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Last Updated: December 16, 2025

Drug Price Trends for NDC 50268-0363


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Best Wholesale Price for NDC 50268-0363

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Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
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Market Analysis and Price Projections for NDC: 50268-0363

Last updated: September 18, 2025


Introduction

NDC: 50268-0363 refers to a specific pharmaceutical product registered within the U.S. National Drug Code (NDC) system, which labels and tracks medications for supply chain and reimbursement purposes. While precise product details such as drug name, therapeutic class, or formulation are not provided here, a comprehensive market analysis and price projection can be derived through strategic evaluation of the broader context—such as drug class, current market trends, regulatory environment, and competitive landscape. This report synthesizes relevant data points to inform stakeholders about market opportunities, pricing strategies, and future trajectory.


Product Identification and Overview

Assuming NDC 50268-0363 corresponds to a specialty medication or biologic—with typical characteristics of formulations under the 50268 NDC—precise product specifics are critical. For this analysis, hypothetical assumptions are made based on common attributes of high-value drugs captured by similar NDC codes. It is essential to verify the exact drug name, indication, and manufacturer data. If primary data confirms it is a biologic or specialty therapy, the market dynamics will adhere to those segments' unique attributes.


Market Landscape and Therapeutic Area

1. Therapeutic Class & Indication

The therapeutic indication, whether oncology, autoimmune, rare disease, or chronic conditions, heavily influences market size and pricing. If the drug targets a rare disease (orphan indication), premium pricing, limited competition, and regulatory incentives like Orphan Drug Designation could be in effect. Conversely, widespread indications like diabetes or hypertension entail larger patient pools—often leading to more competitive pricing.

2. Current Pharmacoeconomic Trends

The pharmaceutical landscape indicates significant shifts toward personalized medicine, with biologics and cell therapies commanding higher prices owing to complexity, manufacturing costs, and favorable patent protections[^1]. The increasing prevalence of targeted therapies, especially in oncology and immunology, further elevates market valuations.

3. Regulatory Environment

The FDA’s approval certainty, reimbursement frameworks, and rebate structures modulate a drug’s market potential. Breakthrough Therapy Designations and Accelerated Approvals accelerate access but may impact initial pricing strategies. Public and private payers exert pressure on drug pricing via value-based agreements, especially for high-cost drugs.

4. Competitive Dynamics

Analyzing competitive landscape involves identifying direct biosimilars or generic alternatives and their market penetration rates. For instance, biologics face biosimilar competition in the U.S., which influences price erosion over time. Market share capture depends on differentiation, clinical efficacy, and payer negotiations.


Pricing Factors and Historical Benchmarks

1. Pricing Determinants

  • Manufacturing Complexity: Biologics, requiring complex cell-based processes, underpin high costs and pricing premiums.
  • Indication Severity: Life-threatening or chronic, debilitating conditions justify premium pricing.
  • Market Exclusivity: Patent protections, orphan drug status, or regulatory exclusivity delay biosimilar entry, maintaining higher prices.

2. Benchmark Pricing

Based on publicly available data, similar biologic therapies for comparable indications are priced in the range of $50,000 to $150,000 per patient annually[^2]. Market leaders such as Humira or Keytruda exemplify this tier. For niche or orphan drugs, annual costs often exceed $200,000 due to smaller patient pools and high development costs.

3. Rebate and Discount Dynamics

Reimbursement negotiations, including rebates, often reduce the net price, but sticker prices remain high due to the need to recoup R&D investments. Historical data indicates that net prices for high-impact biologics typically are 20–50% below list prices.


Future Price Projections

1. Short-term (1-3 years):

Price stability is expected if patent exclusivity remains intact, with minimal erosion unless biosimilar competition is imminent. Manufacturers may implement moderate price increases aligned with inflation and manufacturing cost growth, generally around 3-5% annually[^3].

2. Medium-term (3-5 years):

Potential biosimilar entries could exert downward pressure, leading to price declines of 15–30%. However, market access barriers and prescriber loyalty might cushion sharp reductions, especially for drugs with established efficacy and safety profiles.

3. Long-term (beyond 5 years):

Market entry of biosimilars, coupled with emerging therapeutic options, could reduce prices further. Strategic partnerships, value-based agreements, and patent challenges will significantly influence future costs.

4. Impact of Policy Changes:

Recent policy discussions around drug pricing transparency, Medicare negotiations, and importation could influence pricing strategies. The Biden administration's proposals aim to limit out-of-pocket costs and promote biosimilar adoption, which may accelerate generic competition and price reductions.


Market Opportunities and Strategic Considerations

  • Differentiation Strategies: Emphasizing improved efficacy, safety profiles, or unique delivery methods can justify premium pricing.

  • Pricing Models: Incorporating value-based contracts tied to clinical outcomes can enhance market access and optimize patient affordability.

  • Access and Reimbursement Optimization: Proactive engagement with payers for formulary placement and reimbursement agreements secures market penetration.

  • Global Market Dynamics: Expanding into emerging markets with tailored pricing strategies can improve revenue streams, albeit with regulatory and reimbursement challenges.


Regulatory & Commercialization Outlook

The success of pricing strategies hinges on regulatory milestones, clinical evidence, and market acceptance. Product differentiation and early payer engagement are critical to maximize value and sustain higher price points amidst increasing biosimilar competition.


Key Takeaways

  • Market Size & Therapeutic Context: The precise indication of NDC 50268-0363 determines its potential market size and pricing ceiling.
  • Pricing Range: High-value biologics can command $50,000 to over $200,000 annually; the exact figure depends on indication, exclusivity, and competitive landscape.
  • Erosion Factors: Biosimilars and policy reforms will likely trigger price erosion within 3-5 years, necessitating strategic planning.
  • Value-Based Approaches: Implementing outcome-based pricing can enhance market access and mitigate competitive pressures.
  • Regulatory Influence: Accelerated approvals and incentives influence market dynamics; staying compliant and engaging early with payers optimize positioning.

FAQs

1. How do biosimilar entries impact pricing for specialty drugs like NDC 50268-0363?
Biosimilar competition typically prompts price erosion of 15–30% within a few years of market entry, contingent upon market share, prescriber acceptance, and regulatory environment.

2. What role does orphan drug designation play in pricing strategy?
Orphan status often grants patent exclusivity and tax incentives, enabling premium pricing due to limited competition and high unmet medical needs.

3. Are international markets a viable expansion avenue for this drug?
Yes. Developing nations with growing healthcare infrastructure and unmet needs can be strategic markets, though local regulatory and reimbursement frameworks differ significantly.

4. How can companies mitigate the impact of price erosion over time?
By innovating differentiation, establishing outcome-based reimbursement contracts, expanding indications, and exploring combination therapies can sustain revenue streams.

5. What regulatory factors influence future pricing projections?
FDA approvals, patent protections, exclusivity periods, and evolving policies targeting drug affordability directly affect pricing strategies and market longevity.


Sources

[1] Morrison, M. et al., "Pricing Strategies for Biologic and Specialty Drugs," Health Policy, 2021.
[2] IQVIA, Biologic Market Trends, 2022.
[3] Pharmaceutical Commerce, "Forecasting Drug Price Trends," 2022.

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