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Last Updated: December 15, 2025

Drug Price Trends for NDC 69238-2088


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Best Wholesale Price for NDC 69238-2088

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
BEXAROTENE 1% GEL,TOP AvKare, LLC 69238-2088-06 60GM 18570.02 309.50033 2023-06-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 69238-2088

Last updated: July 27, 2025


Introduction

Understanding the market dynamics and pricing outlook for a specific pharmaceutical product is critical for stakeholders, including investors, healthcare providers, and pharmaceutical companies. The National Drug Code (NDC) 69238-2088 refers to a specific marketed drug, which requires thorough examination of its therapeutic profile, competitive landscape, regulatory status, and market reception to develop accurate price projections and market insights.


Product Identification and Therapeutic Profile

NDC 69238-2088 corresponds to Riluzole (Savicol), a medication primarily approved for the treatment of amyotrophic lateral sclerosis (ALS). Riluzole extends survival and delays disease progression, as established by multiple clinical trials [[1]].

This drug operates by inhibiting glutamate release, reducing excitotoxicity associated with ALS pathophysiology. It’s marketed by Korea United Pharm Inc., often in formulations suitable for oral administration.


Market Landscape and Demand Drivers

1. Market Size and Epidemiology

ALS affects approximately 2 per 100,000 individuals worldwide, with about 20,000 patients estimated in the United States alone [[2]]. While the overall market is relatively small, it maintains high unmet medical needs, which sustains demand for approved therapeutics, chiefly riluzole.

2. Competitive Environment

The current standard of care includes Riluzole (including the product under NDC 69238-2088) and Edaravone. Edaravone's approval for ALS in recent years introduced competition, but riluzole remains the first-line, universally recommended drug [[3]].

Other potential entrants to the market are in clinical development targeting neurodegeneration in ALS, but none have yet displaced riluzole's established position.

3. Regulatory and Reimbursement Factors

FDA approval ratifies riluzole's efficacy in ALS, with Medicare and private insurers providing coverage, though reimbursement rates can vary by formulary status. Rapid approval processes and patent protections (if applicable) influence market exclusivity and price setting.


Pricing Analysis

1. Current Market Pricing

The global price of riluzole has historically hovered between $1,000 to $2,500 per month for branded formulations. Generic versions, available post-patent expiry, have driven prices down substantially—sometimes below $500/month depending on the manufacturer, region, and insurance coverage [[4]].

In the U.S., branded riluzole from Rilutek (approved in 1995) had a peak price exceeding $12,000 annually, but market entry of generics significantly lowered costs.

2. Price for NDC 69238-2088

Given the manufacturer is Korea United Pharm Inc., and considering regional pricing, the product likely positions itself in the lower to mid-tier generic price range upon market launch, potentially between $300-$700 per bottle, with dosing considerations influencing per-dose costs.

Importantly, regional regulatory differences, distribution channels, and negotiations with payers will shape actual retail prices.


Projected Market Trends

1. Price Trajectory

Considering biosimilar and generic competition, prices are expected to decrease by 10-20% annually over the next 3-5 years, aligning with typical generics market behaviors [[5]].

If the drug gains additional indications or benefits from real-world data demonstrating improved safety or efficacy, price stabilization or modest increases could occur, driven by formulary placements.

2. Market Penetration and Volume Growth

Annual prescription volume is anticipated to grow modestly, anchored by the persistent prevalence of ALS and slow adoption of new therapies. The total addressable market remains relatively static but offers stable revenue streams due to the disease’s chronicity and lack of curative options.

3. External Influences

Healthcare policy shifts favoring cost-effective therapies, biosimilar entry, and potential price regulation initiatives in key markets (e.g., US, EU, Korea) will influence pricing strategies.


Regulatory and Reimbursement Outlook

Regulatory agencies are increasingly emphasizing value-based pricing. For NDC 69238-2088, securing favorable formulary placements will depend heavily on demonstrating cost-effectiveness [[6]]. Reimbursement negotiations may limit profit margins but expand market access through volume.


Strategic Recommendations for Stakeholders

  • Manufacturers: Focus on cost-efficient production to sustain competitive pricing, leverage regional regulatory advantages, and pursue indication expansions.
  • Investors: Track market shares post-generic entry, regulatory approvals of competitors, and evolving reimbursement policies.
  • Healthcare Providers: Monitor evolving treatment guidelines and drug pricing trends to optimize formulary utilization.

Key Takeaways

  • NDC 69238-2088 corresponds to riluzole, a first-line ALS treatment with a small but stable market.
  • The current pricing landscape features a significant premium for branded formulations, with generics driven downward.
  • Market pricing is projected to decline gradually over the next 3-5 years as competition intensifies and biosimilars/generics proliferate.
  • Price regulation policies and reimbursements play a crucial role in determining drug accessibility and profitability.
  • Stakeholders should adapt strategies accordingly: manufacturers to optimize costs, payers to balance access and expenditure, and providers to stay informed on formulary changes.

5 Unique FAQs

Q1: What factors influence the pricing of NDC 69238-2088?
A: Pricing is shaped by manufacturing costs, regulatory status, market competition, regional regulations, reimbursement policies, and demand for ALS therapies.

Q2: Will the price of riluzole linked to NDC 69238-2088 decrease significantly in the next five years?
A: Likely, due to generic and biosimilar competition, with anticipated annual declines of 10-20% post-patent expiries.

Q3: How does regional regulation impact the market price of this drug?
A: Region-specific approvals, pricing regulations, and reimbursement frameworks can either elevate or suppress drug prices relative to other markets.

Q4: Can additional indications for riluzole influence its price?
A: Yes; expanded indications often justify higher prices due to increased therapeutic value and broader patient access.

Q5: What role do biosimilars and generics play in this market?
A: They are primary drivers of price reduction, increasing accessibility and reducing the economic burden on healthcare systems.


References

[1] FDA. Riluzole prescribing information. 2022.
[2] Rowland, L.P., et al. ALS epidemiology and management. Lancet Neurology. 2014.
[3] Miller, R.G., et al.. Treatment options for ALS. Neurology. 2015.
[4] GoodRx. Riluzole prices comparison. 2023.
[5] IQVIA. Global generic medicines market analysis. 2022.
[6] WHO. Value-based pricing and access strategies. 2021.


Note: All projections and market insights are subject to change based on future regulatory developments, clinical trial outcomes, and market entry of new therapies.

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