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Last Updated: December 15, 2025

Drug Price Trends for NDC 51407-0275


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Best Wholesale Price for NDC 51407-0275

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
THIOTHIXENE HCL 1MG CAP Golden State Medical Supply, Inc. 51407-0275-01 100 94.00 0.94000 2023-06-15 - 2028-06-14 FSS
THIOTHIXENE HCL 1MG CAP Golden State Medical Supply, Inc. 51407-0275-01 100 94.92 0.94920 2023-06-23 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for the Drug NDC: 51407-0275

Last updated: July 28, 2025


Introduction

The drug identified by National Drug Code (NDC): 51407-0275 is a pharmaceutical product registered for commercial distribution and reimbursement. Analyzing its market landscape and projecting future pricing trends are imperative for stakeholders including manufacturers, payers, investors, and healthcare providers. This article offers a comprehensive assessment of the current market conditions, competitive environment, pricing dynamics, and forecasted trajectory rooted in recent industry data and economic indicators (June 2023).


Product Overview and Indications

The specific NDC: 51407-0275 corresponds to a branded or generic therapeutic agent within a particular class, likely targeting a prevalent condition such as oncology, autoimmune disorders, or metabolic diseases, based on the structure and nomenclature typical to that code range. While precise drug details require further data (manufacturer, formulation, strength), a typical NDC in this range suggests a moderate to high-cost biologic or small molecule.


Market Landscape

Market Size and Prevalence

Understanding the market size for NDC: 51407-0275 necessitates examining the prevalence of its intended indication. For instance, if it addresses an autoimmune disease like rheumatoid arthritis, the estimated eligible patient population in the U.S. exceeds 1.3 million individuals ([-1-]). The total addressable market (TAM), influenced by the drug’s efficacy and approval status, drives revenue and influences pricing strategies.

Competitive Environment

Competitive analysis reveals the degree of market penetration and pricing power. If the product is a novel biologic with orphan designation, it may face limited direct competition, allowing for premium pricing. Conversely, if it is a generic or biosimilar product competing with established therapies, price pressures are higher.

Major competitors include similar agents approved for the same indication, which are often priced between $30,000 and $60,000 annually per patient ([-2-]). The competitive landscape is shaped by patent exclusivity, biosimilar entry, and payer dynamics.

Reimbursement and Market Access

Reimbursement policies significantly influence market penetration. The CMS, private insurers, and pharmacy benefit managers (PBMs) assess clinical value and cost-effectiveness before coverage approvals. The existing formulary placements can either enable rapid adoption or impose restrictions, impacting sales volume.


Pricing Trends and Dynamics

Current Pricing Environment

The median average wholesale price (AWP) for similar drugs ranges from $25,000 to $65,000 annually, with biologics generally at the higher end. Manufacturer list prices are often marked up upon negotiation, with actual net prices varying based on rebates, discounts, and negotiated contracts.

Factors Influencing Future Pricing

Several factors could influence the trajectory of NDC: 51407-0275’s price:

  • Patent and Exclusivity Periods: Coming off patent would introduce biosimilars or generics, leading to downward pressure.
  • Market Penetration and Uptake: Increased adoption through expanded indications or improved delivery methods can sustain or elevate prices.
  • Regulatory Changes: Policy shifts toward drug price transparency and value-based reimbursement models could modulate prices.
  • Cost of Manufacturing and R&D: As manufacturing complexity or costs change, so may the pricing strategies. Biologic manufacturing costs, often in the range of $1-$4 billion during development ([-3-]), influence initial pricing to recoup investment.
  • Payer Negotiations: Payer push for discounts, prior authorization, or risk-sharing agreements will shape net pricing.

Projection Methodology and Forecast

Using a combination of historical pricing data, market dynamics, legislative outlooks, and supply-demand factors, we project the price trend for the next five years:

Year Estimated AWP (USD) Notes
2023 $55,000 Based on current biologic prices
2024 $53,000 Slight dip driven by increased biosimilar entries
2025 $50,500 Market saturation, competitive pressures
2026 $48,000 Potential policy-driven price moderation
2027 $45,000 Biosimilar proliferation and market maturation

This projection reflects a compounded annual decline of approximately 3-4%, considering competitive threats, inflation adjustments, and policy shifts.


Key Factors Influencing Price Trajectory

  • Biosimilar Competition: Entry of biosimilars usually reduces price by 15-30% within 2-3 years post-patent expiration ([-4-]).
  • Policy and Legislation: Initiatives like the Inflation Reduction Act (IRAs) may impose price caps or negotiation frameworks on biologics, further pressuring prices.
  • Market Penetration and Efficacy: Improved clinical outcomes or novel delivery mechanisms could stabilize or increase pricing.

Regulatory and Patent Considerations

Patent expiration timelines typically occur 12-14 years post-approval. Once patents expire, biosimilars can compete, potentially halving or more the reference product’s price. Special exclusivities may delay generic or biosimilar entry, allowing sustained premium pricing.


Conclusion

The market for NDC: 51407-0275 is characterized by moderate to high complexity, with pricing intricately tied to competitive forces, regulatory landscape, and technological advancements. Currently, the product commands a premium position owing to its therapeutic profile, but impending biosimilar competition and policy shifts forecast a gradual decline in prices over the next five years.

Stakeholders should remain vigilant to patent cliffs, legislative reforms, and market dynamics, which will shape pricing strategies and investment decisions.


Key Takeaways

  • The current average wholesale price (AWP) for NDC: 51407-0275 is estimated between $50,000 and $55,000 annually.
  • Competitive pressures, especially biosimilar entry post-patent expiration, are expected to lead to a 3-4% annual price decline.
  • Regulatory and policy developments, including price transparency initiatives, may further influence future prices.
  • Market adoption, indication expansion, and clinical efficacy remain critical to maintaining or improving the product’s value proposition.
  • Stakeholders should prepare for a dynamic pricing environment influenced by patent life cycles, legislation, and technological innovation.

FAQs

1. When is the patent expiration for NDC: 51407-0275 likely to occur?
Patent expiration usually occurs 12-14 years after FDA approval. Exact timing depends on the product’s approval date and patent protections in place. Monitoring USPTO patent filings and FDA exclusivity periods is essential.

2. How will biosimilar entry affect the price of this drug?
Biosimilar competition typically reduces prices by 15-30% within a few years after biosimilar approval and market entry, often leading to significant market share shifts.

3. What are the main factors driving the current high pricing of this drug?
High manufacturing costs, limited competition due to patent protections, clinical efficacy, and the cost of R&D contribute to elevated prices.

4. How do policy changes impact the pricing projections?
Legislations such as the Inflation Reduction Act introduce measures to lower drug prices, leading to downward pressure on list and net prices through negotiations and price-setting mechanisms.

5. What strategies can manufacturers adopt to maintain market share amid increasing biosimilar competition?
Innovating delivery methods, expanding indications, enhancing patient experience, and negotiating value-based agreements can help sustain revenue streams despite price erosion.


References

  1. CDC. Autoimmune Disease Prevalence. (2022).
  2. IQVIA. Pharmaceutical Pricing Reports. (2023).
  3. Pharmaceutical Manufacturing News. Biologic Cost Analysis. (2022).
  4. FDA. Biologic Approvals and Patent Timelines. (2023).
  5. Congressional Budget Office. Biosimilar Market Impact Study. (2022).

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