Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma
Completed
National Cancer Institute (NCI)
Phase 1
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing
so they stop growing or die.
PURPOSE: Phase I trial to study the effectiveness of atrasentan in treating patients who have
progressive or recurrent malignant glioma.
Safety and Efficacy of Atrasentan in Men With Hormone Naive Prostate Cancer Exhibiting Early Signs of Biochemical Failure
Completed
Abbott
Phase 2
The purpose of this phase II, randomized, double-blind placebo controlled, multi-center study
is to evaluate the safety and efficacy of 10 mg atrasentan in hormone naive subjects as
measured by rate of rise in the PSA (primary objective).
Atrasentan in Treating Patients With Locally Recurrent or Metastatic Kidney Cancer
Completed
National Cancer Institute (NCI)
Phase 2
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die.
PURPOSE: This phase II trial is studying how well atrasentan works in treating patients with
locally recurrent or metastatic kidney cancer.
Atrasentan in Treating Patients With Locally Recurrent or Metastatic Kidney Cancer
Completed
Eastern Cooperative Oncology Group
Phase 2
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die.
PURPOSE: This phase II trial is studying how well atrasentan works in treating patients with
locally recurrent or metastatic kidney cancer.
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