 2031-06-10 | ⤷ Try it Free |
| >Drugname | >Country | >Document Number | >Estimated Expiration | >Related US Patent |
