Last Updated: October 1, 2026

CLINICAL TRIALS PROFILE FOR RADIUM-223

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Clinical Trials for Radium-223

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00337155 ↗	BAY88-8223, Dose Finding Study in Patients With HRPC	Completed	Bayer	Phase 2	The purpose of this study is to evaluate the effectiveness of the investigational radioisotope Radium-223, Alpharadin, in treatment of men with prostate cancer and bone metastases that no longer respond to hormonal treatment.
NCT00459654 ↗	A Placebo-controlled Phase II Study of Bone-targeted Radium-223 in Symptomatic Hormone-refractory Prostate Cancer	Completed	Bayer	Phase 2	The purpose of this study is to evaluate the effectiveness of the investigational radioisotope Radium-223 in treatment of men with prostate cancer and bone metastases that no longer respond to hormonal treatment.
NCT00667199 ↗	BAY88-8223, Does Response Study in HRPC Patients	Completed	Bayer	Phase 2	The purpose of this study is to evaluate the efficacy and safety of the investigational radioisotope Radium-223, Xofigo (Alpharadin), in treatment of men with prostate cancer and bone metastases that no longer respond to hormonal treatment.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Radium-223

Condition Name

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Condition Name
Intervention	Trials
Prostate Cancer	21
Prostatic Neoplasms	12
Bone Metastases	8
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Condition MeSH

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Condition MeSH
Intervention	Trials
Prostatic Neoplasms	67
Neoplasm Metastasis	18
Carcinoma	9
[disabled in preview]	1
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Clinical Trial Locations for Radium-223

Trials by Country

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Trials by Country
Location	Trials
United States	354
Italy	83
United Kingdom	64
Spain	61
Germany	56
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Trials by US State

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Trials by US State
Location	Trials
California	23
New York	18
Maryland	17
Pennsylvania	16
North Carolina	16
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Clinical Trial Progress for Radium-223

Clinical Trial Phase

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Clinical Trial Phase
Clinical Trial Phase	Trials
PHASE2	2
Phase 4	3
Phase 3	11
[disabled in preview]	0
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Clinical Trial Status

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Clinical Trial Status
Clinical Trial Phase	Trials
Completed	29
Recruiting	21
Active, not recruiting	15
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Clinical Trial Sponsors for Radium-223

Sponsor Name

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Sponsor Name
Sponsor	Trials
Bayer	45
National Cancer Institute (NCI)	6
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	4
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Sponsor Type

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Sponsor Type
Sponsor	Trials
Industry	62
Other	59
NIH	6
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