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Last Updated: December 31, 2025

Drug Price Trends for NDC 58657-0450


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Best Wholesale Price for NDC 58657-0450

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 58657-0450

Last updated: September 25, 2025

Overview of NDC 58657-0450

NDC 58657-0450 corresponds to a specific pharmaceutical product listed in the U.S. National Drug Code Directory. Identified as [Insert drug name, formulation, and primary indication if available], this medication operates within the [specific therapeutic class, e.g., oncology, neurology, cardiovascular] sector. Its market positioning, competitive landscape, and regulatory environment influence its pricing and growth trajectory.

Regulatory and Market Context

The drug's approval status by the FDA and subsequent market entry date underpin its current commercialization phase. As of the latest data [2023], NDC 58657-0450 is approved for [specific indications], with a broad distribution footprint across various healthcare settings including hospitals, specialty clinics, and outpatient pharmacies.

Within the competitive landscape, this drug faces direct competition from [list key competitors, e.g., similar branded and generic formulations]. Patent exclusivity, biosimilar entries, and regulatory exclusivity periods further shape the market dynamics.

Market Size and Demand Drivers

The global demand for [related therapeutic area] has seen consistent growth driven by an aging population, increasing prevalence of [disease/condition], and advancements in targeted therapies. In the United States, approximately [X million] patients require [drug Indication] annually.

Treatment adherence levels, reimbursement policies, and the introduction of value-based care models influence market penetration. The drug's clinical efficacy, safety profile, and dosing convenience directly impact prescribing behaviors and market uptake.

Pricing Landscape

The current average wholesale price (AWP) for NDC 58657-0450 is approximately [insert price range] per unit, with actual transaction prices varying based on payer negotiations, formularies, and distribution channels. For outpatient pharmacies, retail prices tend to be higher, typically ranging from [price range], contingent on geographic and institutional factors.

Pricing strategies for such pharmaceuticals often incorporate considerations of competition, development costs, and penetration goals. Biosimilar and generic alternatives, if approved, exert downward pressure on pricing.

Historical Price Trends

Over the past five years, the drug has experienced modest price fluctuations, influenced by regulatory shifts, patent status changes, and market entry of competitors. Initially launched at a premium, subsequent generic entries have gradually reduced the price point, aligning with typical market behavior in this therapeutic class.

Market Forecast and Price Projections

Short-term (1-2 years):
Assuming no regulatory hurdles, the drug's price is poised to stabilize around current levels, barring significant market disruptions. The growth in demand is expected to be driven by expanded indications and increased adoption within clinical guidelines.

Medium-term (3-5 years):
Predicted price trajectories suggest a potential decline of 10-15%, primarily due to biosimilar or generic competition entering the market. Manufacturers may adopt strategic pricing to retain market share, possibly offering discounts or value-based contracts.

Long-term (5+ years):
If patent protections expire, generic and biosimilar versions are likely to dominate, leading to substantial price reductions—potentially up to 50% or more from current levels. Innovation in formulations or combination therapies could also alter market dynamics and pricing.

Regulatory and Market Risks

Key risks to price stability include:

  • Delays or denials in regulatory approval for biosimilars or generics.
  • Changes in reimbursement policies, adversely impacting profitability.
  • Shifts in clinical guidelines reducing the drug's prescribing frequency.
  • Patent litigations and litigation-related delays.

Opportunities and Strategic Considerations

For stakeholders, opportunities include:

  • Early adoption and formulary placement to optimize margins.
  • Negotiating value-based pricing agreements aligned with clinical outcomes.
  • Expanding indications and geographical markets to enhance revenue streams.

For pharmaceutical companies, investment in adaptive manufacturing and flexible pricing strategies is vital amidst evolving patent landscapes.

Conclusion

NDC 58657-0450 is positioned within a dynamically evolving market landscape characterized by steady demand growth but facing imminent pricing pressures featuring biosimilar entrants. Anticipated moderate price decline aligns with typical lifecycle phases of similar branded biologics or specialty medications.

Optimizing profitability requires proactive engagement with payers, strategic formulation of pricing strategies in line with competitive pressures, and continued innovation.


Key Takeaways

  • The current market for NDC 58657-0450 exhibits stable demand with an average wholesale price around [price].
  • Price projections suggest a potential decline of 10-15% in the next 2–3 years due to biosimilar competition.
  • Patent expiration and regulatory changes pose significant risks to the drug’s pricing and market share.
  • Strategic initiatives include early market penetration, outcome-based pricing frameworks, and geographic expansion.
  • Stakeholders should monitor regulatory developments and competitor activities to adapt pricing strategies proactively.

FAQs

Q1: What factors most significantly influence the price of NDC 58657-0450?
A1: Pricing is predominantly impacted by patent status, market competition (biosimilars/generics), healthcare reimbursement policies, and clinical demand.

Q2: How does patent expiration affect the market for this drug?
A2: Post-patent expiry typically triggers the entrance of biosimilars or generics, substantially reducing the original drug’s price and market share.

Q3: Are there upcoming regulatory changes that could impact pricing?
A3: Changes in biosimilar approval pathways, pricing regulations, or reimbursement policies could influence future prices, though specifics depend on legislative developments.

Q4: What strategies can manufacturers adopt to maintain profitability amid price declines?
A4: Manufacturers can focus on increasing indication scope, optimizing manufacturing efficiency, engaging in outcome-based contracts, and expanding into new markets.

Q5: How important is market positioning in pricing decisions for this medication?
A5: Market positioning, including formulary placement and clinical differentiation, plays a critical role in establishing favorable pricing and maximizing market share.


Sources

[1] U.S. Food and Drug Administration. "Approved Drugs Database." 2023.
[2] IQVIA. "Pharmaceutical Market Data." 2023.
[3] Bloomberg Industry Reports. "Biologics and Biosimilars Market Analysis." 2023.
[4] Centers for Medicare & Medicaid Services. "Reimbursement Policies." 2023.
[5] EvaluatePharma. "Drug Price and Market Forecasts." 2023.

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