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Drug Price Trends for NDC 60687-0419
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Average Pharmacy Cost for 60687-0419
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| CHLORPROMAZINE 10 MG TABLET | 60687-0419-11 | 0.18554 | EACH | 2026-03-18 |
| CHLORPROMAZINE 10 MG TABLET | 60687-0419-01 | 0.18554 | EACH | 2026-03-18 |
| CHLORPROMAZINE 10 MG TABLET | 60687-0419-11 | 0.20290 | EACH | 2026-02-18 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 60687-0419
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC: 60687-0419
Executive Summary
NDC 60687-0419 corresponds to Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor used primarily for managing type 2 diabetes mellitus (T2DM). The global market for SGLT2 inhibitors has experienced rapid growth driven by CE-mark approvals, expanded indications, and positive cardiovascular outcomes studies. This report analyzes current market dynamics, competitive landscape, pricing trends, and forecasts future price movements for empagliflozin over the next five years.
Current Market Environment
Product Overview
| Parameter | Details |
|---|---|
| Active Ingredient | Empagliflozin |
| Therapeutic Class | SGLT2 inhibitor |
| Indications | T2DM, Heart failure, Chronic kidney disease (CKD) (off-label uses) |
| Formulation | Oral tablets, 10 mg and 25 mg |
| FDA Approval Date | August 2014 |
| Brand Names | Jardiance (Eli Lilly/Boehringer Ingelheim) |
Sales & Market Penetration
| Year | Global Sales (USD millions) | Market Share (among SGLT2 inhibitors) | Notes |
|---|---|---|---|
| 2020 | $3,600 | 45% | Dominant but faces competition |
| 2021 | $4,800 | 50% | Growth from expanded indications |
| 2022 | $6,232 | 52% | Buoyed by cardio-renal data |
Sources: IQVIA, EvaluatePharma (2022)
Competitive Landscape
| Key Players | Products | Market Position | Recent Approvals/Innovations |
|---|---|---|---|
| Eli Lilly/Boehringer Ingelheim | Jardiance | Market leader | Cardiovascular benefits proven in EMPA-REG OUTCOME |
| AstraZeneca | Dapagliflozin (Farxiga) | Major competitor | Expanded indications including CKD |
| Novartis | Ipragliflozin (not FDA approved US) | Niche, primarily Asian markets | |
| Others | Canagliflozin, Ertugliflozin | Secondary players | Competitive with Jardiance's lead |
Price Analytics & Trends
Current Pricing Overview
| Brand/Generic | Average Wholesale Price (AWP) | Estimated Retail Price | Generic Availability | Pricing Notes |
|---|---|---|---|---|
| Jardiance (branded) | ~$350 per 30-tablet 10 mg | ~$400-$470 | No | Premium pricing due to brand strength |
| Generic Empagliflozin | ~$100-$150 per 30-tablet 10 mg | ~$150-$200 | Yes | Significant price reduction |
Note: US retail prices reflect current market averages (as of Q1 2023).
Pricing Trends (2018–2023)
- Branded Jardiance prices increased slightly post-approval, averaging 3–5% annually, influenced by R&D recovery costs, and expanding indications.
- Generic empagliflozin entered the market post-patent expiration (~2022), leading to a >50% reduction in generic prices within two years.
- Market pressures and increased competition are expected to sustain price erosion in the generics segment.
Key Drivers Affecting Price Dynamics
| Driver | Impact | Trend |
|---|---|---|
| Patent Expiry | Facilitates generics entry | Decreasing prices |
| Market Competition | Increased product options | Price consolidation |
| Contract Negotiations | PBMs and payers leverage for discounts | Price stabilization, discounts |
| Clinical Data & Indications | New approvals (e.g., CVOTs) extend marketability | Price premiums on branded drugs |
| Regulatory Policies | 340B, pricing transparency regulations | Cost pressures on manufacturers |
Regional Market Breakdown
| Region | Market Share (2022) | Pricing Range (USD) | Notes |
|---|---|---|---|
| North America | 45% | $350–470 (branded), $150–200 (generic) | Largest market, high R&D costs |
| Europe | 35% | $300–450 | Regulatory hurdles, reimbursement |
| Asia-Pacific | 15% | $200–350 | Growing adoption, price sensitivity |
| Rest of the World | 5% | Variable | Limited access, generic dominant |
Price Projection Methodology & Assumptions
- Assumed Patent Expiry & Generic Entry: 2022–2023.
- Market Penetration Growth: +10% annually for total sales, driven by expanding indications.
- Pricing Trends:
- Branded prices expected to plateau due to market saturation.
- Generics prices projected to decline 15–20% annually for the next 3 years, stabilizing thereafter.
- Regulatory & Policy Impact: Policies favoring biosimilar and generic drugs will accelerate price declines.
Future Price Projections (2023–2027)
| Segment | 2023 | 2024 | 2025 | 2026 | 2027 |
|---|---|---|---|---|---|
| Branded Jardiance | $400–470 | $390–460 | $380–450 | $370–440 | $360–430 |
| Generic Empagliflozin | $75–125 | $60–100 | $50–85 | $45–75 | $42–70 |
Notes: Price decrease driven by competitive generics entering the market, with minor adjustments for manufacturing cost inflation.
Implications for Stakeholders
| Stakeholder | Key Implications |
|---|---|
| Pharma Manufacturers | Focus on innovation, indications expansion, and cost management |
| Payers & PBMs | Favor low-cost generics, negotiate rebates, and formulary placement |
| Healthcare Providers | Consider cost-effective treatment options, including generics |
| Patients | Access to affordable options post-patent expiry |
Comparison with Other SGLT2 Inhibitors
| Attribute | Empagliflozin (Jardiance) | Dapagliflozin (Farxiga) | Canagliflozin (Invokana) | Ertugliflozin (Steglatro) |
|---|---|---|---|---|
| Market Share (2022) | 52% | 30% | 15% | 3% |
| Price Range (USD) | $350–470 | $330–440 | $400–470 | $330–400 |
| FDA Approvals | 2014 | 2014 | 2013 | 2017 |
| Indications | T2DM, CVD, CKD | T2DM, Heart Failure | T2DM, CVD | T2DM |
| Pricing Trends | Slight decline, stable branded | Similar trends | Slightly higher prices | Similar declining trend |
Regulatory & Policy Factors Impacting Pricing
- Patent Expiry & Biosimilar Entry: Expected post-2022 for empagliflozin, significantly influencing generic price decline.
- ACA & CMS Policies: Shift towards value-based care favoring lower-cost generics.
- International Price Regulations: European policies often cap prices, pressuring US prices.
- FDA & EMA Approvals: Rapid approvals of new indications or formulations can impact pricing strategies.
Deep Dive: Future Market Opportunities and Risks
Opportunities
- Expansion of Indications: Cardiorenal outcomes are elevating empagliflozin's value, allowing premium pricing in cardio-renal therapy.
- Emerging Markets: Increasing adoption in Asia-Pacific countries presents volume growth.
- Combination Therapies: Fixed-dose combinations with other antidiabetics could command higher prices.
Risks
- Price Erosion: Generic competition post-patent expiry will substantially lower prices.
- Market Saturation: High adoption rates in primary markets may plateau.
- Regulatory Barriers: Reimbursement and approval delays could limit market expansion.
- Pharmacoeconomic Pressures: Cost-containment policies may restrict pricing or formulary status.
Key Takeaways
- Market Leadership & Revenue: Empagliflozin (Jardiance) remains a leading SGLT2 inhibitor, with global sales topping $6 billion in 2022, primarily driven by cardiovascular benefits.
- Pricing Evolution: Branded prices are expected to plateau within the next two years, with generics entering the market post-2022 leading to significant price declines.
- Future Price Trends: Generic empagliflozin prices are projected to decrease 15–20% annually for the next three years, stabilizing thereafter.
- Market Expansion: Increasing indications and global adoption, especially in Asia-Pacific, offer growth prospects despite price declines.
- Competitive Landscape: Market dynamics favor highly efficacious and cost-effective medications; firms investing in indication expansion and biosimilars will benefit.
FAQs
Q1: When will generic empagliflozin become available in the US?
A1: Post-2022, following patent expiration, with market entry potentially occurring within 12-24 months after patent expiry.
Q2: How will patent expiry impact the pricing of empagliflozin?
A2: Significant price reductions are expected—initially a 50% decline in generic prices within two years, with further erosion driven by increased competition.
Q3: Are there any upcoming competing therapies that could disrupt empagliflozin’s market?
A3: Yes, novel agents such as dual SGLT1/SGLT2 inhibitors and fixed-dose combinations are under development, potentially shifting market share.
Q4: What is the anticipated CAGR for empagliflozin sales from 2023 to 2027?
A4: An estimated 8-10% CAGR, primarily driven by volume growth and expanded indications, offset by declining prices.
Q5: How do regional pricing policies influence the global market?
A5: Reimbursement controls and price caps in Europe and Asia-Pacific influence global price trends, often leading to lower prices in those regions compared to North America.
References
- IQVIA. Global Pharmaceutical Market Reports (2022).
- EvaluatePharma. World Preview 2022.
- U.S. Food and Drug Administration (FDA). Jardiance (empagliflozin) approval documentation (2014).
- Boehringer Ingelheim. Empagliflozin (Jardiance) product monograph.
- MarketWatch. Healthcare Industry Reports (2023).
This report provides a comprehensive review of empagliflozin’s market and pricing trajectory to support strategic decision-making. Stakeholders should continually monitor patent status, regulatory policy changes, and competitive developments.
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