Study of MLN4924 Plus Azacitidine in Treatment-naive Participants With Acute Myelogenous Leukemia (AML) Who Are 60 Years or Older
Completed
Millennium Pharmaceuticals, Inc.
Phase 1
The purpose of this study is to establish the maximum tolerated dose (MTD), and to assess the
safety and tolerability of MLN4924 (pevonedistat) in combination with azacitidine in
treatment naive participants with AML who were 60 years of age or older.
Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid Tumors
Completed
Millennium Pharmaceuticals, Inc.
Phase 1
The purpose of this study is to establish the maximum tolerated dose (MTD) and assess the
safety and tolerability of MLN4924 (pevonedistat) in combination with docetaxel, paclitaxel
and carboplatin, and gemcitabine in participants with solid tumors.
An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML)
Completed
Millennium Pharmaceuticals, Inc.
Phase 2
The purpose of this study is to evaluate the efficacy and safety of pevonedistat plus
azacitidine versus single-agent azacitidine in participants with HR-MDS or CMML, or low-blast
AML.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
