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Last Updated: March 18, 2024

CLINICAL TRIALS PROFILE FOR APAZIQUONE


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Clinical Trials for Apaziquone

Trial ID Title Status Sponsor Phase Summary
NCT00141531 ↗ Phase II Trial of EOquin in High-risk Superficial Bladder Cancer Completed Spectrum Pharmaceuticals, Inc Phase 2 A non-randomized, open-label phase II study to explore the feasibility, time to recurrence, duration of response and safety of the adjuvant intravesical instillation of EOquin (apaziquone) in patients with high-risk superficial bladder tumors, and the response and duration of response in patients with carcinoma in situ of the bladder.
NCT00461591 ↗ Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611) Completed Spectrum Pharmaceuticals, Inc Phase 3 The purpose of this study was to evaluate the 2-Year Recurrence Rate of bladder cancer in randomized patients with tumor histology Ta, G1-G2 who received TransUrethral Resection of Bladder Tumor (TURBT) plus apaziquone versus those who received TURBT plus placebo.
NCT00598806 ↗ Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-612) Completed Spectrum Pharmaceuticals, Inc Phase 3 The purpose of this study was to evaluate the 2-Year Recurrence Rate of bladder cancer in randomized patients with tumor histology Ta, G1-G2 who received TransUrethral Resection of Bladder Tumor (TURBT) plus apaziquone versus those who received TURBT plus placebo.
NCT01373398 ↗ Safety and Pharmacokinetic Study of EO9(Intravesical Instillation) Completed Handok Inc. Phase 1 The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of intravesical instillation of EO9 in patients with non-muscle invasive bladder cancer (NMIBC).
NCT01373398 ↗ Safety and Pharmacokinetic Study of EO9(Intravesical Instillation) Completed Handok Pharmaceuticals Co., Ltd. Phase 1 The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of intravesical instillation of EO9 in patients with non-muscle invasive bladder cancer (NMIBC).
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Apaziquone

Condition Name

Condition Name for
Intervention Trials
Bladder Cancer 8
Bladder Neoplasms 1
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Condition MeSH

Condition MeSH for
Intervention Trials
Urinary Bladder Neoplasms 9
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Clinical Trial Locations for Apaziquone

Trials by Country

Trials by Country for
Location Trials
United States 69
Canada 11
Japan 7
Korea, Republic of 2
Poland 2
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Trials by US State

Trials by US State for
Location Trials
California 4
New Jersey 4
New York 4
Texas 3
Michigan 3
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Clinical Trial Progress for Apaziquone

Clinical Trial Phase

Clinical Trial Phase for
Clinical Trial Phase Trials
Phase 3 6
Phase 2/Phase 3 1
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for
Clinical Trial Phase Trials
Terminated 5
Completed 4
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Clinical Trial Sponsors for Apaziquone

Sponsor Name

Sponsor Name for
Sponsor Trials
Spectrum Pharmaceuticals, Inc 7
Handok Inc. 2
Handok Pharmaceuticals Co., Ltd. 2
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Sponsor Type

Sponsor Type for
Sponsor Trials
Industry 15
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