Last Updated: June 24, 2026

CLINICAL TRIALS PROFILE FOR LY3410738


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Clinical Trials for LY3410738

Trial ID Title Status Sponsor Phase Summary
NCT04521686 ↗ Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations Recruiting Eli Lilly and Company Phase 1 This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitrate dehydrogenase 1 (IDH1) arginine 130 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, and glioma or isocitrate dehydrogenase 2 (IDH2) arginine 140 (R140) or arginine 172 (R172) mutant cholangiocarcinoma.
NCT04521686 ↗ Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations Recruiting Loxo Oncology, Inc. Phase 1 This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitrate dehydrogenase 1 (IDH1) arginine 130 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, and glioma or isocitrate dehydrogenase 2 (IDH2) arginine 140 (R140) or arginine 172 (R172) mutant cholangiocarcinoma.
NCT04603001 ↗ Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations Recruiting Eli Lilly and Company Phase 1 This is an open-label, multi-center Phase 1 study of LY3410738, an oral, covalent IDH inhibitor, in patients with IDH1 and/or IDH2-mutant advanced hematologic malignancies who have received standard therapy
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for LY3410738

Condition Name

Condition Name
Intervention Trials
Healthy 3
Myeloproliferative Neoplasms (MPNs) 1
Acute Myeloid Leukemia (AML) 1
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Condition MeSH

Condition MeSH
Intervention Trials
Glioma 1
Myelodysplastic Syndromes 1
Chondrosarcoma 1
[disabled in preview] 1
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Clinical Trial Locations for LY3410738

Trials by Country

Trials by Country
Location Trials
United States 22
Japan 5
Korea, Republic of 4
Australia 3
France 2
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Trials by US State

Trials by US State
Location Trials
Florida 4
Texas 2
Tennessee 2
New York 2
Massachusetts 2
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Clinical Trial Progress for LY3410738

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase Trials
Phase 1 5
[disabled in preview] 0
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Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase Trials
Recruiting 3
Completed 2
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Clinical Trial Sponsors for LY3410738

Sponsor Name

Sponsor Name
Sponsor Trials
Eli Lilly and Company 7
Loxo Oncology, Inc. 7
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Sponsor Type

Sponsor Type
Sponsor Trials
Industry 14
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