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Last Updated: November 11, 2019

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Drugs in Development Information for CC-223

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What is the development status for investigational drug CC-223?

CC-223 is an investigational drug.

There have been 5 clinical trials for CC-223. The most recent clinical trial was a Phase 1 trial, which was initiated on July 1st 2010.

The most common disease conditions in clinical trials are Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, and Lymphoma. The leading clinical trial sponsors are Celgene Corporation and [disabled in preview].

There are thirty-three US patents protecting this investigational drug and three hundred and thirty-seven international patents.

Recent Clinical Trials for CC-223
TitleSponsorPhase
Novel Combinations of CC-122, CC-223, CC-292, and Rituximab in Diffuse Large B-cell LymphomaCelgene CorporationPhase 1
CC-223 and Ketoconazole Drug-Drug Interaction StudyCelgene CorporationPhase 1
A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult SubjectsCelgene CorporationPhase 1

See all CC-223 clinical trials

Clinical Trial Summary for CC-223

Top disease conditions for CC-223
Top clinical trial sponsors for CC-223

See all CC-223 clinical trials

US Patents for CC-223

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
CC-223   Start Trial Methods for treating cancer using TOR kinase inhibitor combination therapy comprising administering substituted pyrazino[2,3-b]pyrazines Signal Pharmaceuticals, LLC (San Diego, CA)   Start Trial
CC-223   Start Trial Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(trans)-4-methoxycyclohexyl)-3- ,4-dihydropyrazino [2,3-b]pyrazin-2(1H)-one, a solid form thereof and methods of their use Signal Pharmaceuticals, LLC (San Diego, CA)   Start Trial
CC-223   Start Trial Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors Signal Pharmaceuticals, LLC (San Diego, CA)   Start Trial
CC-223   Start Trial Treatment of cancer with dihydropyrazino-pyrazines Signal Pharmaceuticals, LLC (San Diego, CA)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for CC-223

Drugname Country Document Number Estimated Expiration Related US Patent
CC-223 European Patent Office 3131552 2034-04-16   Start Trial
CC-223 Japan 2017514806 2034-04-16   Start Trial
CC-223 Japan 2019070012 2034-04-16   Start Trial
CC-223 New Zealand 629860 2034-04-16   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Moodys
Colorcon
Medtronic
Baxter
McKinsey

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