Last updated: March 2, 2026
What Is NDC 71093-0138?
NDC 71093-0138 is the National Drug Code identifier for a specific drug product. Based on available data, this code corresponds to Bupropion Hydrochloride Extended-Release (SR) 100 mg, manufactured by a generic producer. This formulation is used primarily for depression and smoking cessation.
Market Overview
Market Size and Demand
The global antidepressant market was valued at approximately USD 16 billion in 2022. Bupropion accounts for about 8% of this market, with annual sales estimated near USD 1.3 billion.
In the United States, prescriptions for bupropion extended-release formulations accounted for roughly 15 million prescriptions in 2022, with a compound annual growth rate (CAGR) of 3% over the past five years.
Competition Landscape
The NDC code indicates a generic product. Major competitors include:
- Brand: Wellbutrin SR (GlaxoSmithKline, now involved in generic licensing)
- Generics: Multiple manufacturers (Amneal, Mylan, Teva)
Market entry barriers are low; multiple manufacturers compete on price, with few patent restrictions due to expiration.
Regulatory Environment
The original patent for Wellbutrin SR expired in 2011. Since then, generics have dominated the market. Continued biosimilar or specialty formulations are not prevalent for this drug class.
Price Trends and Projections
Historical Pricing Data
| Year |
Average Wholesale Price (AWP) per 100 mg tablet |
Notes |
| 2020 |
USD 0.25 |
Sustained competition keeps prices low |
| 2021 |
USD 0.23 |
Slight decrease, volume-driven |
| 2022 |
USD 0.20 |
Price stabilizes under increased competition |
Current Price (2023)
The average market price for the generic 100 mg extended-release tablet is approximately USD 0.20 per tablet at wholesale levels. Retail prices are typically 15–30% higher.
Price Projections (2024-2028)
| Year |
Estimated AWP per 100 mg tablet |
Assumptions |
| 2024 |
USD 0.19 |
Market saturation, stable demand |
| 2025 |
USD 0.18 |
Increased manufacturing efficiency |
| 2026 |
USD 0.17 |
Entry of price-competitor generics, further competition |
| 2027 |
USD 0.16 |
Ongoing volume growth, no new formulations |
| 2028 |
USD 0.15 |
Marginal price reduction, price wars persist |
Influencing Factors
- Market competition: Intensifies with new generics, driving prices downward.
- Manufacturing costs: Slight declines due to economies of scale and supply chain maturity.
- Regulatory activities: No major new regulations expected; patent litigation minimal.
- Prescriber trends: Steady demand for depression treatment continues.
Revenue Forecasts
Assuming an average of 15 million prescriptions annually in the US, with approximately 90 tablets per prescription:
| Year |
Projected Prescriptions |
Revenue (USD, at USD 0.20 per tablet) |
| 2023 |
15 million |
USD 540 million |
| 2024 |
15.5 million |
USD 558 million |
| 2025 |
16 million |
USD 576 million |
| 2026 |
16.5 million |
USD 594 million |
| 2027 |
17 million |
USD 612 million |
| 2028 |
17.5 million |
USD 630 million |
Note
Prices are for wholesale levels; retail prices are approximately 20–30% higher, impacting end-consumer costs more than manufacturer revenues.
Key Market Drivers
- Growing prevalence of depression and smoking cessation programs.
- Cost-effective generics eroding branded sales.
- Prescriber preference for extended-release formulations based on patient compliance.
Potential Risks
- Market saturation from multiple generics.
- Regulatory changes restricting off-label uses.
- Price erosion due to increased competition.
Key Takeaways
- The market for NDC 71093-0138 is mature, with stable demand.
- Prices are declining gradually, with projected median prices of USD 0.15–0.19 per 100 mg tablet by 2028.
- Revenues will predominantly rely on volume growth, which remains modest.
- Competition is likely to keep profit margins compressed.
FAQs
What factors influence the price of the generic bupropion product?
Market competition, manufacturing costs, supply chain dynamics, and regulatory policies are primary influences.
How does the expiration of patent rights affect pricing?
Patent expiry opens the market to generic competitors, leading to price reductions driven by increased competition.
Are there upcoming regulatory changes that could impact this drug?
No significant regulatory changes are anticipated for this drug class within the forecast period.
What is the potential of biosimilars or novel formulations?
Biosimilars are not applicable; no new formulations are currently in advanced development stages.
How does market size impact potential profitability?
A larger prescription volume stabilizes revenues even as unit prices decline, maintaining profitability for established manufacturers.
References
[1] IQVIA. (2022). Prescription Data and Market Trends.
[2] Evaluate Pharma. (2022). Global antidepressant market report.
[3] U.S. Food & Drug Administration. (2021). Patent Expiry and Generic Entry Data.
[4] Medications and Pricing Data (2023). Wholesaler and Retail Price Reports.
[5] IMS Health. (2021). Pharmaceutical Market Dynamics.
