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Last Updated: April 26, 2024

CLINICAL TRIALS PROFILE FOR PF-04965842


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Clinical Trials for PF-04965842

Trial ID Title Status Sponsor Phase Summary
NCT01835197 ↗ First-in-Human Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of Janus Kinase-1 Inhibitor PF-04965842 in Healthy Western and Japanese Subjects Completed Pfizer Phase 1 This single- and multiple-ascending dose study is the first evaluation of PF-04965842, a Janus kinase1 (JAK1) inhibitor, in humans. The goal is to assess the safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Western and Japanese subjects.
NCT02163161 ↗ AStudy to Evaluate the Bioavailability of PF 04965842 in Healthy Subjects Completed Pfizer Phase 1 Phase 1, open label, single dose, 3 way crossover study to evaluate the bioavailability of a solid dose formulation of PF 04965842 relative to a suspension formulation under fasting conditions and the effect of food on the bioavailability of the solid dosage formulation of PF 04965842 in healthy subjects.
NCT02201524 ↗ Study to Evaluate PF-04965842 in Patients With Moderate to Severe Psoriasis Terminated Pfizer Phase 2 Study B7451005 is a Phase 2 study which will assess the efficacy and safety of PF-04965842 in patients with moderate to severe psoriasis. The study will include three PF-04965842 groups (200 mg daily, 400 mg daily and 200 mg twice daily) and a placebo group. The treatment period will be 4 weeks in duration and will be followed up by a 4 week follow up period.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for PF-04965842

Condition Name

Condition Name for
Intervention Trials
Healthy 9
Dermatitis, Atopic 7
Atopic Dermatitis 3
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Condition MeSH

Condition MeSH for
Intervention Trials
Dermatitis, Atopic 10
Dermatitis 10
Eczema 8
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Clinical Trial Locations for PF-04965842

Trials by Country

Trials by Country for
Location Trials
United States 176
China 38
Canada 38
United Kingdom 30
Australia 27
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Trials by US State

Trials by US State for
Location Trials
Florida 11
Indiana 9
California 9
Texas 9
Virginia 8
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Clinical Trial Progress for PF-04965842

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 6
Phase 2 3
Phase 1 16
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Completed 22
Active, not recruiting 1
Enrolling by invitation 1
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Clinical Trial Sponsors for PF-04965842

Sponsor Name

Sponsor Name for
Sponsor Trials
Pfizer 25
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Sponsor Type

Sponsor Type for
Sponsor Trials
Industry 25
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