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Last Updated: April 20, 2024

CLINICAL TRIALS PROFILE FOR SERLOPITANT


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Clinical Trials for Serlopitant

Trial ID Title Status Sponsor Phase Summary
NCT01951274 ↗ VPD-737 for Treatment of Chronic Pruritus Completed Menlo Therapeutics Inc. Phase 2 A study of a several doses of a novel treatment for chronic itch compared to placebo for patients whose condition has not responded to other treatments
NCT01951274 ↗ VPD-737 for Treatment of Chronic Pruritus Completed Vyne Therapeutics Inc. Phase 2 A study of a several doses of a novel treatment for chronic itch compared to placebo for patients whose condition has not responded to other treatments
NCT02196324 ↗ A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN) Completed Menlo Therapeutics Inc. Phase 2 The purpose of this study is to demonstrate whether or not VPD-737, an NK1 receptor antagonist is safe and effective for treatment of prurigo nodularis versus placebo.
NCT02196324 ↗ A Randomized Placebo-Controlled Study of the Neurokinin-1 (NK1) Receptor Antagonist Serlopitant Prurigo Nodularis (PN) Completed Vyne Therapeutics Inc. Phase 2 The purpose of this study is to demonstrate whether or not VPD-737, an NK1 receptor antagonist is safe and effective for treatment of prurigo nodularis versus placebo.
NCT02654483 ↗ Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients Completed Epidermolysis Bullosa Research Partnership Phase 2 Our goal is to determine whether daily oral administration of VPD-737 (5 mg) is effective and safe in treating moderate to severe pruritus in patients with Epidermolysis Bullosa (EB).
NCT02654483 ↗ Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients Completed Menlo Therapeutics Inc. Phase 2 Our goal is to determine whether daily oral administration of VPD-737 (5 mg) is effective and safe in treating moderate to severe pruritus in patients with Epidermolysis Bullosa (EB).
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Serlopitant

Condition Name

Condition Name for
Intervention Trials
Pruritus 8
Prurigo Nodularis 4
Atopic Dermatitis 2
Epidermolysis Bullosa 2
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Condition MeSH

Condition MeSH for
Intervention Trials
Pruritus 10
Prurigo 4
Neurodermatitis 3
Epidermolysis Bullosa 2
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Clinical Trial Locations for Serlopitant

Trials by Country

Trials by Country for
Location Trials
United States 152
Germany 3
Poland 2
Austria 2
United Kingdom 1
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Trials by US State

Trials by US State for
Location Trials
California 9
Florida 8
Texas 7
New York 7
New Jersey 7
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Clinical Trial Progress for Serlopitant

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 3
Phase 2 9
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Completed 9
Terminated 2
Recruiting 1
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Clinical Trial Sponsors for Serlopitant

Sponsor Name

Sponsor Name for
Sponsor Trials
Menlo Therapeutics Inc. 11
Vyne Therapeutics Inc. 11
Epidermolysis Bullosa Research Partnership 2
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Sponsor Type

Sponsor Type for
Sponsor Trials
Industry 22
Other 5
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