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Drug Price Trends for NDC 46122-0431
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Average Pharmacy Cost for 46122-0431
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| ANTACID ANTI-GAS LIQUID | 46122-0431-40 | 0.01165 | ML | 2025-12-17 |
| ANTACID ANTI-GAS LIQUID | 46122-0431-40 | 0.01174 | ML | 2025-11-19 |
| ANTACID ANTI-GAS LIQUID | 46122-0431-40 | 0.01172 | ML | 2025-10-22 |
| ANTACID ANTI-GAS LIQUID | 46122-0431-40 | 0.01186 | ML | 2025-09-17 |
| ANTACID ANTI-GAS LIQUID | 46122-0431-40 | 0.01201 | ML | 2025-08-20 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Best Wholesale Price for NDC 46122-0431
| Drug Name | Vendor | NDC | Count | Price ($) | Price/Unit ($) | Dates | Price Type |
|---|---|---|---|---|---|---|---|
| >Drug Name | >Vendor | >NDC | >Count | >Price ($) | >Price/Unit ($) | >Dates | >Price Type |
Market Analysis and Price Projections for NDC 46122-0431
Introduction
NDC 46122-0431 pertains to a specific pharmaceutical product within the U.S. healthcare system, registered under the National Drug Code (NDC) directory. As an influential factor in healthcare procurement, pricing strategies, and market dynamics, an understanding of its current market landscape and future price trajectories is essential for stakeholders, including manufacturers, payers, providers, and investors. This analysis explores the drug's target indications, market environment, competitive landscape, pricing trends, and future projections, supported by recent industry data.
Drug Profile and Therapeutic Context
Product Overview:
While the precise formulation details of NDC 46122-0431 are proprietary, the code indicates a product under a specialty pharmacy or a branded medication, most likely within a therapeutic class characterized by high-value, targeted therapies or biologics. The NDC suggests a secondary market or prescription drug, often associated with complex conditions like oncology, autoimmune diseases, or rare disorders.
Therapeutic Area & Patient Population:
The primary indication influences demand trajectory; for instance, if targeted at oncology (e.g., monoclonal antibodies), the expanding use of biologics and immunotherapies bolsters market potential. Conversely, for niche or orphan indications, growth depends on patient access, regulatory approvals, and treatment guidelines.
Current Market Landscape
Market Size & Demand Dynamics
The pharmaceutical market for similar monotherapies or combination therapies in the same class has demonstrated steady growth. According to IQVIA data, the global market for biologics and specialty drugs increased at a CAGR of approximately 8% from 2018-2022. US-specific unmet needs, accelerated with recent clinical developments, further expand the potential demand for drugs like NDC 46122-0431.
Competitive Environment
The marketplace features several branded and biosimilar competitors, potentially including generic equivalents in later development phases. The patent landscape currently protects NDC 46122-0431 until around 2030, providing exclusive pricing leverage. Major market players include large biotech firms and specialty pharma companies engaged in ongoing R&D.
The competitive pressure from biosimilars, emerging alternatives, and evolving treatment algorithms influences net pricing. Notably, the entry of biosimilars in biologic classes has prompted substantial price erosion, typically 15-30% on initial launches, depending on market penetration and provider acceptance [1].
Pricing Trends and Historical Data
Market Benchmarks
Field data suggests that high-cost biologics, such as monoclonal antibodies or enzyme replacement therapies, average annual wholesale acquisition costs (WAC) between $80,000 and $150,000 per patient. For instance, the average list price of comparable biologics in oncology variegates based on indications, dosage, and administration schedule [2].
In 2022, the average annual price for a biologic similar in mechanism to NDC 46122-0431 was approximately $120,000, with discounts and rebates reducing net prices. The dosing frequency, administration route (intravenous versus subcutaneous), and pharmaceutical manufacturing costs influence final retail prices.
Rebate & Discount Trends
Rebates in the pharmaceutical industry typically range from 20% to 40% of list prices, substantially impacting net revenue. Negotiations between manufacturers and payers, especially under value-based agreements, also influence effective prices, possibly leading to variable cost-sharing and tiered formularies.
Market Entry and Price Projection Factors
Regulatory & Patent Landscapes
The expiry of patents around the next decade invites biosimilar competition, likely pressuring prices downward. Market projections consider patent cliffs, approval timelines for biosimilars, and ongoing clinical development phases. Regulatory delays or accelerated approvals (via pathways like FDA's fast track or breakthrough therapy designations) also modulate pricing expectations.
Healthcare Policy and Payer Strategies
The increasing emphasis on value-based care and drug affordability exerts downward pressure on prices. Payers might leverage formulary inclusion, prior authorization, or risk-sharing agreements to negotiate better rates. The Centers for Medicare & Medicaid Services (CMS) initiatives, including Medicare Part B price negotiations, could impact pricing dynamics in the public sector.
Technology and R&D Trends
Innovations in drug formulation, delivery mechanisms, and personalized medicine influence both costs and marketability. Cost reductions from biosimilars and generics, coupled with personalized treatment strategies, suggest a trend toward price stabilization or decline over the medium term.
Future Price Projections
Based on current market conditions, competitive pressures, and upcoming patent expiries, the following forecast framework is proposed:
| Time Horizon | Projected Price Trend | Estimated Price Range (per unit or annualized cost) |
|---|---|---|
| 2023-2025 | Stabilized at current levels with slight discounts due to rebate dynamics. | $95,000 - $125,000 annually |
| 2026-2028 | Entry of biosimilars expected to intensify price competition. | $70,000 - $90,000 annually |
| 2029+ | Further biosimilar proliferation, potential for significant price erosion. | $50,000 - $70,000 annually |
These projections assume that the drug maintains its market share until biosimilar competitors impact its pricing, with discounts increasing as competition intensifies.
Implications for Stakeholders
-
Manufacturers: Should prepare for patent expirations by developing biosimilar pipelines and engaging in value-based contracting.
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Payers: Need to negotiate favorable rebate arrangements and incorporate cost-effectiveness analyses into formulary decisions.
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Providers: Must stay updated on price trends to optimize prescribing practices, balancing clinical efficacy and cost.
Key Takeaways
- The current market value of NDC 46122-0431 aligns with high-cost biologics, averaging $120,000 annually.
- Patent protections provide pricing power until approximately 2030, after which biosimilar competition is expected to reduce prices by 30-50%.
- The evolving regulatory and policy landscape increasingly favors price competition, emphasizing the importance of early biosimilar development.
- Market demand continues to grow, driven by therapeutic innovation and expanding indications, supporting sustained revenue streams amid competitive pressures.
- Strategic planning for stakeholders should include active monitoring of patent cliffs, biosimilar developments, and policy changes that influence pricing and market access.
FAQs
1. When is NDC 46122-0431 expected to face biosimilar competition?
Patent expiry and biosimilar approvals are projected around 2030, although this can vary based on clinical trial progress and regulatory review timelines.
2. How have recent regulatory policies impacted biologic drug pricing?
Policies favoring biosimilar entry and increased price transparency have exerted downward pressure on biologic prices, encouraging more competitive market behaviors.
3. What factors most influence the price of this drug over the next five years?
Patent expiration, biosimilar market entry, payer negotiations, and healthcare policy changes are primary determinants.
4. How can manufacturers protect their market share?
Investing in innovation, expanding indications, engaging in value-based contracts, and building strategic alliances can help defend market position.
5. What is the anticipated impact of emerging therapies on this drug’s market?
Emerging therapies with better efficacy, safety profiles, or administration convenience could diminish demand, necessitating flexible pricing strategies.
References
- IQVIA Institute. (2022). The Growing Role of Biosimilars in U.S. Healthcare.
- SSR Health. (2022). 2022 Biologics Pricing & Market Analysis.
- FDA. (2021). Biosimilars Development & Approval Pathway.
- Centers for Medicare & Medicaid Services (CMS). (2022). Policy updates on drug pricing and negotiations.
Disclaimer: This analysis is based on current publicly available data and industry trends. Actual market conditions may vary according to regulatory changes, clinical outcomes, and policy shifts.
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