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Generated: December 12, 2018

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CLINICAL TRIALS PROFILE FOR CAMPTOTHECIN

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Clinical Trials for Camptothecin

Trial ID Title Status Sponsor Phase Summary
NCT00001427 A Phase II Trial of 72-Hour Continuous IV Infusion of 9-Aminocamptothecin With G-CSF Support in Patients With Advanced Ovarian Cancer Previously Treated With Paclitaxel and Cisplatin Completed National Cancer Institute (NCI) Phase 2 The objectives of this study are to determine the response rate to 9-AC in patients with advanced ovarian cancer who have recurrent disease after paclitaxel- and cisplatin-based chemotherapy regimens.
NCT00001495 A Phase I Study of Irinotecan (CPT-11) Administered as a Prolonged Infusion in Adult Patients With Solid Tumors Completed National Cancer Institute (NCI) Phase 1 This study examines a 96 hour infusion schedule of irinotecan alternating with 72 hour drug-free intervals in patients with solid tumors in order to determine the maximum tolerated dose of this regimen.
NCT00002635 Aminocamptothecin in Treating Patients With T-cell Lymphoma Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of aminocamptothecin in treating patients with advanced cutaneous T-cell lymphoma.
NCT00002635 Aminocamptothecin in Treating Patients With T-cell Lymphoma Completed Yale University Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of aminocamptothecin in treating patients with advanced cutaneous T-cell lymphoma.
NCT00002671 Aminocamptothecin in Treating Patients With Recurrent or Unresectable Epithelial Ovarian Cancer Completed Eastern Cooperative Oncology Group Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of aminocamptothecin in treating patients with recurrent or unresectable epithelial ovarian cancer that has been previously treated with platinum-based chemotherapy.
Trial ID Title Status Sponsor Phase Summary

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Clinical Trial Conditions for Camptothecin

Condition Name

Condition Name for
Intervention Trials
Cancer 6
Solid Tumors 6
Ovarian Cancer 5
Lymphoma 5
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Condition MeSH

Condition MeSH for
Intervention Trials
Lung Neoplasms 11
Small Cell Lung Carcinoma 9
Lymphoma 9
Colorectal Neoplasms 6
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Clinical Trial Locations for Camptothecin

Trials by Country

Trials by Country for
Location Trials
United States 179
France 4
Spain 4
Italy 4
Canada 3
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Trials by US State

Trials by US State for
Location Trials
California 17
New York 13
Maryland 13
Illinois 9
Texas 9
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Clinical Trial Progress for Camptothecin

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 6
Phase 2 43
Phase 1/Phase 2 9
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Completed 54
Unknown status 11
Recruiting 10
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Clinical Trial Sponsors for Camptothecin

Sponsor Name

Sponsor Name for
Sponsor Trials
National Cancer Institute (NCI) 28
Astex Pharmaceuticals 9
University of New Mexico 5
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Sponsor Type

Sponsor Type for
Sponsor Trials
Other 65
Industry 39
NIH 28
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