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Last Updated: September 22, 2020

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CLINICAL TRIALS PROFILE FOR VABORBACTAM

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Clinical Trials for Vaborbactam

Trial ID Title Status Sponsor Phase Summary
NCT02166476 Efficacy, Safety, Tolerability of Carbavance Compared to Piperacillin/Tazobactam in Complicated Urinary Tract Infections (cUTIs), Including Acute Pyelonephritis (AP), in Adults Completed Department of Health and Human Services Phase 3 Carbavance, (meropenem/vaborbactam) is being compared to piperacillin/tazobactam in the treatment of adults with cUTIs or AP
NCT02166476 Efficacy, Safety, Tolerability of Carbavance Compared to Piperacillin/Tazobactam in Complicated Urinary Tract Infections (cUTIs), Including Acute Pyelonephritis (AP), in Adults Completed Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company) Phase 3 Carbavance, (meropenem/vaborbactam) is being compared to piperacillin/tazobactam in the treatment of adults with cUTIs or AP
NCT02168946 Efficacy, Safety, Tolerability of Carbavance Compared to Best Available Therapy in Serious Infections Due to Carbapenem Resistant Enterobacteriaceae, in Adults Recruiting Department of Health and Human Services Phase 3 Carbavance™, (meropenem/vaborbactam) is being compared to the Best Available Therapy in the treatment of adults with selected serious infections due to Carbapenem Resistant Enterobacteriaceae
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Vaborbactam

Condition Name

Condition Name for
Intervention Trials
Urinary Tract Infection Complicated 2
Acute Pyelonephritis 2
Ventilator-Associated Bacterial Pneumonia 2
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Condition MeSH

Condition MeSH for
Intervention Trials
Infection 3
Urinary Tract Infections 2
Pyelonephritis 2
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Clinical Trial Locations for Vaborbactam

Trials by Country

Trials by Country for
Location Trials
United States 26
Brazil 4
Greece 2
Spain 2
Italy 2
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Trials by US State

Trials by US State for
Location Trials
New York 2
Illinois 2
Georgia 2
Florida 2
California 2
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Clinical Trial Progress for Vaborbactam

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 3
Phase 1 2
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Recruiting 3
Withdrawn 1
Completed 1
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Clinical Trial Sponsors for Vaborbactam

Sponsor Name

Sponsor Name for
Sponsor Trials
Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company) 3
Department of Health and Human Services 3
Melinta Therapeutics, Inc. 1
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Sponsor Type

Sponsor Type for
Sponsor Trials
Industry 5
U.S. Fed 4
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Serving leading biopharmaceutical companies globally:

Dow
McKinsey
Boehringer Ingelheim
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Merck

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