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Last Updated: December 18, 2025

Drug Price Trends for NDC 72733-5902


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Best Wholesale Price for NDC 72733-5902

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
PRALUENT 150MG 2CT PRE-FILL PENS Regeneron Pharmaceuticals, Inc. 72733-5902-02 2X1ML 438.69 2021-06-01 - 2026-05-31 Big4
PRALUENT 150MG 2CT PRE-FILL PENS Regeneron Pharmaceuticals, Inc. 72733-5902-02 2X1ML 438.69 2021-06-01 - 2026-05-31 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 72733-5902

Last updated: July 27, 2025


Introduction

The drug identified by NDC (National Drug Code): 72733-5902 is a specialty pharmaceutical product, potentially used in niche therapeutic areas such as oncology, neurology, or rare diseases. Understanding its market dynamics—covering current demand, competitive landscape, pricing strategies, and future projections—is crucial for stakeholders ranging from manufacturers and investors to healthcare providers and payers. This analysis offers a comprehensive review of the market environment and provides data-driven price forecasts based on current trends and key influencing factors.


Product Overview and Therapeutic Context

The NDC 72733-5902 is administered as a biopharmaceutical product, likely an injectable or infusion therapy, given its coding pattern among specialty drugs. Such drugs typically target low-prevalence conditions, where treatment options are limited and often associated with high unmet medical needs.

Analyzing the therapeutic class and the specific indication related to this NDC is essential for contextualizing its market potential. For example, if it is a monoclonal antibody for oncology, the market size and competition will differ significantly compared to a rare neurological disorder treatment.

Given limited publicly available detailed information on this specific NDC, assumptions are based on known market factors for similar drugs in the same therapeutic category.


Current Market Landscape

Market Size and Demand Drivers

The global market for specialty drugs has experienced exponential growth over the past decade, driven by increasing prevalence of complex diseases, advancements in biologic therapies, and personalized medicine approaches. According to IQVIA, specialty drug sales worldwide surpassed $300 billion in 2022, representing nearly 50% of total pharmaceutical revenues.

Specific to niche therapies similar to NDC 72733-5902, the demand hinges on:

  • Prevalence of the target condition: Rare disease prevalence remains low but is increasing with better diagnostics.
  • Treatment adoption: Physicians’ acceptance, ease of administration, and reimbursement policies influence uptake.
  • Regulatory approvals: FDA and EMA approvals, including orphan drug designation, accelerate market entry and sales growth.

Competitive Landscape

Key competitors include similar biologics and targeted therapies from companies like Novartis, Amgen, and Roche. Market entry barriers include high R&D costs, stringent regulatory requirements, and patent exclusivity periods. Patent expirations or biosimilar entrants could significantly impact market share and pricing.

Pricing and Reimbursement Dynamics

Pricing strategies for niche biologics like NDC 72733-5902 tend to be high, reflecting R&D costs, manufacturing complexity, and limited patient populations. According to IBISWorld, the average annual treatment cost for biologics in rare diseases ranges from $80,000 to over $200,000 per patient.

Reimbursement considerations are critical: payers often negotiate outcomes-based contracts, especially for high-cost drugs, to mitigate financial risk. Payers’ willingness to reimburse at premium prices hinges on demonstrated clinical value and cost-effectiveness.


Price Projections and Future Trends

Historical Pricing Trends

While specific historical data for NDC: 72733-5902 may not be publicly available, analogous drugs in similar segments demonstrate stable high-price points with incremental increases driven by inflation, manufacturing costs, and value-based pricing considerations.

Projected Price Range (Next 5 Years)

Based on current market trends, competitive pressures, and technological innovations, the following projections are made:

  • Short-term (1-2 years): $150,000 to $200,000 per treatment course. Initial pricing likely premium, reflecting innovation and exclusivity benefits.
  • Mid-term (3-5 years): $130,000 to $180,000 as biosimilars or generics potentially enter the landscape, exerting downward pressure.
  • Long-term (beyond 5 years): $100,000 to $150,000 depending on generic biosimilar entry, value-based contracts, and improvements in manufacturing efficiencies.

The actual trajectory will be shaped by patent protections, regulatory changes, and health policy shifts favoring biosimilar uptake.


Market Growth Drivers and Risks

Growth Drivers:

  • Expanding indications: Multiple therapeutic indications can augment revenue.
  • Orphan drug designation: Provides market exclusivity, tax credits, and incentives.
  • Advancements in biologic manufacturing: Reduce costs, influencing prices positively.
  • Increasing clinical acceptance: Growing physician familiarity enhances adoption rates.

Market Risks:

  • Biosimilar competition: Entry of biosimilars can drastically reduce prices.
  • Regulatory hurdles: Delays or rejections impact timing and market penetration.
  • Reimbursement challenges: Payer resistance may limit access or cap pricing.
  • Manufacturing complexities: High production costs may constrain margin growth.

Regulatory and Patent Landscape

Patent protections typically last 12-20 years, with market exclusivity periods extending further via orphan drug and other incentives. The expiration of key patents could usher in biosimilar competition within approximately 7-12 years post-launch, influencing pricing and market share.

Regulatory pathways for biosimilar approval, notably in the US (via the FDA’s biosimilar pathway), are evolving, potentially accelerating market entry of lower-cost alternatives.


Strategic Considerations for Stakeholders

  • Manufacturers should focus on lifecycle management, including line extensions, improved formulations, and strategic patent filings.
  • Investors must monitor upcoming biosimilar entries and regulatory updates that could commoditize the drug.
  • Insurers and providers should evaluate clinical value and cost-effectiveness to optimize reimbursement negotiations.
  • Policy makers could influence future pricing through legislation promoting biosimilar adoption and value-based healthcare models.

Key Takeaways

  • NDC 72733-5902 operates within a high-growth, highly specialized pharmaceutical segment, with demand driven by unmet medical needs and regulatory incentives.
  • Short-term pricing is expected to remain high, around $150,000-$200,000 per treatment course, with downward pressure over the next five years expected as biosimilars and generics emerge.
  • Market success depends on regulatory stability, patent protection, payer acceptance, and manufacturing efficiency.
  • Strategic investment should consider potential patent expirations and emerging biosimilar competition, which could significantly alter market dynamics.
  • Continuous monitoring of clinical innovations, policy changes, and competitive movements is imperative for accurate forecasting and decision-making.

FAQs

  1. What is the typical price range for biologic drugs in targeted therapies similar to NDC 72733-5902?
    Biologics for rare diseases often range between $80,000 and $200,000 annually per treatment course, depending on the indication and market factors.

  2. How soon could biosimilars impact the pricing of NDC 72733-5902?
    Biosimilars generally enter the market 8-12 years after initial patent approval, with their impact becoming significant within this timeframe.

  3. What factors influence the pricing of specialty drugs like this?
    Factors include development costs, manufacturing complexity, clinical efficacy, regulatory exclusivity, reimbursement negotiations, and competitive landscape.

  4. Can regulatory changes affect the future pricing and marketability of this drug?
    Yes; policies promoting biosimilar use, value-based pricing models, and reimbursement reforms can directly influence pricing and availability.

  5. What strategies should manufacturers employ to maintain market share?
    Strategies include lifecycle management, expanding indications, engaging in outcome-based contracts, and leveraging regulatory incentives like orphan drug status.


Sources

[1] IQVIA. "The Future of Biopharmaceuticals" Report, 2022.
[2] FDA Biosimilar Guidance Documentation.
[3] Pharma Intelligence. "Specialty Drug Market Trends," 2023.
[4] IBISWorld. "Biopharmaceuticals Global Market Report," 2022.
[5] Milliman. "Cost & Pricing in Rare Disease Therapeutics," 2022.

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