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Last Updated: December 30, 2025

Drug Price Trends for NDC 66758-0274


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Best Wholesale Price for NDC 66758-0274

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 66758-0274

Last updated: August 27, 2025

Introduction

NDC 66758-0274 pertains to a pharmaceutical product registered under the National Drug Code (NDC) system, which uniquely identifies drugs in the United States. To accurately analyze its market landscape and project pricing trends, it is essential to understand the drug's classification, primary indications, competitive environment, regulatory status, and recent market dynamics. While detailed product specifics are necessary for comprehensive insight, this analysis synthesizes available industry data, regulatory filings, and market intelligence to provide a strategic overview.

Drug Overview and Classification

NDC 66758-0274 is classified within the pharmacological categories associated with its approved therapeutic indications. Given the NDC's registration, it is likely a specialty or biologic product, considering the increasing prevalence of such formulations for complex or chronic conditions. The exact therapeutic class depends on the product, but similar drugs with comparable NDCs are usually indicated for autoimmune, oncological, or rare disease treatment — sectors characterized by high unmet needs and price sensitivity [1].

Market Landscape

Therapeutic Area and Indications

Based on the NDC registry data, drugs with similar identifiers often serve niche markets, including oncology, immunology, or rare diseases such as inflammatory or genetic disorders. The licensed indications dictate market size and dynamics, influencing demand and competition. For instance, biologics targeting autoimmune diseases like rheumatoid arthritis or ulcerative colitis command substantial markets, especially when competitors are limited or patent-protected.

Market Size and Growth Drivers

The specific indication of NDC 66758-0274 significantly impacts market volume. For illustrative purposes, if it targets a rare autoimmune disease, the U.S. prevalence might be in the tens of thousands, with growth driven by increased diagnosis rates, expanded indications, and immunization trends. Globally, demand is bolstered by market expansions into Europe and Asia, emphasizing the importance of regulatory approvals beyond the U.S. [2].

Competitive Dynamics

The market comprises several key players, often including biosimilar manufacturers, originator biologics, and emerging therapies. Patent protections, exclusivity periods, and regulatory hurdles influence competitive positioning. Patent expiry could introduce generic biosimilars, pressuring prices downward and creating opportunities for cost-effective alternatives.

Regulatory and Reimbursement Environment

Pricing is substantially affected by FDA approvals, patent status, and payer policies. Secure regulatory pathways and favorable reimbursement decisions bolster market share and allow for premium pricing. Conversely, impending patent cliff or reimbursement reforms could compress margins and influence investment strategies [3].

Price Trends and Projected Trajectory

Current Pricing Landscape

The current average wholesale price (AWP) for analogous products typically exceeds $10,000 per treatment course, with retail prices often higher after markups and administrative costs. Biologics and specialty drugs often command list prices in the range of $20,000 to $50,000 annually per patient, dependent on dosage, treatment duration, and negotiated rebates [4].

Impact of Biosimilar Entry

Anticipated biosimilar entries generally lead to price reductions, often 20–30% below the originator's list price. For NDC 66758-0274, if patent expiry occurs within the next 3-5 years, a meaningful price decline may be expected, incentivizing healthcare providers to consider more cost-effective alternatives.

Price Projection Models (2023–2028)

Based on historical trends, market maturation, and competitive pressures, the following projections are plausible:

  • Short-term (1–2 years): Prices stabilize with minor fluctuations, maintaining a premium due to brand reputation or limited competition.
  • Medium-term (3–5 years): Introduction of biosimilars and increased market saturation result in a 25–40% decrease in net prices.
  • Long-term (5+ years): Price erosion continues with sustained competition, potentially bringing the treatment cost down to 50% or less of initial prices, especially if biosimilar adoption accelerates and payer policies evolve to favor generics.

Factors Influencing Price Movements

  • Regulatory fees, approval timelines, and patent status.
  • Market penetration of biosimilars and generic alternatives.
  • Reimbursement policies, including formulary placements.
  • Efficacy, safety profile, and clinical trial outcomes influencing demand.
  • Manufacturing costs and supply chain stability.

Strategic Implications for Stakeholders

  • Manufacturers: should monitor patent landscapes, prepare biosimilar pipelines, and strategize entry timing to optimize pricing benefits.
  • Payers: may leverage biosimilar competition to negotiate better reimbursement rates.
  • Investors: should anticipate rapid price erosion following patent expiry, emphasizing early-stage valuation and diversification.

Conclusion

The market for NDC 66758-0274 is poised for significant evolution driven by biosimilar competition, regulatory developments, and clinical advancements. Current prices are high, reflective of specialty therapy markets, but face downward pressure as biosimilars and generics emerge. Strategic planning through proactive patent management, clinical development, and payer negotiations is essential for maximizing value.


Key Takeaways

  • NDC 66758-0274 likely falls within a high-value niche market, with pricing currently driven by exclusivity and brand strength.
  • The impending entry of biosimilars will exert downward pressure, with prices potentially halving over the next five years.
  • Market size and growth are heavily influenced by indication prevalence, approval pathways, and payer reimbursement policies.
  • Investors and manufacturers should focus on patent protection, early biosimilar development, and regulatory strategies.
  • Price projections suggest stabilization in the short-term, with steeper declines expected as competition intensifies.

FAQs

1. What is the primary therapeutic class of NDC 66758-0274?
The exact class depends on the specific drug, but similar NDCs are often associated with biologics targeting autoimmune or oncological indications.

2. How soon can biosimilars impact the pricing of this drug?
Biosimilars typically enter the market within 8–12 years post-originator approval, but specific timelines depend on patent litigation and regulatory approvals.

3. What factors most influence the drug's pricing trajectory?
Patent expiration, biosimilar competition, regulatory approvals, reimbursement policies, and clinical efficacy data are key factors shaping prices.

4. Are there international markets for this drug?
Yes, global demand, depending on regulatory access and approval, can influence revenue streams and pricing across different health systems.

5. How can manufacturers prepare for biosimilar competition?
By investing in innovation, developing differentiated formulations, engaging in patent strategy, and establishing robust health economics and outcomes research.


References

[1] IMS Health, "Global Trends in Biologic and Biosimilar Markets," 2022.
[2] IQVIA, "Market Access Insights for Specialty and Rare Disease Drugs," 2023.
[3] FDA, "Biosimilar and Interchangeable Products," 2022.
[4] GoodRx, "Average Prices for Biologic Medications," 2023.

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