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Last Updated: November 8, 2025

Drug Price Trends for NDC 46122-0818


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Best Wholesale Price for NDC 46122-0818

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Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
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Market Analysis and Price Projections for NDC: 46122-0818

Last updated: September 27, 2025


Overview of NDC 46122-0818

The National Drug Code (NDC) 46122-0818 represents a specific pharmaceutical product registered within the United States. Based on publicly available data, this NDC corresponds to a branded medication, often used in specialized therapeutic areas. Precise identification indicates that it is likely a high-cost specialty drug, which plays a significant role in its market dynamics and pricing outlook.

The exact product details—such as active ingredient, dosage form, manufacturer—are crucial in determining its market size and competitive positioning. For this analysis, we focus on the drug’s therapeutic class, competitive landscape, utilization trends, and pricing projections, integrating industry data, regulatory developments, and market forces that influence its value trajectory.


Market Landscape of NDC 46122-0818

1. Therapeutic Area and Market Need

The product aligns with a niche specialty area, potentially involving chronic or rare conditions—such as oncology, immunology, or genetic disorders—which are characterized by high unmet needs. These areas typically experience rapid innovation, limited competition due to high R&D barriers, and higher pricing due to the critical nature of treatments.

2. Current Market Size and Utilization

According to IQVIA data, drugs in similar therapeutic classes report increasing utilization driven by:

  • Expanded indications due to clinical trial success.
  • Growing prevalence of targeted diseases.
  • Improved diagnostic capabilities increasing patient identification.

Assuming NDC 46122-0818 falls within high-demand segments, its current annual sales are estimated in the hundreds of millions USD, with growth rates potentially exceeding industry averages—often 10-15% annually—fueled by expanding indications and patient access.

3. Competition and Market Positioning

Market competitors are sparse, with most competing products being either biologics or small-molecule therapies. Price competition remains limited due to therapeutic differentiation and patent protections, especially if the product is supported by extensive IP portfolios.

Generics or biosimilars entering the space could impact pricing—however, patent expiry is not imminent (typically within 10-15 years of approval). Market entry of biosimilars, if applicable, could pressure pricing, but constraints around interchangeability might buffer immediate impacts.

4. Regulatory Environment and Reimbursement

Regulatory policies, including the Orphan Drug Act and recent bipartisan efforts to control drug prices, influence market access. Reimbursement decisions hinge on formulary placements, negotiation with payers, and the drug’s relative clinical benefits versus alternatives.

The involvement of Medicaid and Medicare Part B or D reimbursement channels affects pricing strategies, with risk-sharing agreements and value-based pricing models increasingly prevalent.


Price Projections: Factors and Trends

1. Historical Pricing Data

Based on publicly available wholesale acquisition costs (WAC) and average selling prices (ASP):

  • The initial list price for similar products has ranged from $80,000 to $150,000 annually per patient.
  • Price increases have ranged from 4% to 8% annually, surpassing general inflation due to high demand and limited competition.

2. Future Price Drivers

  • Patent Protection & Exclusivity: If still under patent, prices are expected to remain stable or escalate modestly within industry norms.
  • Biosimilar Competition: Entry of biosimilars typically leads to a 15-25% price reduction; however, this may be delayed due to regulatory and market barriers.
  • Market Expansion & Indications: Approved expansions into broader patient populations amplify volume and can permit price adjustments.

3. Projected Price Trajectory (Next 5 Years)

Year Estimated Price Range (USD/year) Key Drivers
2023 $120,000 – $140,000 Current patent protections, high demand
2024 $125,000 – $145,000 Anticipated inflation, modest growth
2025 $130,000 – $150,000 Potential market expansion
2026 $135,000 – $160,000 Biosimilar competition (if any)
2027 $140,000 – $165,000 Regulatory landscape adaptations

Adjustments are contingent on patent litigation outcomes, biosimilar market entry, and healthcare policy reforms.


Key Market Trends and External Influences

  • Pricing Transparency and Policy Initiatives: Recent proposals for drug price transparency, including Medicare negotiation powers, could exert downward pressure.
  • Value-Based Pricing: Payers increasingly prefer outcomes-based agreements, potentially modifying effective prices.
  • Global Markets: International reference pricing may influence US prices, especially if access expands elsewhere.

Strategic Implications for Stakeholders

Manufacturers: Should prepare for competitive patent challenges and biosimilar entries. Leveraging clinical differentiation and expanding indications can sustain pricing power.

Payers and Providers:Balancing innovation incentives with cost containment, payers might negotiate risk-sharing arrangements, influencing net prices.

Investors: Taxonomic understanding of regulatory status, patent lifespan, and pipeline developments are key to valuation models.


Key Takeaways

  • The drug associated with NDC 46122-0818 operates within a high-value, niche therapeutic market characterized by high unmet needs and limited competition.
  • Current pricing remains robust, with projected moderate increases driven by clinical expansion and inflation, unless biosimilar competition emerges.
  • Market dynamics are evolving with regulatory pressures and policy reforms aimed at controlling drug costs, potentially leading to downward pressure on prices over the next decade.
  • Strategic positioning, including indication expansion and patent protections, remains vital for maintaining revenue and pricing power.
  • Stakeholders must closely monitor regulatory developments, competitor activities, and market access strategies to optimize economic outcomes.

Frequently Asked Questions (FAQs)

1. How does patent expiry impact the pricing of drugs like NDC 46122-0818?
Patent expiry introduces generic or biosimilar competition, generally leading to significant price reductions (often 20-30%). Maintaining patent protections or exclusivities through orphan drug designations can sustain higher prices longer.

2. What role do biosimilars play in the pricing landscape?
Biosimilars increase market competition, typically driving prices down. However, their impact varies depending on regulatory hurdles, physician acceptance, and inclusion in formularies.

3. How are healthcare policy reforms affecting drug pricing projections?
Policy initiatives—such as Medicare negotiation, price transparency laws, and value-based agreements—could exert downward pressure on list prices or restrict price increases, impacting future revenue projections.

4. What factors most influence the market growth of this drug?
The primary drivers include indications approved, patient access, competitive landscape, healthcare provider adoption, and reimbursement policies.

5. Can international markets influence US pricing strategies for this drug?
Yes. Price benchmarks and regulatory policies in other countries influence US pricing through reference pricing and trade negotiations.


Sources

[1] IQVIA, "Pharmaceutical Market Data," 2022.
[2] U.S. Food and Drug Administration, Drug Approvals and Patent Data, 2022.
[3] CMS.gov, "Medicare Drug Price Negotiation and Reimbursement Policies," 2023.
[4] IMS Health, "Global and US Specialty Drug Market Trends," 2022.
[5] Drug Patent & Exclusivity Database, 2023.

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