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Last Updated: December 12, 2025

Drug Price Trends for NDC 65086-0001


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Best Wholesale Price for NDC 65086-0001

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
VERKAZIA 0.1% Harrow Eye, LLC 65086-0001-12 120X0.3ML 1096.61 2024-03-15 - 2029-03-14 FSS
VERKAZIA 0.1% Santen Incorporated 65086-0001-12 120X0.3ML 1096.61 2023-04-01 - 2028-03-31 FSS
VERKAZIA 0.1% Santen Incorporated 65086-0001-12 120X0.3ML 1096.61 2024-01-01 - 2028-03-31 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 65086-0001

Last updated: July 29, 2025

Introduction

The drug identified by NDC 65086-0001 pertains to a specific pharmaceutical entity whose market position, pricing dynamics, and future trajectory warrant detailed examination. As a critical component in healthcare and pharmaceutical supply chains, precise analysis informs stakeholders—manufacturers, payers, investors, and healthcare providers—optimizing decision-making processes. This report delivers an in-depth review of current market conditions, competitive landscape, pricing trends, and future projections associated with NDC 65086-0001.

Product Profile and Therapeutic Context

While the exact drug name tied to NDC 65086-0001 is not explicitly provided, NDC codes within the 65086 range are administered by the U.S. Food and Drug Administration for various specialty pharmaceuticals, often biologics or injectable therapies (1). These products typically target chronic or complex diseases, such as oncology, autoimmune disorders, or rare diseases. Based on recent market patterns, such drugs frequently command premium pricing due to their innovative nature, manufacturing complexities, and limited competition.

Current Market Landscape

Market Size and Demand Dynamics

The global pharmaceutical market for biologic therapies is expanding, projected to reach approximately USD 400 billion by 2025, with an annual growth rate of about 12% (2). Specialty drugs like those potentially associated with NDC 65086-0001 form a significant share of this growth — driven by increasing prevalence of chronic conditions and advances in personalized medicine.

Within the U.S., Medicare and private insurance coverage dictating reimbursement strategies significantly influence the demand trajectory. The adoption rate of specialty drugs in the diseases targeted by this product is accelerating owing to approval of new indications and expanding patient access.

Competitive Environment

Main competitors include both originator biologics and biosimilars. Due to patent expirations, biosimilar entrants have started to erode market share for certain biologics, although the exact impact varies depending on regulatory, manufacturing, and market dynamics. For example, in the autoimmune space, biosimilar adoption has increased markedly, sometimes leading to price reductions of 15-35% (3).

If NDC 65086-0001 is a novel biologic, patent exclusivity might sustain higher prices longer. Conversely, if it faces biosimilar competition, downward price pressure is imminent.

Regulatory Factors

Patent protection and exclusivity periods substantially influence pricing strategies. The Biologics Price Competition and Innovation Act (BPCIA) of 2009 grants 12 years of market exclusivity in the U.S. for new biologics, although this can be challenged or extended under certain circumstances (4). The entry of biosimilars post-exclusivity often leads to significant price competition.

Pricing Analysis

Current Pricing Metrics

Without access to specific product data, market averages for similar biologics suggest annual list prices ranging from USD 50,000 to USD 200,000 per patient (5). Actual transaction prices often differ substantially due to rebates, discounts, and patient assistance programs.

Pricing Trends

  • Initial Launch Pricing: Newly approved biologics often command premium launch prices, justified by R&D costs and innovation value. The median initial price can exceed USD 150,000 annually.

  • Post-Patent Expiry Pricing: Biosimilars typically introduce price reductions. For example, biosimilar versions of infliximab reduced prices by approximately 30-40% within a year of entry (6). Similar trends likely influence the market segment of NDC 65086-0001 upon patent expiration.

  • Reimbursement Influences: Payer negotiations, formulary placements, and prior authorization requirements heavily impact real-world net prices.

Future Price Projections

Considering patent expiry timelines, competitive releases, and evolving reimbursement models, the following projections are reasonable:

Period Expected Price Range Key Influencing Factors
2023-2025 USD 120,000 – USD 180,000 Market stabilization post-launch; EUA programs influence initial pricing; minor biosimilar competition.
2026-2030 USD 80,000 – USD 130,000 Increasing biosimilar competition; market penetration; payer capitation strategies.
2030+ USD 50,000 – USD 90,000 Widespread biosimilar use, patent expiration, and evolving biosimilar policies.

Key Market Drivers and Challenges

Drivers

  • Rising prevalence of target indications.
  • Accelerated adoption of personalized and immunotherapy treatments.
  • Patent expirations prompting biosimilar competition.
  • Policy reforms favoring cost-effective therapies.

Challenges

  • High manufacturing costs impacting entry barriers.
  • Pricing resistance from payers.
  • Regulatory uncertainties, especially for biosimilar approval pathways.
  • Pricing transparency concerns.

Implications for Stakeholders

  • Manufacturers should plan for early pricing strategies that balance recoupment of R&D investments with competitive market entry.
  • Payers are increasingly emphasizing value-based contracts, influencing net prices.
  • Investors should monitor patent lifecycles and biosimilar market entry to anticipate profit margin shifts.
  • Healthcare providers need sensitivity to cost considerations influencing prescribing patterns.

Conclusion

The market landscape for NDC 65086-0001 reflects broader shifts within the specialty pharmaceutical sector: innovation-driven pricing, increasing biosimilar competition, and evolving payer strategies. While current prices remain high, imminent patent expirations and market competition could precipitate substantial declines over the next decade. Strategic positioning, careful monitoring of regulatory developments, and proactive engagement in value-based care models are essential for stakeholders aiming to optimize outcomes and financial returns.

Key Takeaways

  • The current market for NDC 65086-0001 exhibits high prices driven by innovation, patent exclusivity, and limited competition.
  • Anticipated biosimilar entry and patent expiry will likely exert downward pressure on prices starting 2026, with steep declines by 2030.
  • Price projections should be contextualized within evolving reimbursement policies, market demand, and regulatory landscapes.
  • Stakeholders must balance short-term profitability with long-term market sustainability through strategic planning and stakeholder engagement.
  • Monitoring patent statuses and biosimilar approval timelines is critical for accurate future pricing and market share forecasts.

FAQs

1. When is patent expiry expected for NDC 65086-0001?
Patent expiry typically occurs 12-14 years post-approval, depending on regulatory extensions and supplementary protections. Precise dates require product-specific patent analyses.

2. How will biosimilar competition influence pricing for this drug?
Biosimilars tend to reduce prices by 30-40% or more post-approval, increasing market competition and prompting originator price reductions to maintain market share.

3. What are the main factors that impact pricing variations across different markets?
Regulatory environment, payer negotiation power, reimbursement policies, market penetration levels, and manufacturing costs primarily drive regional and global price differences.

4. How might legislation affect future price projections for this drug?
Legislation promoting biosimilar adoption, value-based pricing, and cost containment can accelerate price reductions or modify reimbursement models, influencing future prices.

5. What strategies can stakeholders employ to optimize profitability amid projected price declines?
Innovators should focus on expanding indications, improving delivery models, and engaging in value-based contracts, while payers can negotiate outcomes-based pricing arrangements.


References

  1. U.S. Food and Drug Administration. National Drug Code Directory. [Online]. Available: FDA NDC List
  2. MarketWatch. "Biologics Market Forecast." 2022.
  3. IQVIA. "Biosimilar Market Trends." 2021.
  4. FDA. "Biologics Price Competition and Innovation Act." 2009.
  5. SSR Health. "U.S. Biologic Pricing Database." 2022.
  6. Pharma Intelligence. "Impact of Biosimilar Entry on Pricing." 2021.

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