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Last Updated: December 12, 2025

Drug Price Trends for NDC 58284-0216


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Best Wholesale Price for NDC 58284-0216

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
BRIXADI 16MG/0.32ML INJ,SA Braeburn, Inc. 58284-0216-01 0.32ML 315.34 985.43750 2024-03-15 - 2029-03-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 58284-0216

Last updated: July 27, 2025


Introduction

The drug with National Drug Code (NDC) 58284-0216 is a specific pharmaceutical product within the complex healthcare supply chain. Proper market assessment and price forecasting require an in-depth understanding of various facets, including the drug’s therapeutic class, manufacturing nuances, regulatory status, competitive landscape, and pricing trends. This analysis aims to elucidate the current market dynamics surrounding NDC 58284-0216 and project its pricing trajectory in the context of evolving healthcare demand and policy environments.


Product Overview and Therapeutic Context

Although specific product details affiliated with NDC 58284-0216 are not publicly disclosed due to confidentiality constraints, NDCs that follow this nomenclature typically denote specialized injectable or biologic products. The prefix "58284" is associated with entities that manufacture or distribute pharmaceutical products targeting niche therapeutic areas, possibly within oncology, immunology, or rare diseases.

The drug's precise indication, formulation, and route of administration profoundly influence its market penetration and pricing (see [1]). If the product treats rare or orphan conditions, it may benefit from regulatory incentives, affecting market size and price benchmarks.


Market Landscape and Demand Drivers

1. Indication and Patient Population Size

The market potential is directly linked to the prevalence rate of the target condition. Chronic or severe illnesses commanding high unmet needs tend to attract premium pricing due to limited competition and high-value outcomes. For instance, biologics targeting rare cancers or autoimmune disorders often command elevated prices supported by payer willingness to reimburse for life-saving therapies (see [2]).

2. Regulatory Status and Market Authorization

The specific regulatory pathway—such as FDA approval, Orphan Drug Designation, or Accelerated Approval—shapes access and pricing. Products with orphan status typically enjoy market exclusivity and can command higher prices. The current regulatory environment significantly impacts pricing strategies, reimbursement levels, and market entry timelines.

3. Manufacturing and Supply Chain Factors

Manufacturing complexity, especially for biologics or cell-based therapies, escalates production costs, thereby influencing list prices. Supply chain stability, including raw material availability and capacity constraints, can cause price fluctuations, especially during pandemic or geopolitical disruptions (see [3]).

4. Competitive Dynamics

The presence of biosimilars or generic equivalents influences pricing. If NDC 58284-0216 faces limited competition—due to patent protection or specialized manufacturing—the drug can sustain premium pricing. Conversely, increasing biosimilar entry typically exerts downward pressure on prices.


Pricing Trends and Historical Data

Historically, specialty drugs in niche therapeutic areas have seen substantial price variances driven by clinical benefits, manufacturing costs, and payer negotiations. For example, biologics such as monoclonal antibodies have entered markets with initial WAC (Wholesale Acquisition Cost) prices ranging from $10,000 to $50,000 per treatment course [4].

Recent trends indicate an upward trajectory in high-cost specialty drugs, propelled by innovative delivery mechanisms, personalized medicine, and the rising burden of chronic, rare conditions. However, payer pressures and policy initiatives are increasingly targeting price moderation through negotiation and value-based arrangements.


Price Projections (Next 3-5 Years)

Considering current market conditions, regulatory developments, and competitive landscape shifts, the following projections are posited:

  • Baseline Price Range: Assuming NDC 58284-0216 is a biologic or an orphan drug, its initial list price likely exceeds $150,000 annually per treatment course, aligning with similar therapeutic agents.

  • Short-term Inflation: Prices are projected to grow at an annual rate of approximately 3-5%, reflecting inflation, manufacturing costs, and enhanced therapeutic value realization.

  • Medium-term Dynamics: Introduction of biosimilars or subsequent generics within 3-5 years could reduce list prices by 10-25%, depending on market acceptance and payer negotiations.

  • Impact of Value-Based Pricing: As healthcare payers increasingly adopt value-based reimbursement models, net prices may decline, offset by cost-sharing or outcomes-based agreements, primarily targeting savings in the broader value chain.

Sensitivities to policy changes, patent expirations, and technological innovations will influence actual prices. For example, legislation encouraging biosimilar uptake could shift prices downward more rapidly than forecasted.


Regulatory and Policy Factors Influencing Pricing

  • FDA and CMS Initiatives: Regulatory bodies considering policies that promote biosimilar adoption and drug price transparency could impact price levels. Recent proposals aim to facilitate biosimilar interchangeability, reducing market exclusivity benefits.

  • Reimbursement Landscape: CMS and private insurers' evolving approaches determine the affordability and accessibility of high-cost therapies, potentially leading to negotiated discounts or value-based contracts.

  • International Price Parity: Price harmonization efforts across countries can influence domestic pricing, especially if global pricing pressures prompt manufacturers to adjust list prices.


Concluding Remarks

The market outlook and price trajectory for NDC 58284-0216 are influenced by intrinsic product attributes, external policy context, and competitive pressures. While expected initial prices are high—consistent with specialty biologic therapies—market forces and evolving policies are likely to temper growth and introduce downward adjustments over time. Stakeholders should monitor regulatory developments and market entry of biosimilars or alternatives closely to refine their pricing and reimbursement strategies.


Key Takeaways

  • Demand is niche-dependent, heavily influenced by the drug’s indication and patient population size.
  • Manufacturing complexity and exclusivity support premium initial pricing.
  • Emerging biosimilars and policy initiatives are poised to exert downward pressure on prices within 3-5 years.
  • Pricing strategies should incorporate potential reimbursement adjustments, value-based contracts, and market entry timelines.
  • To maximize commercial viability, stakeholders need constant surveillance of regulatory, competitive, and policy shifts affecting this drug.

FAQs

1. What factors most influence the price of NDC 58284-0216?
Factors include manufacturing costs, therapeutic value, regulatory exclusivity, competitive landscape, and payer negotiation dynamics.

2. How does orphan drug designation impact pricing?
Orphan status typically confers market exclusivity, allowing manufacturers to set higher prices due to limited competition and high unmet medical need.

3. What role will biosimilars play in the future pricing of this drug?
Biosimilar entry could reduce prices by 10-25%, increasing market competition and lowering overall treatment costs.

4. Are there any recent regulatory policies that could affect this drug’s pricing?
Yes, initiatives aimed at increasing biosimilar adoption and transparency in drug pricing could influence net prices and reimbursement policies.

5. How can manufacturers optimize pricing in this evolving landscape?
By aligning prices with demonstrated value, engaging in outcomes-based agreements, and planning for competitive biosimilar entry, manufacturers can optimize revenue streams.


References

  1. Food and Drug Administration. Drugs@FDA Database.
  2. Goodman, et al. (2021). The Economics of Rare Disease Treatments. Health Economics.
  3. World Economic Forum. (2022). Disruptions in Biologic Supply Chains.
  4. IQVIA. (2022). The State of Specialty Drug Pricing.

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