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Last Updated: April 18, 2024

CLINICAL TRIALS PROFILE FOR TAVAPADON

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Clinical Trials for Tavapadon

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT04201093 ↗	Fixed-Dose Trial in Early Parkinson's Disease (PD)	Recruiting	Cerevel Therapeutics, LLC	Phase 3	The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early PD.
NCT04223193 ↗	Flexible-Dose Trial in Early Parkinson's Disease (PD)	Recruiting	Cerevel Therapeutics, LLC	Phase 3	The purpose of this study is to assess the efficacy, safety, tolerability and pharmacokinetics (PK) of flexible doses of tavapadon in participants with Parkinson's Disease.
NCT04241393 ↗	An Open-label Trial to Evaluate Mass Balance of Tavapadon at Steady State in Healthy Subjects	Completed	Cerevel Therapeutics, LLC	Phase 1	The purpose of this trial is to determine the absorption, metabolism, and excretion (AME) of [14C] tavapadon.
NCT04542499 ↗	Flexible-Dose, Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations	Recruiting	Cerevel Therapeutics, LLC	Phase 3	The purpose of this study is to assess the effect of tavapadon on the change from baseline in total daily hours of "on" time without troublesome dyskinesia in L-Dopa-treated participants with Parkinson's Disease (PD) who are experiencing motor fluctuations.
NCT04760769 ↗	Open-label Trial in Parkinson's Disease (PD)	Recruiting	Cerevel Therapeutics, LLC	Phase 3	The purpose of this study is to evaluate the safety and efficacy of long-term administration of flexible doses of tavapadon in participants with Parkinson's Disease.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Tavapadon

Condition Name

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Condition Name for
Intervention	Trials
Parkinson Disease	6
Healthy Subjects	1
Hepatic Impairment	1
Renal Impairment	1
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Condition MeSH

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Condition MeSH for
Intervention	Trials
Parkinson Disease	6
Renal Insufficiency	1
Liver Diseases	1
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Clinical Trial Locations for Tavapadon

Trials by Country

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Trials by Country for
Location	Trials
United States	76
Australia	12
Poland	10
Ukraine	8
France	7
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Trials by US State

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Trials by US State for
Location	Trials
Texas	5
Florida	5
Washington	4
Virginia	4
Ohio	4
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Clinical Trial Progress for Tavapadon

Clinical Trial Phase

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Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 3	4
Phase 1	5
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Clinical Trial Status

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Clinical Trial Status for
Clinical Trial Phase	Trials
Recruiting	7
Completed	1
Not yet recruiting	1
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Clinical Trial Sponsors for Tavapadon

Sponsor Name

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Sponsor Name for
Sponsor	Trials
Cerevel Therapeutics, LLC	9
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Sponsor Type

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Sponsor Type for
Sponsor	Trials
Industry	9
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