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Last Updated: April 26, 2024

CLINICAL TRIALS PROFILE FOR CAMPTOTHECIN

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Clinical Trials for Camptothecin

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00001427 ↗	A Phase II Trial of 72-Hour Continuous IV Infusion of 9-Aminocamptothecin With G-CSF Support in Patients With Advanced Ovarian Cancer Previously Treated With Paclitaxel and Cisplatin	Completed	National Cancer Institute (NCI)	Phase 2	The objectives of this study are to determine the response rate to 9-AC in patients with advanced ovarian cancer who have recurrent disease after paclitaxel- and cisplatin-based chemotherapy regimens.
NCT00001495 ↗	A Phase I Study of Irinotecan (CPT-11) Administered as a Prolonged Infusion in Adult Patients With Solid Tumors	Completed	National Cancer Institute (NCI)	Phase 1	This study examines a 96 hour infusion schedule of irinotecan alternating with 72 hour drug-free intervals in patients with solid tumors in order to determine the maximum tolerated dose of this regimen.
NCT00002635 ↗	Aminocamptothecin in Treating Patients With T-cell Lymphoma	Completed	National Cancer Institute (NCI)	Phase 2	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of aminocamptothecin in treating patients with advanced cutaneous T-cell lymphoma.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Camptothecin

Condition Name

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Condition Name for
Intervention	Trials
Colorectal Cancer	9
Cancer	7
Lung Cancer	7
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Condition MeSH

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Condition MeSH for
Intervention	Trials
Neoplasms	23
Adenocarcinoma	20
Lung Neoplasms	19
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Clinical Trial Locations for Camptothecin

Trials by Country

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Trials by Country for
Location	Trials
United States	943
Canada	61
Australia	26
China	11
Korea, Republic of	10
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Trials by US State

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Trials by US State for
Location	Trials
California	46
New York	36
Texas	36
Pennsylvania	34
Maryland	31
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Clinical Trial Progress for Camptothecin

Clinical Trial Phase

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Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 3	11
Phase 2	75
Phase 1/Phase 2	17
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Clinical Trial Status

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Clinical Trial Status for
Clinical Trial Phase	Trials
Completed	77
Recruiting	18
Active, not recruiting	18
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Clinical Trial Sponsors for Camptothecin

Sponsor Name

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Sponsor Name for
Sponsor	Trials
National Cancer Institute (NCI)	74
Astex Pharmaceuticals	10
Astex Pharmaceuticals, Inc.	10
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Sponsor Type

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Sponsor Type for
Sponsor	Trials
Other	124
NIH	74
Industry	71
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