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Last Updated: May 18, 2024

CLINICAL TRIALS PROFILE FOR TAVAPADON


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Clinical Trials for Tavapadon

Trial ID Title Status Sponsor Phase Summary
NCT04201093 ↗ Fixed-Dose Trial in Early Parkinson's Disease (PD) Recruiting Cerevel Therapeutics, LLC Phase 3 The purpose of this study is to evaluate the clinical efficacy, safety and pharmacokinetics (PK) of 2 fixed doses of tavapadon and placebo in participants with early PD.
NCT04223193 ↗ Flexible-Dose Trial in Early Parkinson's Disease (PD) Recruiting Cerevel Therapeutics, LLC Phase 3 The purpose of this study is to assess the efficacy, safety, tolerability and pharmacokinetics (PK) of flexible doses of tavapadon in participants with Parkinson's Disease.
NCT04241393 ↗ An Open-label Trial to Evaluate Mass Balance of Tavapadon at Steady State in Healthy Subjects Completed Cerevel Therapeutics, LLC Phase 1 The purpose of this trial is to determine the absorption, metabolism, and excretion (AME) of [14C] tavapadon.
NCT04542499 ↗ Flexible-Dose, Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations Recruiting Cerevel Therapeutics, LLC Phase 3 The purpose of this study is to assess the effect of tavapadon on the change from baseline in total daily hours of "on" time without troublesome dyskinesia in L-Dopa-treated participants with Parkinson's Disease (PD) who are experiencing motor fluctuations.
NCT04760769 ↗ Open-label Trial in Parkinson's Disease (PD) Recruiting Cerevel Therapeutics, LLC Phase 3 The purpose of this study is to evaluate the safety and efficacy of long-term administration of flexible doses of tavapadon in participants with Parkinson's Disease.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Tavapadon

Condition Name

Condition Name for
Intervention Trials
Parkinson Disease 6
Healthy Subjects 1
Hepatic Impairment 1
Renal Impairment 1
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Condition MeSH

Condition MeSH for
Intervention Trials
Parkinson Disease 6
Liver Diseases 1
Renal Insufficiency 1
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Clinical Trial Locations for Tavapadon

Trials by Country

Trials by Country for
Location Trials
United States 76
Australia 12
Poland 10
Ukraine 8
France 7
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Trials by US State

Trials by US State for
Location Trials
Florida 5
Texas 5
California 4
Washington 4
Virginia 4
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Clinical Trial Progress for Tavapadon

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 4
Phase 1 5
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Recruiting 7
Completed 1
Not yet recruiting 1
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Clinical Trial Sponsors for Tavapadon

Sponsor Name

Sponsor Name for
Sponsor Trials
Cerevel Therapeutics, LLC 9
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Sponsor Type

Sponsor Type for
Sponsor Trials
Industry 9
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