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Last Updated: December 28, 2025

Drug Price Trends for NDC 60429-0048


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Best Wholesale Price for NDC 60429-0048

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
NIFEDIPINE (EQV-XL) 60MG TAB,SA Golden State Medical Supply, Inc. 60429-0048-01 100 19.43 0.19430 2023-06-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 60429-0048

Last updated: July 29, 2025


Introduction

The pharmaceutical landscape continuously evolves with new formulations and competitive pricing strategies. The National Drug Code (NDC) 60429-0048 represents a specific marketed drug whose market dynamics merit detailed analysis. This report assesses the current market environment, competitive positioning, regulatory considerations, and future price projections, equipping stakeholders with insights necessary for strategic decision-making.


Product Overview

NDC 60429-0048 corresponds to a prescription medication, potentially within categories such as biologics, small-molecule drugs, or specialty therapeutics, depending on the manufacturer’s specifications. However, precise details, including indication, dosage, and formulation, are crucial. For the purposes of this analysis, assume it is a specialty drug with boutique manufacturing and limited competition, which impacts pricing and market penetration.


Market Landscape

Market Size & Penetration

The initial market size for drugs designated under NDC 60429-0048 largely depends on the prevalence of the condition it treats. For instance, if it targets rare diseases (orphan indications), the market is inherently limited but often characterized by high price points. Conversely, broader indications can translate to larger potential revenues but also intensify competition.

Based on recent data from the Centers for Disease Control and Prevention (CDC) and market research firms, the total addressable market (TAM) for similar therapeutics ranges from tens to hundreds of millions of dollars annually, subject to geographic reach, insurance coverage, and provider acceptance. Assuming early adoption phases, market penetration remains gradual, constrained by regulatory approvals, reimbursement, and physician familiarity.

Competitive Environment

Market entrants include both branded and generic competitors. For newer Drugs in the same class, patent exclusivity (generally 12–20 years in the U.S.) substantially influences pricing. Once patent expiry approaches, significant reductions in price typically occur, driven by generics and biosimilars.

In the case of NDC 60429-0048, if it benefits from patent protection and exclusivity, premium pricing can sustain for several years. If biosimilars or generics are authorized, downward price pressure is inevitable.

Reimbursement & Pricing Dynamics

Reimbursement policies heavily influence net revenue. Insurers favor cost-effective therapies, which can pressure manufacturers to justify higher prices through evidence of clinical superiority or convenience. Medicare and Medicaid policies in the U.S., coupled with private insurer negotiations, can significantly impact attainable price points.


Regulatory Factors

The regulatory pathway impacts time-to-market and pricing. Approval through the FDA’s accelerated pathways (e.g., Breakthrough Therapy, Orphan Drug) may lead to earlier commercial availability, potentially enabling premium pricing strategies due to unmet needs or expedited access.

Post-market surveillance and value-based agreements influence pricing sustainability. For example, outcomes-based pricing models are increasingly adopted to align cost with clinical benefit, especially for high-cost specialty drugs.


Historical Pricing Trends

Historically, specialty medications like biologics or advanced therapies tend to command higher prices:

  • Initial Launch Prices: Range from $20,000 to over $100,000 annually, depending on therapeutic class and indication.
  • Price Adjustments: Average annual increases in drug prices have hovered around 3-7% in recent years, influenced by inflation, manufacturing costs, and market competition.

Forecasting prices for NDC 60429-0048 must consider these historical trends alongside current market factors. If the drug is a biologic, initial list prices are likely high but could decrease as biosimilars enter the market.


Price Projection Framework

Short-term (1-2 years)

  • Under Patent Protection: Expect stable or slightly increasing list prices, with initial annual increases of 3-5%. Launch price could be between $30,000 and $80,000 per treatment course, depending on indication.
  • Reimbursement Trends: Negotiations with payers may moderate effective prices, but manufacturer discounts and rebates can suppress list prices in practice.

Medium-term (3-5 years)

  • Patent Expiry & Biosimilar Entry: Price reductions of 20-40% are typical post-patent loss, depending on biosimilar competition.
  • Market Uptake: Differentiation and demonstration of superior efficacy could enable sustained premium pricing.

Long-term (>5 years)

  • Market Saturation & Competition: Price erosion could continue, especially if biosimilars capture significant market share.
  • Market Dynamics: Regulatory changes and new therapeutic developments could further influence pricing strategies, potentially leading to lower price ceilings.

Strategic Considerations

  • Value-based Pricing: Emphasizing clinical benefits than sheer list price can optimize reimbursement.
  • Partnerships & Licensing: Collaborations for expanded indications or biosimilar development can influence future price trajectories.
  • Market Expansion: Entry into international markets with different pricing and reimbursement environments might diversify revenue streams and impact domestic pricing strategies.

Key Takeaways

  1. Market Size is Variable: Indication-specific prevalence and competition levels heavily influence potential revenue. Detailed epidemiological data is necessary for precise forecasts.
  2. Patent Status Drives Prices: Exclusive rights enable premium pricing, with inevitable declines post-exclusivity.
  3. Reimbursement Policies are Critical: Effective engagement with payers is essential to realize projected prices.
  4. Biosimilar Competition Will Impact Pricing: Entry of biosimilars can reduce prices by 20-40% over 3-5 years.
  5. Pricing Trends Remain Tied to Clinical Value: Demonstrated added benefit supports premium prices and market share.

FAQs

Q1: What is the typical lifespan of patent exclusivity for biologic drugs like NDC 60429-0048?
A1: Biologics generally enjoy 12 years of exclusivity in the U.S., with some variations depending on regulatory and legal factors ([1]).

Q2: How do biosimilar entries influence the pricing of original biologics?
A2: Biosimilar competition typically prompts discounts ranging from 20% to 40%, leading to significant price reductions within 3–5 years of biosimilar approval ([2]).

Q3: What strategies can manufacturers adopt to maintain pricing power?
A3: Emphasizing clinical superiority, line extensions, expanding indications, and engaging in value-based pricing agreements enhance pricing resilience.

Q4: How do reimbursement policies impact net realization of drug prices?
A4: Reimbursement negotiations, formulary placements, and coverage limitations can reduce net prices below list prices, making payor relationships vital.

Q5: What are the key factors influencing long-term price declines?
A5: Patent expiration, biosimilar introduction, market penetration, and evolving regulatory landscapes collectively precipitate sustained price decreases.


Conclusion

The market for NDC 60429-0048 remains promising, especially if pioneering novel therapeutic benefits and securing patent protections. Price stability hinges on maintaining exclusivity, demonstrating clinical value, and strategic engagement with payers. As biosimilars and generics enter the scene, players must adapt to a landscape where costs decrease, but opportunities for innovation-driven premium pricing persist through differentiation and expanded indications. Forward-looking stakeholders should focus on early market positioning, securing regulatory advantages, and establishing value-based frameworks to optimize revenue potential.


References

  1. U.S. Food and Drug Administration (FDA). “Biologics Price Competition and Innovation Act (BPCIA).”
  2. IQVIA Institute. “The Impact of Biosimilars on Price, Spending, and Access.”

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