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Last Updated: April 23, 2024

CLINICAL TRIALS PROFILE FOR SEMAPIMOD

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Clinical Trials for Semapimod

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00038766 ↗	CNI-1493 for Treatment of Moderate to Severe Crohn's Disease	Terminated	Ferring Pharmaceuticals	Phase 2	The purpose of this study is to determine whether CNI-1493 is safe and effective in the treatment of moderate to severe Crohn's Disease.
NCT00739986 ↗	Semapimod for Treatment of Moderate to Severe Crohn's Disease 1 or 3 Days' Treatment Versus Placebo	Completed	Ferring Pharmaceuticals	Phase 2	Assessment of the number of days' treatment with semapimod necessary for efficacy, as measured by response rate to CNI-1493 as compared to placebo, in patients with moderate to severe Crohn's disease (CD).
NCT00740103 ↗	Long-term Study of Semapimod (CNI-1493) for Treatment of Crohn's Disease	Completed	Ferring Pharmaceuticals	Phase 2	CNI-1493-CD05 is an open-label extension study of CNI-1493-CD04. In the CD05 study, patients are eligible for up to 5 courses of semapimod 60 mg IV x 3 days every 6 - 8 weeks. Primary objective is assessment of the efficacy of cumulative doses of semapimod measured by decrease in Crohn's Disease Activity Index (CDAI).
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Semapimod

Condition Name

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Condition Name for
Intervention	Trials
Crohn's Disease	4
Crohn Disease	1
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Condition MeSH

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Condition MeSH for
Intervention	Trials
Crohn Disease	5
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Clinical Trial Locations for Semapimod

Trials by Country

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Trials by Country for
Location	Trials
United States	23
Israel	3
Germany	3
Netherlands	3
Belgium	2
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Trials by US State

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Trials by US State for
Location	Trials
New York	4
Illinois	4
Georgia	3
California	3
Tennessee	2
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Clinical Trial Progress for Semapimod

Clinical Trial Phase

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Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 2	4
Phase 1	1
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Clinical Trial Status

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Clinical Trial Status for
Clinical Trial Phase	Trials
Completed	4
Terminated	1
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Clinical Trial Sponsors for Semapimod

Sponsor Name

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Sponsor Name for
Sponsor	Trials
Ferring Pharmaceuticals	5
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Sponsor Type

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Sponsor Type for
Sponsor	Trials
Industry	5
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