CLINICAL TRIALS PROFILE FOR TALAROZOLE

Clinical Trials for Talarozole

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00716144 ↗	Dose Ranging Study of the Safety and Efficacy of R115966 in Plaque Psoriasis	Completed	GlaxoSmithKline	Phase 2	Eligible subjects will be randomly assigned to one of three dose regimens of oral R115866 or placebo for the treatment of severe plaque psoriasis for 12 twelve weeks. The safety and efficacy of R115866 will be evaluated during the treatment period and the 8-week post treatment follow-up period.
NCT00716144 ↗	Dose Ranging Study of the Safety and Efficacy of R115966 in Plaque Psoriasis	Completed	Stiefel, a GSK Company	Phase 2	Eligible subjects will be randomly assigned to one of three dose regimens of oral R115866 or placebo for the treatment of severe plaque psoriasis for 12 twelve weeks. The safety and efficacy of R115866 will be evaluated during the treatment period and the 8-week post treatment follow-up period.
NCT00719121 ↗	Study on Anti-inflammatory Effects of Topical R115866 Gel	Completed	Stiefel, a GSK Company	Phase 1	The purpose of this exploratory trial is to assess the anti-inflammatory effect(s) of topical R115866 in a model of UVB-induced inflammation and in a model of cutaneous irritation.
NCT00725348 ↗	An Open-Label, Multi-Center Trial in the Treatment of Subjects With Moderate to Severe Plaque Type Psoriasis	Completed	Stiefel, a GSK Company	Phase 2	This is a study of a new oral drug used for the treatment of psoriasis. All subjects will get active medication, there is no placebo arm.
NCT00725439 ↗	An Open Label Trial to Assess the Safety and Efficacy of Oral R115866 in the Treatment Facial Acne	Completed	Stiefel, a GSK Company	Phase 2	This study is looking at a new oral drug to treat acne. All patients in the study will get active drug, there is no placebo arm.

Clinical Trial Conditions for Talarozole

Condition Name

Condition Name for
Intervention	Trials
Psoriasis	2
Acne	1
Cutaneous Inflammation	1

Condition MeSH

Condition MeSH for
Intervention	Trials
Psoriasis	2
Acne Vulgaris	1
Inflammation	1
Dermatitis	1

Clinical Trial Locations for Talarozole

Trials by Country

Trials by Country for
Location	Trials
Netherlands	3
Belgium	2
Ireland	1
United Kingdom	1
Germany	1

Clinical Trial Progress for Talarozole

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 2	3
Phase 1	1

Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase	Trials
Completed	4

Clinical Trial Sponsors for Talarozole

Sponsor Name

Sponsor Name for
Sponsor	Trials
Stiefel, a GSK Company	4
GlaxoSmithKline	1

Sponsor Type

Sponsor Type for
Sponsor	Trials
Industry	5