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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR TRIAPINE


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Clinical Trials for Triapine

Trial ID Title Status Sponsor Phase Summary
NCT00004213 ↗ 3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone in Treating Patients With Solid Tumors Completed Vion Pharmaceuticals Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone in treating patients who have solid tumors that have not responded to previous treatment.
NCT00006218 ↗ 3-AP in Treating Patients With Advanced Cancer Completed Vion Pharmaceuticals Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of 3-AP in treating patients who have advanced cancer.
NCT00016874 ↗ 3-AP Plus Cisplatin and Paclitaxel in Treating Patients With Advanced or Metastatic Cancer Completed Vion Pharmaceuticals Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining 3-AP, cisplatin, and paclitaxel in treating patients who have advanced or metastatic cancer.
NCT00024323 ↗ Combination Chemotherapy in Treating Patients With Advanced Cancer Completed Vion Pharmaceuticals Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining 3-AP with cisplatin in treating patients who have advanced cancer.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Triapine

Condition Name

Condition Name for
Intervention Trials
Unspecified Adult Solid Tumor, Protocol Specific 8
Stage IVA Cervical Cancer 5
Stage IIIB Cervical Cancer 4
Stage IIB Cervical Cancer 4
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Condition MeSH

Condition MeSH for
Intervention Trials
Adenocarcinoma 7
Leukemia 5
Vaginal Neoplasms 5
Uterine Cervical Neoplasms 5
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Clinical Trial Locations for Triapine

Trials by Country

Trials by Country for
Location Trials
United States 141
Canada 6
Puerto Rico 2
Australia 2
Netherlands 1
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Trials by US State

Trials by US State for
Location Trials
Ohio 7
Illinois 7
Minnesota 7
California 6
Pennsylvania 6
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Clinical Trial Progress for Triapine

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 2
Phase 2 15
Phase 1 15
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Completed 26
Recruiting 5
Terminated 1
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Clinical Trial Sponsors for Triapine

Sponsor Name

Sponsor Name for
Sponsor Trials
National Cancer Institute (NCI) 25
Vion Pharmaceuticals 8
NRG Oncology 2
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Sponsor Type

Sponsor Type for
Sponsor Trials
NIH 25
Industry 8
Other 7
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