Belotecan (CKD-602) in Recurrent or Progressive Carcinoma of Uterine Cervix
Completed
Sokbom Kang
Phase 2
-list item one, The purpose of this study is to evaluate the overall response rate of
belotecan (CKD-602) in recurrent or progressive carcinoma of uterine cervix
Belotecan and Cisplatin in Treating Patients With Previously Untreated, Extensive-Stage Small Cell Lung Cancer
Completed
Yonsei University
Phase 2
RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the
growth of tumor cells, either by killing the cells or by stopping them from dividing.
Belotecan may stop the growth of tumor cells by blocking some of the enzymes needed for cell
growth. Giving belotecan together with cisplatin may kill more tumor cells.
PURPOSE: This phase II trial is studying how well belotecan works when given together with
cisplatin in treating patients with previously untreated extensive stage small cell lung
cancer.
Trial of Belotecan/Cisplatin in Chemotherapy Naive Small Cell Lung Cancer Patient
Completed
Chong Kun Dang Pharmaceutical
Phase 3
Belotecan (Camtobell, CKD-602, Chong Kun Dang Pharm., Korea) is a new camptothecin
derivative, that exhibits anticancer effects by inhibiting topoisomerase I. The investigators
will have a randomized prospective multicenter trial of Belotecan/Cisplatin versus
Etoposide/Cisplatin in patients with previously untreated, extensive-stage small cell lung
cancer.
Primary endpoints
- to assess Response Rate
Secondary endpoints
- to assess Overall response duration, Time to progression, Overall survival
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