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Last Updated: April 1, 2026

CLINICAL TRIALS PROFILE FOR VNRX-7145


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Clinical Trials for VNRX-7145

Trial ID Title Status Sponsor Phase Summary
NCT04243863 ↗ VNRX-7145 SAD/MAD Safety and PK in Healthy Adult Volunteers Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 This is a 2-part, first-in-human dose-ranging study to evaluate the safety and pharmacokinetics of escalating doses of VNRX-7145. In part 1, subjects will receive a single dose of VNRX-7145; in part 2 subjects will receive multiple doses of VNRX-7145 for 10 days.
NCT04243863 ↗ VNRX-7145 SAD/MAD Safety and PK in Healthy Adult Volunteers Completed Venatorx Pharmaceuticals, Inc. Phase 1 This is a 2-part, first-in-human dose-ranging study to evaluate the safety and pharmacokinetics of escalating doses of VNRX-7145. In part 1, subjects will receive a single dose of VNRX-7145; in part 2 subjects will receive multiple doses of VNRX-7145 for 10 days.
NCT04877379 ↗ VNRX-7145 Drug-Drug Interaction in Healthy Adult Volunteers Recruiting National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 This study will provide an initial assessment of the safety and PK of VNRX-7145 and VNRX-5024 (ceftibuten) when administered as single agents and with co-administration in a single dose cross-over design in Part 1. In Part 2, subjects will receive 500 mg of VNRX-7145 or matching placebo q8h for 10 days. VNRX-7145 and VNRX-5024 (ceftibuten) will be administered every 8 hours (q8h) for 10 days at 2 dose levels of VNRX-7145 in Part 3.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for VNRX-7145

Condition Name

Condition Name
Intervention Trials
Pharmacokinetics 2
Healthy Subjects 1
Healthy Volunteers 1
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Condition MeSH

Condition MeSH
Intervention Trials
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Clinical Trial Locations for VNRX-7145

Trials by Country

Trials by Country
Location Trials
United States 4
Netherlands 1
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Trials by US State

Trials by US State
Location Trials
Kansas 1
Minnesota 1
Florida 1
Texas 1
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Clinical Trial Progress for VNRX-7145

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase Trials
Phase 1 4
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Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase Trials
Not yet recruiting 2
Completed 1
Recruiting 1
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Clinical Trial Sponsors for VNRX-7145

Sponsor Name

Sponsor Name
Sponsor Trials
National Institute of Allergy and Infectious Diseases (NIAID) 4
Venatorx Pharmaceuticals, Inc. 4
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Sponsor Type

Sponsor Type
Sponsor Trials
NIH 4
Industry 4
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