CLINICAL TRIALS PROFILE FOR BRILACIDIN

Clinical Trials for Brilacidin

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT02052388 ↗	Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infections	Completed	Cellceutix Corporation	Phase 2	The purpose of this study is to determine the safety and efficacy of three different dosing regimens of brilacidin compared to daptomycin for the treatment of serious skin infections. This study will aid in selecting the appropriate dose of brilacidin for later stage studies.
NCT02324335 ↗	Study of the Effects of Brilacidin Oral Rinse on Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer	Completed	Cellceutix Corporation	Phase 2	Oral Mucositis (OM) is a painful and debilitating side effect of many of the drug/radiation regimens used to treat cancer. This study examines the investigational drug brilacidin and its possible application in prevention of oral mucositis in patients undergoing chemoradiation for treatment of head and neck cancer.
NCT02324335 ↗	Study of the Effects of Brilacidin Oral Rinse on Radiation-induced Oral Mucositis in Patients With Head and Neck Cancer	Completed	Innovation Pharmaceuticals, Inc.	Phase 2	Oral Mucositis (OM) is a painful and debilitating side effect of many of the drug/radiation regimens used to treat cancer. This study examines the investigational drug brilacidin and its possible application in prevention of oral mucositis in patients undergoing chemoradiation for treatment of head and neck cancer.
NCT04240223 ↗	A Study to Investigate the Use of Delayed Release Tablets for Colonic Delivery of Brilacidin in Healthy Volunteers	Completed	Innovation Pharmaceuticals, Inc.	Phase 1	This is a single-centre, blinded, randomized, placebo controlled, dose escalation study. Up to 9 healthy male volunteers will participate in the study. This study is designed to investigate the use of delayed release tablets for colonic delivery of Brilacidin.
NCT04784897 ↗	A Study to Evaluate the Efficacy and Safety of Brilacidin in Hospitalized Participants With COVID-19	Completed	Innovation Pharmaceuticals, Inc.	Phase 2	The study will assess the efficacy and safety of Brilacidin for the treatment of COVID-19 in hospitalized participants

Clinical Trial Conditions for Brilacidin

Condition Name

Condition Name for
Intervention	Trials
Healthy Volunteers	1
Mouth Diseases	1
Mucositis	1
Skin Infection	1

Condition MeSH

Condition MeSH for
Intervention	Trials
Infections	1
COVID-19	1
Infection	1
Stomatitis	1

Clinical Trial Locations for Brilacidin

Trials by Country

Trials by Country for
Location	Trials
United States	17
Russian Federation	1
United Kingdom	1

Trials by US State

Trials by US State for
Location	Trials
Ohio	2
Louisiana	2
Illinois	1
Wisconsin	1
South Carolina	1

Clinical Trial Progress for Brilacidin

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 2	3
Phase 1	1

Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase	Trials
Completed	4

Clinical Trial Sponsors for Brilacidin

Sponsor Name

Sponsor Name for
Sponsor	Trials
Innovation Pharmaceuticals, Inc.	3
Cellceutix Corporation	2

Sponsor Type

Sponsor Type for
Sponsor	Trials
Industry	5