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AF-219 is an investigational drug.
There have been 14 clinical trials for AF-219. The most recent clinical trial was a Phase 2 trial, which was initiated on August 1st 2011.
The most common disease conditions in clinical trials are Cough, Pulmonary Fibrosis, and Idiopathic Pulmonary Fibrosis. The leading clinical trial sponsors are Afferent Pharmaceuticals, Inc., Celerion, and [disabled in preview].
There are fourteen US patents protecting this investigational drug and one hundred and twenty-seven international patents.
Recent Clinical Trials for AF-219
|A Multiple-Dose Pharmacokinetics Study of Three AF-219 Formulations||Afferent Pharmaceuticals, Inc.||Phase 1|
|A 12-Week Study in Subjects With Refractory Chronic Cough||Afferent Pharmaceuticals, Inc.||Phase 2|
|An 8-Week Refractory Chronic Cough Study||Afferent Pharmaceuticals, Inc.||Phase 2|
Top disease conditions for AF-219
Top clinical trial sponsors for AF-219
|Drugname||Patent Number||Patent Title||Patent Assignee||Estimated Expiration|
|AF-219||Start Trial||Methods and compositions for treating diseases and conditions||Afferent Pharmaceuticals, Inc. (San Mateo, CA)||Start Trial|
|AF-219||Start Trial||Substituted pyrimidines for treatment of chronic cough, neuronal hypersensitivity underlying chronic cough, neuronal hypersensitivity underlying sub-acute cough and neuronal hypersensitivity underlying acute cough||Afferent Pharmaceuticals, Inc. (San Mateo, CA)||Start Trial|
|AF-219||Start Trial||Diaminopyrimidines as P2X.sub.3 and P2X.sub.2/3 antagonists||Roche Palo Alto LLC (Palo Alto, CA)||Start Trial|
|AF-219||Start Trial||Process for synthesis of phenoxy diaminopyrimidine derivatives||Roche Palo Alto LLC (Palo Alto, CA)||Start Trial|
|AF-219||Start Trial||Methods of using diaminopyrimidine P2X.sub.3 and P2X.sub.2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases||Roche Palo Alto LLC (Palo Alto, CA)||Start Trial|
|AF-219||Start Trial||Methods of using diaminopyrimidine as P2X.sub.3 and P2X2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases||Roche Palo Alto LLC (Palo Alto, CA)||Start Trial|
|>Drugname||>Patent Number||>Patent Title||>Patent Assignee||>Estimated Expiration|
|Drugname||Country||Document Number||Estimated Expiration||Related US Patent|
|AF-219||European Patent Office||3164132||2034-07-03||Start Trial|
|AF-219||World Intellectual Property Organization (WIPO)||2016004358||2034-07-03||Start Trial|
|>Drugname||>Country||>Document Number||>Estimated Expiration||>Related US Patent|