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Last Updated: December 30, 2025

CLINICAL TRIALS PROFILE FOR VABORBACTAM

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Clinical Trials for Vaborbactam

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT02166476 ↗	Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP	Completed	Department of Health and Human Services	Phase 3	Meropenem-vaborbactam is being compared to piperacillin-tazobactam in the treatment of adults with complicated urinary tract infection (cUTI) or acute pyelonephritis (AP).
NCT02166476 ↗	Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP	Completed	Melinta Therapeutics, Inc.	Phase 3	Meropenem-vaborbactam is being compared to piperacillin-tazobactam in the treatment of adults with complicated urinary tract infection (cUTI) or acute pyelonephritis (AP).
NCT02166476 ↗	Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP	Completed	Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company)	Phase 3	Meropenem-vaborbactam is being compared to piperacillin-tazobactam in the treatment of adults with complicated urinary tract infection (cUTI) or acute pyelonephritis (AP).
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Vaborbactam

Condition Name

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Condition Name
Intervention	Trials
Acute Pyelonephritis	3
Ventilator-Associated Bacterial Pneumonia	2
Hospital Acquired Bacterial Pneumonia	2
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Condition MeSH

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Condition MeSH
Intervention	Trials
Infections	3
Infection	3
Urinary Tract Infections	2
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Clinical Trial Locations for Vaborbactam

Trials by Country

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Trials by Country
Location	Trials
United States	31
Spain	4
Brazil	4
Italy	3
Poland	3
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Trials by US State

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Trials by US State
Location	Trials
New Jersey	3
Illinois	3
California	3
Nebraska	2
Arkansas	2
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Clinical Trial Progress for Vaborbactam

Clinical Trial Phase

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Clinical Trial Phase
Clinical Trial Phase	Trials
PHASE4	1
PHASE2	3
Phase 3	3
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Clinical Trial Status

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Clinical Trial Status
Clinical Trial Phase	Trials
Recruiting	5
Completed	3
Withdrawn	1
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Clinical Trial Sponsors for Vaborbactam

Sponsor Name

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Sponsor Name
Sponsor	Trials
Department of Health and Human Services	3
Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company)	3
Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.)	3
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Sponsor Type

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Sponsor Type
Sponsor	Trials
Industry	10
OTHER	4
U.S. Fed	4
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