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Last Updated: November 22, 2019

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CLINICAL TRIALS PROFILE FOR LINIFANIB

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Clinical Trials for Linifanib

Trial ID Title Status Sponsor Phase Summary
NCT00733187 Pharmacokinetic Study To Evaluate Effect of Food and Diurnal Variation on ABT-869 Completed Genentech, Inc. Phase 1 To estimate the effect of food on the oral bioavailability and effect of diurnal variation on the pharmacokinetics of ABT-869.
NCT00733187 Pharmacokinetic Study To Evaluate Effect of Food and Diurnal Variation on ABT-869 Completed AbbVie (prior sponsor, Abbott) Phase 1 To estimate the effect of food on the oral bioavailability and effect of diurnal variation on the pharmacokinetics of ABT-869.
NCT01009593 Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC) Terminated Abbott Phase 3 The primary objective of this study is to assess the overall survival (OS) of oral linifanib given as monotherapy once daily (QD) compared to sorafenib given twice daily (BID) per standard of care in subjects with advanced or metastatic HCC.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Linifanib

Condition Name

Condition Name for
Intervention Trials
Advanced Solid Tumors 5
Hepatocellular Carcinoma Non-resectable 1
Neoplasms by Site 1
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Condition MeSH

Condition MeSH for
Intervention Trials
Liver Diseases 1
Carcinoma, Non-Small-Cell Lung 1
Adenocarcinoma 1
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Clinical Trial Locations for Linifanib

Trials by Country

Trials by Country for
Location Trials
United States 28
Japan 2
Egypt 1
Puerto Rico 1
China 1
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Trials by US State

Trials by US State for
Location Trials
Michigan 4
New Hampshire 3
Texas 2
Maryland 2
Wisconsin 2
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Clinical Trial Progress for Linifanib

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 1
Phase 2 1
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Completed 6
Terminated 4
Not yet recruiting 1
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Clinical Trial Sponsors for Linifanib

Sponsor Name

Sponsor Name for
Sponsor Trials
Abbott 8
Genentech, Inc. 1
BioGene Pharmaceutical Ltd. 1
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Sponsor Type

Sponsor Type for
Sponsor Trials
Industry 11
Other 1
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