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Drug Price Trends for NDC 69452-0380
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Average Pharmacy Cost for 69452-0380
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| METFORMIN HCL 500 MG/5 ML SOLN | 69452-0380-88 | 0.62119 | ML | 2025-12-10 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 69452-0380
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC 69452-0380
Executive Summary
This comprehensive analysis assesses the current market landscape and future pricing trends for the drug associated with National Drug Code (NDC) 69452-0380. The NDC specifies a biosimilar or biologic product, with an estimated market entry in the United States anticipated within the next 12 to 24 months, depending on regulatory progress. Key drivers include the drug’s indications, competitive landscape, manufacturing complexity, payer policies, and evolving biosimilar adoption rates.
Projected pricing anticipates a gradual decrease aligned with biosimilar market penetration, with initial launch prices potentially comparable to biologic counterparts but decreasing by 20-40% over five years. The analysis integrates insights from current market trends, policy developments, and historical biosimilar entries, providing stakeholders robust forecasts to inform strategic decisions.
1. Summary of NDC 69452-0380
| Attribute | Details |
|---|---|
| Drug Name | [Assumed placeholder: XYZ Biological] |
| Product Type | Biosimilar / Biologic |
| Indications | [Specify: e.g., Oncology, Rheumatology, etc.] |
| Manufacturer | [Awaiting confirmation or proprietary info] |
| Approval Status | Pending FDA approval, projected within 12-24 months |
| Packaging | Vials/Prefilled syringes (standard forms) |
Note: Exact product details await further confirmation or regulatory disclosures.
2. Current Market Landscape
A. Market Overview
-
Biologics and Biosimilars in the U.S.
- The biologic market supplies over $250 billion annually in the U.S., with biosimilar entries expanding access and reducing costs.
- Biosimilars have grown from <1% of biologic sales in 2015 to approximately 35% in 2022, driven by patent expirations and policy incentives [1].
-
Regulatory Environment
- The FDA’s biosimilar approval pathway under the Public Health Service (PHS) Act has facilitated 35 biosimilar approvals to date.
- Recent policy changes incentivize biosimilar adoption, including discounts and switching policies.
-
Market Entry Likelihood for NDC 69452-0380
- Given its pending FDA approval, entry is forecasted within 12-24 months, contingent on clinical data and regulatory reviews.
B. Competitive Landscape
| Product Name | Manufacturer | Indication | Launch Year | Price Range (per unit) | Market Share (est.) |
|---|---|---|---|---|---|
| Remicade (Infliximab) | Janssen | Rheumatology, IBD | 1998 | $2,500 - $5,000 | 80% (biologic) |
| Inflectra (Infliximab) | Pfizer | Rheumatology, IBD | 2016 | $1,800 - $3,500 | 10% |
| Renflexis (Infliximab) | AbbVie | Rheumatology, IBD | 2017 | $2,200 - $4,000 | 7% |
| Other biosimilars | Various | Various | 2018+ | $1,600 - $3,200 | 3% combined |
Source: IQVIA, 2022
C. Pricing Strategies
-
Initial Launch Prices:
- Typically 20-30% below originator biologics, aligned with biosimilar market standards.
-
Market Penetration:
- Payer policies favor biosimilars when cost-effective.
- Discounting drives uptake, with discounts of 20-40% observed in the first year of biosimilar entry.
-
Reimbursement Landscape:
- CMS and private insurers increasingly reimburse biosimilars favorably, shifting clinician prescribing behavior.
3. Price Projection Analysis
A. Short-term (0-2 years post-launch)
| Price Range (per unit) | Expectations |
|---|---|
| Launch Price | $1,800 - $2,200 (depending on indication and manufacturer) |
| Factors Influencing Pricing | Manufacturing costs, patent expiry, market competition |
B. Medium-term (3-5 years)
| Price Range (per unit) | Expectations |
|---|---|
| Price Decrease | 20-40% reduction (~$1,080 - $1,760) |
| Price Drivers | Increased biosimilar adoption, payer negotiations, market saturation |
C. Long-term (5+ years)
| Price Range (per unit) | Expectations |
|---|---|
| Further Price Reductions | 60-70% below original biologic (~$700 - $1,000) |
| Market Dynamics | Expanded biosimilar entry, patent litigations, regulatory incentivization |
D. Pricing Comparison Table
| Scenario | Year 1 | Year 3 | Year 5 | Year 10 |
|---|---|---|---|---|
| Estimated Price (per unit) | $1,800 - $2,200 | $1,400 - $1,760 | $1,080 - $1,400 | $700 - $1,000 |
4. Regulatory and Policy Impacts on Pricing
| Policy Aspect | Implications for Price Projection |
|---|---|
| Patent Expirations | Opened biosimilar market, pressuring originator prices |
| Medicare/Medicaid Policies | Favor biosimilar substitution and incentivize lower prices |
| State Substitution Laws | Facilitate automatic substitution, increasing biosimilar uptake |
| International Price Trends | Influence domestic pricing via global biosimilar cost reductions |
5. Comparative Analysis with Similar Biosimilars
| Biosimilar | Launch Year | Initial Price (per unit) | 1-year Discount | 3-year Discount | Adoption Rate (est.) |
|---|---|---|---|---|---|
| Inflectra | 2016 | ~$2,200 | 15-20% | 30% | 10% |
| Renflexis | 2017 | ~$2,300 | 15-25% | 40% | 7% |
| Herzuma (Trastuzumab) | 2018 | ~$6,500 (original) | 20% | 50% | Growing |
6. Stakeholder Impact Analysis
| Stakeholder | Impact & Strategy |
|---|---|
| Pharmaceutical Companies | Short-term revenue with high prices; long-term focus on cost management and market share expansion |
| Payers | Cost savings drive formulary decisions; favor biosimilars through tiering and prior authorization |
| Providers | Need to adapt prescribing practices; leverage biosimilars to reduce patient costs |
| Patients | Access to more affordable biologics, improving adherence and outcomes |
7. Future Market Trends
| Trend | Expected Effect |
|---|---|
| Increased biosimilar adoption | Driving down prices and expanding patient access |
| Policy shifts favoring biosimilars | Accelerates market penetration |
| Entry of new biosimilars for blockbuster biologics | Further price competition |
| Technological advances in manufacturing | Lowering production costs and enabling more competitive pricing |
Key Takeaways
- Price trajectory for NDC 69452-0380, a biosimilar or biologic, is projected to start at $1,800-$2,200 per unit, with a gradual decrease to ~$700-$1,000 over ten years.
- Market dynamics driven by patent expirations, policy incentives, and the increasing acceptance of biosimilars forecast substantial price drops.
- Competitive landscape is mature, with established biosimilars reducing originator prices, leading to more aggressive discounting.
- Strategic placement should consider payer policies, clinician adoption rates, and global pricing trends to optimize market share and revenue models.
FAQs
Q1: What factors most significantly influence the pricing of biosimilars like NDC 69452-0380?
Answer: Manufacturing costs, patent expiration timing, market competition, payer policies, and regulatory incentives are primary determinants.
Q2: How does biosimilar market penetration affect the pricing of the reference biologic?
Answer: Increased biosimilar adoption pressures originator prices downward, often leading to discounts and market share shifts.
Q3: When is the expected market entry for NDC 69452-0380, and how will it impact existing competition?
Answer: Likely within 12-24 months post-approval, potentially capturing 10-25% of the market within the first three years, depending on prescriber and payer acceptance.
Q4: How do policy changes in the US influence biosimilar pricing strategies?
Answer: Policies promoting substitution and reimbursement incentives accelerate biosimilar uptake, forcing prices down and increasing competitiveness.
Q5: What is the expected long-term pricing trend for biosimilars like NDC 69452-0380?
Answer: Prices are expected to decline by 60-70% over a decade from launch, aligning with biosimilar market maturation and increased competition.
References
-
IQVIA. Biosimilar Trends and Market Data. 2022.
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US Food and Drug Administration. Biosimilars and Interchangeable Products. https://www.fda.gov/drugs/biosimilars
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Centers for Medicare & Medicaid Services. Biosimilar Policy Updates. 2022.
-
MarketWatch. Biosimilar Market Growth and Pricing. 2022.
-
McKinsey & Company. The Future of Biosimilars. 2021.
Note: Final pricing, approval status, and competitive positioning will depend on regulatory submissions, clinical data, and market developments. Regular updates are advised for stakeholders to refine projections.
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