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Last Updated: January 1, 2026

Drug Price Trends for NDC 46122-0101


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Best Wholesale Price for NDC 46122-0101

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC: 46122-0101

Last updated: August 21, 2025


Introduction

The drug identified by NDC 46122-0101 pertains to a specific pharmaceutical product, likely a prescription medication within a regulated healthcare market. This report offers a comprehensive analysis of the current market dynamics, competitive landscape, pricing factors, and future price projections for this drug. The goal is to inform stakeholders—manufacturers, distributors, healthcare providers, and investors—about the economic and strategic considerations influencing this medication’s market trajectory.


Product Description and Indications

While specific details about NDC 46122-0101 require precise identification, the NDC code's structure suggests it is assigned to a branded or generic drug within the United States' FDA-regulated system. Based on typical NDC formatting, the product likely originates from a manufacturer with a 46122 labeler code.

Assumption: The product is a widely used therapeutic agent, possibly in treatment areas such as oncology, neurology, or chronic disease management, which often exhibit stable demand and competitive markets.


Market Landscape Overview

1. Therapeutic Area and Epidemiology

Understanding the underlying medical need is crucial. For example, if the drug treats a chronic condition with a high prevalence—such as hypertension, diabetes, or RA—the market potential remains robust. Globally, chronic disease treatments are projected to grow steadily, driven by aging populations and escalating healthcare access.

Estimated Market Size: Based on recent epidemiological data, the US market for similar drugs ranges from several hundred million to over a billion dollars annually, depending on the therapeutic class and approval breadth.

2. Competitive Environment

The number of branded and generic competitors significantly influences both pricing and market penetration. Market entry of generics historically leads to price reductions due to increased competition.

  • Branded versions typically command premiums, especially before patent expiry or exclusivity periods lapse.
  • Generics introduce downward price pressures, with recent trends showing rapid uptake post patent expiration.

Based on patent status and recent regulatory filings, the competitive intensity for NDC 46122-0101 will fluctuate, dictating strategic pricing decisions.

3. Regulatory and Reimbursement Factors

Reimbursement policies, including Medicaid and Medicare formularies, influence drug accessibility and pricing. Payers increasingly favor cost-effective therapies, which may pressure the manufacturer to adjust prices downward or incentivize insurers to favor generics.

Recent policy shifts favoring biosimilars and generics, alongside price transparency initiatives, could further impact market dynamics.


Price Trends and Projections

Current Price Positioning

The current wholesale acquisition cost (WAC) for NDC 46122-0101 is roughly estimated to be in line with similar products in its class—ranging from $XXX to $XXX per unit or treatment course. Exact figures depend on dosage, form, and competitive positioning.

Note: Medical practitioners and pharmacy benefit managers often secure discounts and rebates, which significantly influence the net cost and real-world prices.

Historical Pricing Patterns

Over the past five years, similar drugs have experienced:

  • Stable or slight increases during patent exclusivity periods reflecting inflation and value addition.
  • Significant decreases following patent barriers expiring and generic entries, with average reductions of 30-70% within the first 2-3 years post-generic market entry.

Market Factors Influencing Future Prices

  • Patent Expiry and Exclusivity: If this drug's patent protection is nearing expiration, prices are forecasted to decline as generic competitors enter the market.
  • Innovations or Label Expansion: New indications, formulations, or delivery methods can sustain higher prices.
  • Manufacturing and Distribution Costs: Advances in manufacturing efficiency may enable pricing strategies that preserve margins despite competitive pressures.
  • Regulatory Changes: Price control legislation or importation policies may cap or reduce the drug’s price.

Price Projection Scenarios

Optimistic Scenario

  • Assumptions: Continued patent exclusivity, minimal generic competition, favorable reimbursement policies, and high demand.
  • Projection: Stabilization or slight increase in prices over the next 2-3 years, with potential growth of 2-5% annually, reaching approximately $XXX per unit.

Moderate Scenario

  • Assumptions: Entry of generics within 2 years, moderate payer pressure, implementation of value-based pricing.
  • Projection: A decline of 20-40% in prices over 3-4 years, with prices stabilizing at $XXX per unit.

Pessimistic Scenario

  • Assumptions: Rapid and aggressive generic entry, policy-driven price controls, and/or biosimilar competition.
  • Projection: Declines exceeding 50% over 2 years, potential introduction of biosimilar or alternative therapies driving prices below $XXX.

Strategic Insights

  • Patent Monitoring: Continuous surveillance of patent status and legal challenges can inform optimal timing for pricing strategies.
  • Market Differentiation: Innovations or expanded indications could sustain premium pricing and offset generic entry pressures.
  • Reimbursement Negotiations: Building strong relationships with payers and participating in risk-sharing arrangements can help maintain favorable pricing.
  • Cost Optimization: Investing in manufacturing efficiency can bolster margin resilience amid price declines.

Key Takeaways

  • The market for NDC 46122-0101 is subject to intense competition, especially from generic entrants, which will exert downward pressure on prices over the coming years.
  • Current price levels are influenced by patent protection, demand, and reimbursement landscape; these factors are critical for valuation.
  • Future price trajectories depend heavily on patent status, regulatory strategies, and market dynamics, with most scenarios indicating a potential decline in prices post-patent expiry.
  • Innovator companies should consider strategic investments in formulation, indications, and value-based pricing mechanisms to prolong product lifecycle and maximize revenue.
  • Stakeholders must closely monitor legislative, policy, and competitive developments to dynamically adjust pricing and market strategies.

FAQs

1. When is the patent for NDC 46122-0101 expected to expire?
Patent expiration timelines are specific to the manufacturer and patent filings. Typically, patents last 20 years from filing, with additional extensions possible. To obtain precise data, review the FDA’s Orange Book and the manufacturer’s patent filings.

2. How does generic entry influence the price of this drug?
Generic entry usually results in substantial price reductions—often between 30% to 70%. The extent depends on the number of competitors and payer formulary decisions.

3. Are biosimilars impacting the pricing of this drug?
If this drug is a biologic, biosimilar competitors could significantly reduce prices once approved and available, usually within 5-8 years of initial approval.

4. What role do payer negotiations play in setting the actual transaction price?
Rebates, discounts, and negotiations influence the net price paid by payers, which is often substantially lower than the WAC, impacting actual revenue for manufacturers.

5. What strategic steps should manufacturers take to maximize profits amid declining prices?
Investing in new indications, formulations, and value-based contracts, along with patent defense and market differentiation, can extend lifecycle and maintain profitability.


Sources

  1. FDA Orange Book (Drug Patent and Regulatory Data).
  2. IQVIA Institute for Human Data Science Reports.
  3. Centers for Medicare & Medicaid Services (CMS) Price and Reimbursement Data.
  4. Industry analyses on generic drug entry and pricing trends (Bloomberg, 2022).
  5. Patent timelines and legal case studies relevant to pharmaceutical industry.

Disclaimer: All projections are estimates based on current market conditions and available data. Actual market performance may differ due to unforeseen regulatory, competitive, or economic factors.

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