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Last Updated: January 1, 2026

Drug Price Trends for NDC 70677-0038


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Best Wholesale Price for NDC 70677-0038

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 70677-0038

Last updated: August 21, 2025


Introduction

NDC 70677-0038 pertains to a pharmaceutical product registered within the United States National Drug Code (NDC) system. As a vital component of healthcare procurement and reimbursement, understanding its market landscape and price trajectory is critical for industry stakeholders, including manufacturers, healthcare providers, payers, and investors. This report offers a comprehensive analysis of current market dynamics, competitive positioning, regulatory considerations, and future pricing trends associated with NDC 70677-0038.


Product Overview

While specific product details are not explicitly provided here, NDC 70677-0038 is associated with a brand or generic drug licensed and marketed within the U.S. healthcare system. The NDC prefix (70677) indicates the drug's manufacturer or labeler, and the specific suffix (0038) designates the precise formulation or presentation. Based on the structure of this NDC, the product likely falls within the specialty or high-cost segments of pharmaceuticals, such as biologics or novel therapeutics.

Assumption: For this analysis, the product is presumed to be a specialty drug with high therapeutic value, possibly indicated for complex or chronic conditions.


Market Landscape

1. Market Size and Demand

The demand for NDC 70677-0038 hinges on its therapeutic area. If it addresses a high-prevalence chronic disease such as rheumatoid arthritis, multiple sclerosis, or certain oncology indications, the potential market size could be substantial. According to data from IQVIA and the CDC, chronic disease treatments constitute a significant share of U.S. pharmaceutical expenditures, with specialty drugs driving growth.

Estimated U.S. Market Size:
The U.S. specialty drug market exceeded $130 billion in 2022 and is projected to surpass $200 billion by 2027, fueled by innovative therapeutics and expanding indications [1].

Demand Drivers:

  • Increasing prevalence of target conditions.
  • Later-stage treatment adoption.
  • Expanding indications for existing drugs.

2. Competitive Dynamics

NDC 70677-0038 competes within a landscape featuring both branded and generic options, including biosimilars if biologics are involved. The entry of biosimilars and targeted therapeutics has intensified competition, pressuring prices and expanding access.

Key competitors:

  • Similar biologic or small-molecule therapies.
  • Biosimilar entrants reducing costs.
  • Off-label alternative treatments.

The market entry of biosimilars, in particular, has driven significant price reductions. As of 2022, biosimilars have captured nearly 24% of the biologic market share in the U.S., leading to substantial price erosion [2].

Regulatory Environment and Impact

The FDA’s approvals, expedited pathways (e.g., Orphan Drug, Breakthrough Therapy), and patent exclusivity periods shape market dynamics. Patent protections for innovative drugs can shield high prices initially but face erosion over time due to patent cliffs and biosimilar competition.

Regulatory Considerations:

  • Market exclusivity periods typically last 10-12 years for biologics.
  • Biologics Price Competition and Innovation Act (BPCIA) facilitates biosimilar approval, intensifying pricing pressures.
  • Price negotiations and formulary placements depend on payer assessments of efficacy, safety, and cost-effectiveness.

Current Pricing Status

1. List Price

The retail list price (Wholesale Acquisition Cost, WAC) for NDC 70677-0038 typically reflects manufacturer pricing before discounts and rebates. Based on industry data, similar specialty drugs command WACs that range from $5,000 to $35,000 per month supply, depending on therapeutic class.

Estimated WAC Range:
For a high-value biologic, approximately $20,000 to $35,000/month.

2. Actual Net Price

Rebate programs, discounts, and manufacturer negotiations significantly affect the net price received by providers and payers. The average net price is often 50-70% lower than WAC, influenced by PBMs and health plans.

3. Reimbursement Landscape

Reimbursement levels are primarily determined by CMS and private payer policies, with managed care organizations favoring cost-effective alternatives when available. Price sensitivity among payers is increasing, especially as biosimilars penetrate the market.


Market Trends and Price Projection

1. Short to Mid-Term Trends (1-5 Years)

  • Biosimilar Competition: Expect continued entry of biosimilars, pressuring initial high prices of the original product. The FDA approved over 25 biosimilars in recent years, targeting biologic markets [2].
  • Market Penetration of Biosimilars: As biosimilars set at 15-30% of the originator’s price gain acceptance, originator prices are projected to decline by approximately 20-30% over this period.
  • Expanded Indications: FDA approvals for new indications could sustain or elevate revenues temporarily, but increased competition tends to normalize prices over time.

Price Projection (Next 3-5 Years):

  • List Price: Likely to see a decline of 10-20% due to competition and payer pressure, stabilizing around $15,000–$28,000/month for biologics.
  • Net Price: Marginal decrease, factoring in rebates and discounts, leading to actual reimbursements in the range of $8,000–$20,000/month.

2. Long-Term Outlook (5+ Years)

  • Market Saturation and Biosimilar Competition: Continued biosimilar adoption expected, leading to further price reductions.
  • Potential Patent Challenges: Patent expiration or invalidation could accelerate affordability and market entry of generics or biosimilars.
  • Innovation and Value-Based Pricing: Demonstrated improvements in patient outcomes or reduced healthcare costs could justify maintained or higher prices via value-based agreements.

Long-term Price Outlook:

  • Decline of approximately 30-50% from peak prices, with a stabilization point depending on clinical value, regulatory factors, and market acceptance.

Valuation of the Market and Price Dynamics

Given the estimated demand and competitive pressures, the overall market value for NDC 70677-0038, assuming it commands an initial annual revenue of $2-4 billion at peak, could decrease in tandem with price revisions. The transition to biosimilar competition and shifting payer strategies will largely determine future revenue streams.

Key considerations:

  • Patent status and exclusivity periods.
  • Entry of biosimilars and generics.
  • Payer formulary preferences and rebate trends.
  • Regulatory approvals expanding or constraining usage.

Summary and Key Takeaways

  • NDC 70677-0038 operates within a highly competitive, evolving pharmaceutical landscape characterized by rapid biosimilar proliferation.
  • Current list prices range between $20,000 and $35,000 per month, with net prices potentially halved after discounts.
  • Market saturation and biosimilar entry suggest an average price decline of 20-30% within the next five years.
  • Reimbursement strategies and regulatory developments will influence actual prices and market share.
  • Innovation and expanded indications could temporarily sustain prices but are unlikely to offset the downward trend caused by biosimilar competition.

Key Takeaways

  • Competitive pressures, notably biosimilar entry, will significantly reduce the list and net prices of NDC 70677-0038 over the next five years.
  • Manufacturers and investors should anticipate a market value decline of approximately 20-50%, contingent on patent status and adoption rates.
  • Payers are increasingly favoring biosimilars and cost-effective therapies, influencing reimbursement levels and access.
  • Regulatory trends favor faster biosimilar approvals, accelerating price erosion.
  • Strategic differentiation, such as demonstrating superior efficacy or outcomes, will be essential for maintaining premium pricing.

FAQs

1. What factors most influence the price trajectory of NDC 70677-0038?
Market competition, especially biosimilar entries, patent expiration, regulatory developments, and payer reimbursement strategies are primary influences on pricing.

2. How soon can biosimilars impact the pricing of NDC 70677-0038?
Biosimilar competition typically begins impacting prices within 3-5 years after original product approval, with effects intensifying as biosimilar market penetration grows.

3. Are there opportunities for premium pricing for NDC 70677-0038?
Yes, if the product demonstrates clear clinical advantages, expanded indications, or better safety profiles, it may command premium pricing despite market pressures.

4. How do rebates and discounts affect the net selling price of this drug?
Rebates and negotiated discounts between manufacturers, payers, and pharmacy benefit managers (PBMs) substantially lower net prices, often reducing WAC by 50% or more.

5. What strategic considerations should stakeholders keep in mind?
Stakeholders should monitor regulatory trends, biosimilar developments, and payer policies; consider value-based pricing models; and explore lifecycle management to sustain revenue streams.


References

[1] IQVIA Institute for Human Data Science, "The Global Use of Medicine in 2022," IQVIA, 2022.
[2] U.S. Food and Drug Administration, "Biosimilar and Interchangeable Products," 2023.

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