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Last Updated: November 21, 2019

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Drugs in Development Information for Birinapant

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What is the development status for investigational drug Birinapant?

Birinapant is an investigational drug.

There have been 12 clinical trials for Birinapant. The most recent clinical trial was a Phase 2 trial, which was initiated on January 1st 2017.

The most common disease conditions in clinical trials are Fallopian Tube Neoplasms, Ovarian Neoplasms, and Neoplasms. The leading clinical trial sponsors are TetraLogic Pharmaceuticals, National Cancer Institute (NCI), and Jonsson Comprehensive Cancer Center.

There are four US patents protecting this investigational drug and thirty-one international patents.

Recent Clinical Trials for Birinapant
TitleSponsorPhase
Birinapant and Intensity Modulated Re-Irradiation Therapy for Local-Regionally Recurrent Head and Neck Squamous Cell CarcinomaNational Cancer Institute (NCI)Phase 1
Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurrent Head and Neck Squamous Cell CarcinomaNational Cancer Institute (NCI)Phase 1
Dose-escalation Study of Birinapant and Pembrolizumab in Solid TumorsMerck Sharp & Dohme Corp.Phase 1/Phase 2

See all Birinapant clinical trials

Clinical Trial Summary for Birinapant

Top disease conditions for Birinapant
Top clinical trial sponsors for Birinapant

See all Birinapant clinical trials

US Patents for Birinapant

Drugname Patent Number Patent Title Patent Assignee Estimated Expiration
Birinapant   Start Trial SMAC Mimetic TetraLogic Birinapant UK Ltd. (Birmingham, GB)   Start Trial
Birinapant   Start Trial SMAC mimetic Medivir AB (Huddinge, SE)   Start Trial
Birinapant   Start Trial 2-(1H-indol-3-ylmethyl)-pyrrolidine dimer as a SMAC mimetic TetraLogic Pharmaceuticals Corp. (Malvern, PA)   Start Trial
Birinapant   Start Trial SMAC mimetic for treating myelodysplastic syndromes TetraLogic Pharmaceuticals Corporation (Malvern, PA)   Start Trial
>Drugname >Patent Number >Patent Title >Patent Assignee >Estimated Expiration

International Patents for Birinapant

Drugname Country Document Number Estimated Expiration Related US Patent
Birinapant African Regional IP Organization (ARIPO) 3619 2029-07-02   Start Trial
Birinapant Argentina 077629 2029-07-02   Start Trial
Birinapant Australia 2010266525 2029-07-02   Start Trial
Birinapant Brazil PI1013958 2029-07-02   Start Trial
Birinapant Canada 2766162 2029-07-02   Start Trial
Birinapant China 102471275 2029-07-02   Start Trial
Birinapant Colombia 6480975 2029-07-02   Start Trial
>Drugname >Country >Document Number >Estimated Expiration >Related US Patent

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
Mallinckrodt
AstraZeneca
Harvard Business School
Boehringer Ingelheim
Medtronic

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