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Last Updated: December 31, 2025

CLINICAL TRIALS PROFILE FOR SERLOPITANT

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Clinical Trials for Serlopitant

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT01951274 ↗	VPD-737 for Treatment of Chronic Pruritus	Completed	Menlo Therapeutics Inc.	Phase 2	A study of a several doses of a novel treatment for chronic itch compared to placebo for patients whose condition has not responded to other treatments
NCT01951274 ↗	VPD-737 for Treatment of Chronic Pruritus	Completed	Vyne Therapeutics Inc.	Phase 2	A study of a several doses of a novel treatment for chronic itch compared to placebo for patients whose condition has not responded to other treatments
NCT02196324 ↗	A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN)	Completed	Menlo Therapeutics Inc.	Phase 2	The purpose of this study is to demonstrate whether or not VPD-737, an NK1 receptor antagonist is safe and effective for treatment of prurigo nodularis versus placebo.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Serlopitant

Condition Name

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Condition Name
Intervention	Trials
Pruritus	8
Prurigo Nodularis	4
Atopic Dermatitis	2
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Condition MeSH

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Condition MeSH
Intervention	Trials
Pruritus	10
Prurigo	4
Neurodermatitis	3
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Clinical Trial Locations for Serlopitant

Trials by Country

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Trials by Country
Location	Trials
United States	152
Germany	3
Austria	2
Poland	2
United Kingdom	1
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Trials by US State

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Trials by US State
Location	Trials
California	9
Florida	8
Texas	7
North Carolina	7
New York	7
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Clinical Trial Progress for Serlopitant

Clinical Trial Phase

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Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 3	3
Phase 2	9
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Clinical Trial Status

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Clinical Trial Status
Clinical Trial Phase	Trials
Completed	9
Terminated	2
Recruiting	1
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Clinical Trial Sponsors for Serlopitant

Sponsor Name

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Sponsor Name
Sponsor	Trials
Menlo Therapeutics Inc.	11
Vyne Therapeutics Inc.	11
Epidermolysis Bullosa Research Partnership	2
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Sponsor Type

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Sponsor Type
Sponsor	Trials
Industry	22
Other	5
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