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Last Updated: April 25, 2024

CLINICAL TRIALS PROFILE FOR TESETAXEL


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Clinical Trials for Tesetaxel

Trial ID Title Status Sponsor Phase Summary
NCT01064713 ↗ Phase II Study of Tesetaxel in Metastatic Melanoma Completed Genta Incorporated Phase 2 The goal of this clinical research study is to learn if tesetaxel can help to control metastatic melanoma. The safety of this drug will also be studied.
NCT01064713 ↗ Phase II Study of Tesetaxel in Metastatic Melanoma Completed M.D. Anderson Cancer Center Phase 2 The goal of this clinical research study is to learn if tesetaxel can help to control metastatic melanoma. The safety of this drug will also be studied.
NCT01092585 ↗ Tesetaxel as Second-line Therapy for Patients With Advanced Melanoma and Normal Serum LDH Unknown status Genta Incorporated Phase 2 Tesetaxel is an orally administered chemotherapy agent of the taxane class. This study is being undertaken to evaluate the efficacy and safety of tesetaxel administered as second-line therapy to patients with advanced melanoma and normal serum lactate dehydrogenase (LDH).
NCT01095120 ↗ Tesetaxel as Second-line Therapy for Patients With Advanced Gastric Cancer Unknown status Genta Incorporated Phase 2 Tesetaxel is an orally administered chemotherapy agent of the taxane class. This study is being undertaken to evaluate the efficacy and safety of tesetaxel administered as second-line therapy to patients with advanced gastric cancer.
NCT01170975 ↗ Effects of Food on the Pharmacokinetics of Tesetaxel 10 mg Capsules Completed Genta Incorporated Phase 1 This study explores the effects of food (a high-fat meal) on the pharmacokinetics of tesetaxel.
NCT01215877 ↗ Tesetaxel for Previously Treated Patients With Bladder Cancer Unknown status Genta Incorporated Phase 2 The intravenously administered taxanes, docetaxel and paclitaxel, alone and in combination with other chemotherapy agents are active in patients with advanced and metastatic bladder cancer, and agents of this class are a promising treatment option for some patients. Tesetaxel is an orally administered taxane that is in development as treatment for subjects with advanced cancers. This study is being conducted to determine the efficacy and safety of tesetaxel administered to patients previously treated with chemotherapy for progressive metastatic transitional cell carcinoma of the urothelium.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Tesetaxel

Condition Name

Condition Name for
Intervention Trials
Breast Cancer 3
Gastric Carcinoma 2
Advanced Solid Tumors 2
Carcinoma, Transitional Cell 1
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Condition MeSH

Condition MeSH for
Intervention Trials
Breast Neoplasms 5
Stomach Neoplasms 3
Neoplasms 3
Melanoma 2
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Clinical Trial Locations for Tesetaxel

Trials by Country

Trials by Country for
Location Trials
United States 65
Canada 6
Australia 6
Korea, Republic of 5
Germany 5
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Trials by US State

Trials by US State for
Location Trials
Texas 9
New York 6
Tennessee 6
Florida 3
Michigan 3
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Clinical Trial Progress for Tesetaxel

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 1
Phase 2 10
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Unknown status 10
Terminated 4
Completed 2
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Clinical Trial Sponsors for Tesetaxel

Sponsor Name

Sponsor Name for
Sponsor Trials
Genta Incorporated 12
Odonate Therapeutics, Inc. 4
M.D. Anderson Cancer Center 1
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Sponsor Type

Sponsor Type for
Sponsor Trials
Industry 17
Other 1
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