Study Of The Effects Of SB 480848 (Darapladib) On The Electrical Conduction Of The Heart
This is a study to assess the effects of darapladib on the cardiac conduction of the heart
as compared to placebo and moxifloxacin. This a four period crossover design with each
period lasting about 10 days. There will be a 7 to 10 day wash out in between each period.
A Study With Darapladib to Collect Tolerability Information
Subjects will receive their first dose of darapladib in the clinical research unit (CRU),
and the remaining 9 days of dosing will occur at home. Subjects will record any adverse
events throughout the dosing period in a paper diary. Subjects will return to the CRU 10-14
days after the last dose of darapladib for a follow-up visit. The total study duration for
each subject including the screening, treatment and follow-up periods will be approximately
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