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Last Updated: May 16, 2024

CLINICAL TRIALS PROFILE FOR JNJ-70033093

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Clinical Trials for JNJ-70033093

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT03891524 ↗	A Study of JNJ-70033093 (BMS-986177) Versus Subcutaneous Enoxaparin in Participants Undergoing Elective Total Knee Replacement Surgery	Completed	Bristol-Myers Squibb	Phase 2	The purpose of this study is to determine the efficacy of JNJ-70033093 in preventing total venous thromboembolism (VTE) events (proximal and/or distal deep vein thrombosis [DVT] [asymptomatic confirmed by venography assessment or objectively confirmed symptomatic], nonfatal pulmonary embolism [PE], or any death) during the treatment period.
NCT03891524 ↗	A Study of JNJ-70033093 (BMS-986177) Versus Subcutaneous Enoxaparin in Participants Undergoing Elective Total Knee Replacement Surgery	Completed	Janssen Research & Development, LLC	Phase 2	The purpose of this study is to determine the efficacy of JNJ-70033093 in preventing total venous thromboembolism (VTE) events (proximal and/or distal deep vein thrombosis [DVT] [asymptomatic confirmed by venography assessment or objectively confirmed symptomatic], nonfatal pulmonary embolism [PE], or any death) during the treatment period.
NCT04206488 ↗	A Study of JNJ-70033093 and Digoxin in Healthy Participants	Recruiting	Bristol-Myers Squibb	Phase 1	The purpose of this study is to evaluate the potential pharmacokinetic (PK) interaction between JNJ-70033093 and digoxin in healthy participants after single dose administration and at steady state.
NCT04206488 ↗	A Study of JNJ-70033093 and Digoxin in Healthy Participants	Recruiting	Janssen Research & Development, LLC	Phase 1	The purpose of this study is to evaluate the potential pharmacokinetic (PK) interaction between JNJ-70033093 and digoxin in healthy participants after single dose administration and at steady state.
NCT04223349 ↗	A Study of JNJ-70033093 (BMS-986177) in Healthy Adult Participants	Completed	Janssen Research & Development, LLC	Phase 1	The purpose of this study is to characterize the pharmacokinetic (PK) of multiple twice-daily doses of JNJ-70033093 in healthy participants and to assess the effects of dosing time and food on the PK of single-dose of JNJ-70033093 in healthy participants.
NCT04388501 ↗	A Study Evaluating Drug Drug Interaction Between Milvexian and Atorvastatin in Healthy Participants	Recruiting	Janssen Pharmaceutica N.V., Belgium	Phase 1	The purpose of this study is to evaluate the potential pharmacokinetics (PK) interaction between milvexian and atorvastatin (and its metabolites) in healthy participants at steady state.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for JNJ-70033093

Condition Name

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Condition Name for
Intervention	Trials
Healthy	7
Acute Coronary Syndrome	1
Arthroplasty, Replacement, Knee	1
Healthy Female	1
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Condition MeSH

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Condition MeSH for
Intervention	Trials
Ischemic Stroke	1
Ischemic Attack, Transient	1
Ischemia	1
Cerebral Infarction	1
[disabled in preview]	0
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Clinical Trial Locations for JNJ-70033093

Trials by Country

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Trials by Country for
Location	Trials
United States	67
Canada	10
Belgium	7
China	3
Hungary	3
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Trials by US State

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Trials by US State for
Location	Trials
Texas	3
Colorado	3
California	3
Arizona	3
Florida	3
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Clinical Trial Progress for JNJ-70033093

Clinical Trial Phase

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Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 3	2
Phase 2	1
Phase 1	9
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Clinical Trial Status

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Clinical Trial Status for
Clinical Trial Phase	Trials
Recruiting	5
Completed	3
Not yet recruiting	3
[disabled in preview]	1
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Clinical Trial Sponsors for JNJ-70033093

Sponsor Name

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Sponsor Name for
Sponsor	Trials
Janssen Research & Development, LLC	9
Bristol-Myers Squibb	4
Janssen Pharmaceutica N.V., Belgium	2
[disabled in preview]	2
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Sponsor Type

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Sponsor Type for
Sponsor	Trials
Industry	15
Other	2
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