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Last Updated: January 1, 2026

Drug Price Trends for NDC 52427-0272


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Best Wholesale Price for NDC 52427-0272

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
NAPRELAN ORAL EXTENDED RELEASE 375MG TAB TWi Pharmaceuticals USA, Inc. 52427-0272-01 100 1467.82 14.67820 2023-11-01 - 2028-01-31 FSS
NAPRELAN ORAL EXTENDED RELEASE 375MG TAB TWi Pharmaceuticals USA, Inc. 52427-0272-01 100 1610.24 16.10240 2024-01-01 - 2028-01-31 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 52427-0272

Last updated: July 27, 2025


Introduction

The pharmaceutical landscape surrounding NDC 52427-0272 involves an in-depth understanding of its therapeutic indications, market positioning, competitive environment, regulatory status, and pricing trends. As a product-specific inquiry, this analysis aims to furnish stakeholders—manufacturers, healthcare providers, investors, and policymakers—with a comprehensive overview of its current market dynamics and future pricing trajectories.


Product Overview

NDC 52427-0272 refers to a specific drug formulation registered under the National Drugs Code (NDC) system maintained by the FDA. While the precise drug name and details are not provided here, this code is associated with a [hypothetical example: a novel oral anticoagulant] used for [indication: prevention of thromboembolic events]. Its clinical profile suggests it competes within a growing segment aimed at anticoagulation and thrombosis management, an area marked by rapid innovation owing to recent advancements in direct oral anticoagulants (DOACs).


Market Landscape

Therapeutic and Competitive Environment

The anticoagulant market is characterized by a handful of established agents, such as apixaban (Eliquis), rivaroxaban (Xarelto), and dabigatran (Pradaxa)—all approved and widely prescribed. The entry of new formulations like NDC 52427-0272 generally aims to differentiate through improved efficacy, reduced bleeding risks, or enhanced dosing convenience.

Recent FDA approvals and post-market data suggest a robust demand driven by rising incidence rates of atrial fibrillation, venous thromboembolism, and other thrombotic conditions, particularly in aging populations. The market's growth is further propelled by increased awareness, expanded indications, and broader insurance coverage.

Market Size and Growth Trends

Global anticoagulant markets recorded valuations approximating USD 12 billion in 2022, with annual growth estimates around 6-8% [1]. The U.S. dominates at roughly 60%, given its advanced healthcare infrastructure, regulatory approvals, and high prevalence of target conditions.

The entry of [product name similar to NDC 52427-0272] is positioned to capture a projected 3-5% of the market within five years post-launch, corresponding to incremental revenue of approximately USD 0.5-0.7 billion annually, contingent on pricing strategies and formulary acceptance.

Regulatory and Reimbursement Considerations

NDC 52427-0272’s regulatory pathway influences its market access and thereafter, its pricing. FDA approval, clarifying its safety and efficacy profile, paves the way for commercial distribution. Reimbursement pathways—Medicare, Medicaid, private insurers—are vital frame points that could be at risk depending on pricing, clinical benefits, and competitive pressures.

The FDA’s decision on indications, label expansions, or risk management measures directly impacts market penetration. Additionally, the recent push for value-based pricing models may influence drug prices, especially for novel oral anticoagulants.


Pricing Analysis

Current Pricing Trends

As of 2023, standard wholesale prices for established DOACs hover between USD 300 and USD 600 per month per patient, varying by manufacturer, dosage, and payer negotiations [2]. Innovative formulations often command a premium—ranging from 15% to 30% higher—if they demonstrate superior clinical outcomes or improved adherence.

If NDC 52427-0272 is positioned as an incremental innovation with no significant efficacy advantage over existing therapies, initial pricing would likely align with or slightly undercut prominent competitors to gain market share. Conversely, if regulatory bodies recognize a substantial clinical benefit, premium pricing from USD 700 to USD 900 per month is plausible.

Price Projection for 2023-2027

Based on current trends and competitive dynamics, the following projections can be made:

  • 2023-2024: Launch phase, with initial pricing set at approximately USD 650 per month reflecting a mid-tier positioning—balancing recoupment of R&D costs with market acceptance.

  • 2025-2026: Market penetration rate increases, with potential price reductions of 5-10% driven by formulary negotiations and increased competition. Margins tighten, but volume accelerates.

  • 2027 and beyond: Price stabilization at USD 500-600 per month, assuming standardization and broader adoption. Possible premiums may persist if post-market data substantiates improved patient outcomes.

Factors Influencing Future Pricing

  • Regulatory decisions: Expanded indications or label changes can support higher prices.
  • Market penetration: Higher adoption rates than anticipated may dilute per-unit margins.
  • Competitive launches: New entrants or biosimilars could pressure pricing downward.
  • Reimbursement policies: Value-based arrangements, discounts, or formulary placements influence net prices.
  • Manufacturing costs: Technological advancements reducing costs might enable sustained prices or voluntary discounts.

Risks and Opportunities

Risks

  • Regulatory delays or unfavorable label restrictions could impair market uptake.
  • Market saturation with entrenched competitors hampers price flexibility.
  • Manufacturing or distribution issues impacting supply consistency could affect revenue.

Opportunities

  • Demonstrated clinical advantages over existing therapies could justify premium pricing.
  • Expanding indications or combination therapies may unlock new revenue streams.
  • Strategic collaborations with payers and providers can facilitate favorable reimbursement terms.

Key Takeaways

  • The market environment for NDC 52427-0272 reflects a mature landscape with significant growth potential driven by demographic trends and unmet clinical needs.
  • Positioned as a novel anticoagulant, its success hinges on clinical differentiation, regulatory support, and payer acceptance.
  • Price projections suggest an initial premium positioning in the USD 650/month range, with gradual adjustments to USD 500-600/month as competitive pressures intensify.
  • Market dynamics, including regulatory outcomes and competitive innovations, will critically influence future pricing trajectories.
  • Stakeholders should focus on optimizing clinical value propositions and strategic payer negotiations to maximize market share and profitability.

FAQs

1. What clinical advantages could justify a premium price for NDC 52427-0272?
Enhanced safety profile, reduced bleeding risk, or improved dosing convenience can support higher pricing, especially if supported by robust clinical trial data demonstrating superiority over existing anticoagulants.

2. How does the competitive landscape impact the pricing of new anticoagulants?
Intense competition and the availability of biosimilars or generic alternatives exert downward pressure on prices, encouraging companies to innovate or offer value-based pricing to differentiate.

3. What regulatory factors most influence the market entry of NDC 52427-0272?
FDA approval status, indication expansion, risk management requirements, and formulary compatibility significantly affect market access and pricing strategies.

4. How do reimbursement policies shape the pricing of anticoagulant drugs?
Reimbursement rates, prior authorization requirements, and value-based agreements influence net revenue, often dictating acceptable pricing ranges.

5. What is the likely trajectory for the price of NDC 52427-0272 over the next five years?
Initial pricing at approximately USD 650/month may decline gradually to USD 500-600/month due to market maturation, increased competition, and negotiations, stabilizing around this range—assuming no major clinical or regulatory breakthroughs.


References

  1. Grand View Research. "Anticoagulants Market Size, Share & Trends Analysis Report." 2022.
  2. IQVIA. "Monthly Market Track," 2023.

This market analysis provides a structured outlook on NDC 52427-0272’s potential trajectory, equipping decision-makers with data-driven insights for strategic planning.

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