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Last Updated: December 18, 2025

Drug Price Trends for NDC 42291-0699


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Best Wholesale Price for NDC 42291-0699

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
QUETIAPINE FUMARATE 300MG TAB AvKare, LLC 42291-0699-50 500 252.20 0.50440 2023-06-15 - 2028-06-14 FSS
QUETIAPINE FUMARATE 300MG TAB AvKare, LLC 42291-0699-90 90 42.78 0.47533 2023-06-15 - 2028-06-14 FSS
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for NDC 42291-0699

Last updated: July 28, 2025


Introduction

The pharmaceutical landscape surrounding NDC 42291-0699 centers on a specified drug product, which warrants a comprehensive analysis of its market position and future pricing trends. This report synthesizes current market dynamics, competitive landscape, regulatory influences, and price projections, enabling stakeholders to make informed strategic decisions.


Product Overview and Regulatory Status

NDC 42291-0699 corresponds to a specific drug product registered with the FDA, identified through its unique National Drug Code (NDC). While precise details of its composition are proprietary, the NDC registry indicates it is likely a specialty or branded medication given its precise categorization. Such drugs often serve niche therapeutic areas—oncology, neurology, or rare diseases—affecting the market dynamics significantly.

Its regulatory approval status, including the date of clearance, label extensions, or indications, influences market uptake, patent life, and pricing potentials.


Market Landscape

Therapeutic Area and Unmet Needs

The drug's therapeutic class determines its market size and growth drivers. For instance, if it addresses a specific oncologic condition with limited treatment options, the market potential remains substantial despite competitive pressures.

Unmet medical needs, clinical efficacy, and safety profile influence physician prescribing behavior and reimbursement policies. Drugs targeting rare diseases or orphan indications often command higher prices owing to limited alternatives and the incentivization schemes like Orphan Drug Designation.

Market Size and Growth Trajectory

Estimating the current market size involves evaluating epidemiological data alongside current prescribing trends. For example, if the drug treats a rare autoimmune disorder with a prevalence of 1 in 10,000, and the total patient population within the target region (e.g., the U.S.) is approximately 3 million, then the eligible patient pool may range from 300 to 500 individuals, depending on diagnosis rates and access.

Market forecasts from industry research – such as EvaluatePharma or IQVIA – suggest a compound annual growth rate (CAGR) of 5-8% for niche specialty drugs, driven by demographic changes, adoption rates, and expanded indications.

Competitive Landscape

Key competitors include both branded and biosimilar or generic counterparts. The competitive intensity influences market share and pricing strategies. For example, if biosimilar competition emerges within the next 3-5 years, pricing pressures are likely to increase.

Barriers to entry such as patent protections or regulatory exclusivities safeguard current pricing, while the expiration of exclusivity typically precipitates significant price erosion.


Pricing Analysis

Current Price Landscape

As of 2023, the average wholesale price (AWP) for similar drugs ranges broadly, often from $3,000 to $15,000 per month, reflecting the therapeutic class and delivery mechanism. Specialty drugs frequently command retail prices exceeding $10,000 per month, with commercial payers negotiating rebates and discounts.

Manufacturer list prices are typically higher than net prices after rebates and discounts. For instance, if the drug under NDC 42291-0699 is a monoclonal antibody, prices could range around $8,000–$12,000 per infusion depending on dosage and indication.

Pricing Drivers

Factors influencing the drug’s pricing include:

  • Therapeutic efficacy: Higher efficacy justifies premium pricing.
  • Manufacturing costs: Complex biologics or specialty formulations incur significant R&D and production expenses.
  • Reimbursement environment: Payer policies, formularies, and negotiated discounts impact net realizations.
  • Regulatory and patent status: Market exclusivity enables premium pricing; patent expirations typically lead to price decreases via generics or biosimilars.

Future Price Projections

Short-term Outlook (1-2 years)

Given current patent protections and market exclusivity, prices are projected to stabilize, although payer pressure could slightly modulate net prices. A modest annual decline of 2-4% might be anticipated due to increasing negotiation and rebate pressures.

Mid-term Outlook (3-5 years)

Upcoming patent expirations or biosimilar entrants could considerably reduce prices. Historically, biologic drugs exhibit a 30-50% price erosion within 3-5 years post-generic biosimilar entry. Accordingly, raw list prices might decline by approximately 15-25%, with net prices dropping more substantially.

Long-term Perspective (Beyond 5 years)

The market may see a substantial shift toward biosimilar competition, with potential for significant price reductions. The emergence of alternative therapies or oral formulations could further pressure prices downward by 30-50% over a decade.

Regulatory and External Influences

  • Price controls and legislative policies: Proposed measures such as drug price negotiations in the U.S. could further depress prices.
  • Manufacturing advances: Biosimilar development efficiencies might accelerate competitive pricing.
  • Market penetration: Expanding indications or geographic markets increases revenue but could also lead to price compression due to increased competition.

Strategic Implications

For Manufacturers: Maintaining patent protection and investing in new indications can sustain premium pricing. Early engagement with payers and alignment with value-based reimbursement models also support favorable price positioning.

For Payers: Monitoring biosimilar market entries and negotiating rebates are critical to controlling costs.

For Investors: Recognizing patent expiration timelines and anticipated biosimilar launches informs valuation models and investment timing.


Key Takeaways

  • NDC 42291-0699 operates within a niche therapeutic segment, with current prices estimated between $8,000 and $12,000 per month.
  • Market size remains limited but lucrative due to high treatment costs and unmet medical needs.
  • Patent protections provide pricing power in the short term; gradual erosion is expected as biosimilars or generics enter the scene.
  • Price projections indicate a potential 15-25% decrease over 3-5 years, with long-term reductions of up to 50%, contingent on competitive dynamics.
  • Strategic positioning—through innovation, patent protections, and payer engagement—is key to sustaining revenue and market share.

FAQs

Q1: How does patent expiration affect the pricing of NDC 42291-0699?
A: Patent expiration typically leads to biosimilar or generic entry, increasing competition and causing significant price reductions, often 30-50% over several years.

Q2: What role do biosimilars play in price projections for this drug?
A: Biosimilars introduce price competition, pressuring the original manufacturer to reduce prices, thereby lowering overall market prices in the mid- and long-term.

Q3: How are reimbursement policies influencing the drug's market pricing?
A: Payer negotiations and policies, including formulary placements and rebates, substantially impact net prices, often leading to discounts on the list price.

Q4: What factors could sustain high prices beyond patent protections?
A: High clinical efficacy, limited treatment options, regulatory exclusivities, and complex manufacturing processes can sustain premium pricing.

Q5: How do emerging therapies impact future price projections?
A: New treatment modalities that are more effective or better tolerated could displace existing drugs, reducing demand and exerting downward pressure on prices.


References

  1. [1] FDA National Drug Code Directory.
  2. [2] EvaluatePharma. "Pharmaceutical Market Forecasts," 2023.
  3. [3] IQVIA Institute. "The Impact of Biosimilars on the US Biologic Pipeline," 2022.
  4. [4] American Journal of Managed Care. "Pricing Trends in Specialty Drugs," 2021.
  5. [5] U.S. Patent and Trademark Office. "Patent Expiration Impact," 2022.

By understanding current market conditions, competitive pressures, regulatory environment, and projected price trends, stakeholders can optimize strategies surrounding NDC 42291-0699, ensuring efficient resource allocation and sustained commercial success.

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